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Patent code US9283225

Compile Data Set for Download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage-stimulating protein receptor [983-1400,G1195S]


(Homo sapiens (Human))		BDBM213708
PNG
(US9283225, A1)
Show SMILES Fc1cc(NC(=O)c2cnn(c2C(F)(F)F)-c2ccccc2)ccc1Oc1ccnc2NC(=O)NCc12
Show InChI InChI=1S/C24H16F4N6O3/c25-17-10-13(6-7-19(17)37-18-8-9-29-21-15(18)11-30-23(36)33-21)32-22(35)16-12-31-34(20(16)24(26,27)28)14-4-2-1-3-5-14/h1-10,12H,11H2,(H,32,35)(H2,29,30,33,36)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.30n/an/an/an/a7.525



Merck Patent GmbH

US Patent


Assay Description
The kinase assay was carried out as 384-well FlashPlate assay. As test plates 384-well streptavidine coated FlashPlate microtitre plates from Perkin ...

US Patent US9283225 (2016)


BindingDB Entry DOI: 10.7270/Q2959GC8
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor [983-1400,G1195S]


(Homo sapiens (Human))		BDBM213709
PNG
(US9283225, A3)
Show SMILES Cc1c(cnn1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3NC(=O)NCc23)c(F)c1
Show InChI InChI=1S/C24H19FN6O3/c1-14-17(13-28-31(14)16-5-3-2-4-6-16)23(32)29-15-7-8-21(19(25)11-15)34-20-9-10-26-22-18(20)12-27-24(33)30-22/h2-11,13H,12H2,1H3,(H,29,32)(H2,26,27,30,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/a7.525



Merck Patent GmbH

US Patent


Assay Description
The kinase assay was carried out as 384-well FlashPlate assay. As test plates 384-well streptavidine coated FlashPlate microtitre plates from Perkin ...

US Patent US9283225 (2016)


BindingDB Entry DOI: 10.7270/Q2959GC8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%