Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine series of compounds and analogues in Table 3B were synthesized and tested in 10-dose IC50 mode with 3 fold serial dilutions... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine series of compounds and analogues in Table 3B were synthesized and tested in 10-dose IC50 mode with 3 fold serial dilutions... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine series of compounds and analogues in Table 3B were synthesized and tested in 10-dose IC50 mode with 3 fold serial dilutions... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.01 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 4.02 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine series of compounds and analogues in Table 3B were synthesized and tested in 10-dose IC50 mode with 3 fold serial dilutions... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195768 (US9206188, 19 | US9834551, Example 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195780 (US9206188, 31 | US9834551, Example 31) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195782 (US9206188, 33 | US9834551, Example 33) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195797 (US9206188, 48 | US9834551, Example 48) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195799 (US9206188, 50 | US9834551, Example 50) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195828 (US9206188, 79 | US9834551, Example 79) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195831 (US9206188, 82 | US9834551, Example 82) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195904 (US9206188, 145 | US9834551, Example 145) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195907 (US9206188, 152 | US9834551, Example 152) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195754 (US9206188, 5 | US9834551, Example 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195756 (US9206188, 7 | US9834551, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195769 (US9206188, 20 | US9834551, Example 20) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195778 (US9206188, 29 | US9834551, Example 29) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195827 (US9206188, 78 | US9834551, Example 78) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195829 (US9206188, 80 | US9834551, Example 80) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195834 (US9206188, 85 | US9834551, Example 85) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195906 (US9206188, 150 | US9834551, Example 150) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195771 (US9206188, 22 | US9834551, Example 22) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195830 (US9206188, 81 | US9834551, Example 81) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195833 (US9206188, 84 | US9834551, Example 84) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195838 (US9206188, 89 | US9834551, Example 89) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195902 (US9206188, 138 | US9834551, Example 138) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195908 (US9206188, 153 | US9834551, Example 153) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195840 (US9206188, 91 | US9834551, Example 91) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195772 (US9206188, 23 | US9834551, Example 23) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195798 (US9206188, 49 | US9834551, Example 49) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195808 (US9206188, 59 | US9834551, Example 59) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195835 (US9206188, 86 | US9834551, Example 86) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195836 (US9206188, 87 | US9834551, Example 87) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195837 (US9206188, 88 | US9834551, Example 88) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195774 (US9206188, 25 | US9834551, Example 25) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195800 (US9206188, 51 | US9834551, Example 51) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195832 (US9206188, 83 | US9834551, Example 83) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195841 (US9206188, 92 | US9834551, Example 92) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195901 (US9206188, 133 | US9834551, Example 133) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195757 (US9206188, 8 | US9834551, Example 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195775 (US9206188, 26 | US9834551, Example 26) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195779 (US9206188, 30 | US9834551, Example 30) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195826 (US9206188, 77 | US9834551, Example 77) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195905 (US9206188, 148 | US9834551, Example 148) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195903 (US9206188, 140 | US9834551, Example 140) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195777 (US9206188, 28 | US9834551, Example 28) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195781 (US9206188, 32 | US9834551, Example 32) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195806 (US9206188, 57 | US9834551, Example 57) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM195807 (US9206188, 58 | US9834551, Example 58) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ARRIEN PHARMACEUTICALS LLC US Patent | Assay Description 1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja... | US Patent US9206188 (2015) BindingDB Entry DOI: 10.7270/Q2057DRT | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 228 total ) | Next | Last >> |