Affinity Data by Patent

Patent code US9249139

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205353 (US9249139, 1j) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205346 (US9249139, 1c) Show SMILES CCOC(=O)c1cc(Cc2cccc(F)c2)c(=O)n2CCCc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.5	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205354 (US9249139, 1k) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67.3	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205350 (US9249139, 1g) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205348 (US9249139, 1e) Show SMILES CCOC(=O)c1cc(Cc2ccccc2Cl)c(=O)n2CCCc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205344 (US9249139, 1a) Show SMILES CCOC(=O)c1cc(Cc2ccccc2)c(=O)n2CCCc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	435	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205351 (US9249139, 1h) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	577	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM205347 (US9249139, 1d) Show SMILES CCOC(=O)c1cc(Cc2ccc(F)cc2)c(=O)n2CCCc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM15296 (6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...) Show SMILES Cc1[nH]c(=O)c(cc1-c1ccncc1)C#N Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	22
Council of Scientific & Industrial Research US Patent					Assay Description PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay System (catalogue No. BML-AK800-0001). The Platelets isolated from human blood ...				US Patent US9249139 (2016) BindingDB Entry DOI: 10.7270/Q27W6B1M
Council of Scientific & Industrial Research US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%