Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM221893 (US9315438, Compound represented by formula (II)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM221897 (US9315438, Reference compound 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.63 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM221894 (US9315438, Compound represented by formula (III)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.83 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM221896 (US9315438, Compound represented by formula (V)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 282 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM221895 (US9315438, Compound represented by formula (IV)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM221897 (US9315438, Reference compound 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM221894 (US9315438, Compound represented by formula (III)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.08E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM221893 (US9315438, Compound represented by formula (II)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.72E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM221896 (US9315438, Compound represented by formula (V)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.55E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM221895 (US9315438, Compound represented by formula (IV)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.11E+5 | n/a | n/a | n/a | n/a | n/a | 37 |
XUANZHU PHARMA CO., LTD US Patent | Assay Description Human SGLT-2 and SGLT-1 sequences were stably expressed in the CHO cells. The cell culture was conducted in a 96-well plate for 12 hr. The plate was ... | US Patent US9315438 (2016) BindingDB Entry DOI: 10.7270/Q28P5ZBZ | |||||||||||
More data for this Ligand-Target Pair |