Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205241 (US9249123, 102) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205242 (BDBM205248 | US9249123, 104) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 24.7 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205243 (US9249123, 127) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 29.4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205246 (US9249123, 130) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 33.7 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205240 (US9249123, 101) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 36.4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205247 (US9249123, 131) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 47.4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205242 (BDBM205248 | US9249123, 104) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 95 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM205249 (US9249123, 161) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 245 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Genentech, Inc.; Gilead Connecticut, Inc. US Patent | Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt... | US Patent US9249123 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TG8 | |||||||||||
More data for this Ligand-Target Pair |