Affinity Data by Patent

Patent code US9273052

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM209856 (US9273052, 15 \| US9566277, 15) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	25
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...				US Patent US9273052 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MWG
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM209854 (US9273052, 2 \| US9566277, 2) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	25
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...				US Patent US9273052 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MWG
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM209857 (US9273052, 19 \| US9566277, 19) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	25
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...				US Patent US9273052 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MWG
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM209853 (US9273052, 1 \| US9566277, 1) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	25
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...				US Patent US9273052 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MWG
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM209855 (US9273052, 3 \| US9566277, 3) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	25
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...				US Patent US9273052 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MWG
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					More data for this Ligand-Target Pair

Reorder this table by EC50
Reorder this table by IC50
Reorder this table by Kd
Reorder this table by KON
Reorder this table by KOFF
Reorder this table by pH
Reorder this table by T
Reorder this table by ΔH°
Reorder this table by -TΔS°
Change energy units to:kcal/mole

* indicates data uncertainty>20%