Affinity Data by Patent

Patent code US9290481

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211959 (US9290481, 3.1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211951 (US9290481, 1.2) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM50076187 (CHEMBL3416027 \| US9290481, 1.4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211960 (US9290481, 4.2) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM50076189 (CHEMBL3416024 \| US9290481, 4.1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211952 (US9290481, 1.3) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211958 (US9290481, 2.6) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211954 (US9290481, 2.2) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211955 (US9290481, 2.3) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211953 (US9290481, 2.1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM50076185 (CHEMBL3416026 \| US9290481, 1.1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211957 (US9290481, 2.5) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [2-635] (Homo sapiens (Human))	BDBM211956 (US9290481, 2.4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...				US Patent US9290481 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZPR
NOVARTIS AG US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%