Affinity Data by Patent

Patent code US9290463

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A/2C (Homo sapiens (Human))	BDBM50024605 (CHEMBL3330603 \| US9290463, E) Show SMILES Cn1c(=O)cnn(CCCCN2CCN(CC2)c2ccccc2)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.150	-52.1	n/a	n/a	n/a	n/a	n/a	7.4	4
The Trustees of Columbia University in the City of New York US Patent					Assay Description Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...				US Patent US9290463 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RK0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/2C (Homo sapiens (Human))	BDBM50024573 (CHEMBL3330617 \| US9290463, A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	4	-44.6	n/a	n/a	n/a	n/a	n/a	7.4	4
The Trustees of Columbia University in the City of New York US Patent					Assay Description Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...				US Patent US9290463 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RK0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/2C (Homo sapiens (Human))	BDBM210829 (US9290463, B) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.5	-43.8	n/a	n/a	n/a	n/a	n/a	7.4	4
The Trustees of Columbia University in the City of New York US Patent					Assay Description Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...				US Patent US9290463 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RK0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/2C (Homo sapiens (Human))	BDBM210830 (US9290463, D) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	-43.6	n/a	n/a	n/a	n/a	n/a	7.4	4
The Trustees of Columbia University in the City of New York US Patent					Assay Description Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...				US Patent US9290463 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RK0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/2C (Homo sapiens (Human))	BDBM50024603 (CHEMBL3330604 \| US9290463, C) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	58.3	-38.4	n/a	n/a	n/a	n/a	n/a	7.4	4
The Trustees of Columbia University in the City of New York US Patent					Assay Description Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...				US Patent US9290463 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RK0
					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%