Found 33 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223499
(US9321728, 11)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.51,2.41,;-5.26,3.32,;-4.02,4.22,;-6.17,4.56,;-4.36,2.07,;-10.42,1.64,;-11.19,2.98,;-12.73,2.98,;-13.5,1.64,;-12.73,.31,;-11.19,.31,;-10.42,-1.02,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H27ClF3N3O5/c29-21-4-2-1-3-20(21)27-35-24(25(40-27)28(30,31)32)26(39)33-14-13-22(36)34-19-11-9-18(10-12-19)17-7-5-16(6-8-17)15-23(37)38/h1-4,9-12,16-17H,5-8,13-15H2,(H,33,39)(H,34,36)(H,37,38)/t16-,17? | PDB
UniProtKB/SwissProt
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| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223519
(US9321728, 69)Show SMILES [O-]C(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2c(Cl)cccc2Cl)cc1 |r,wU:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;$,(8.39,-.06,;8.39,1.48,;9.72,2.25,;7.06,2.25,;5.72,1.48,;5.72,-.06,;4.39,-.83,;3.06,-.06,;3.06,1.48,;4.39,2.25,;1.72,-.83,;.39,-.06,;-.95,-.83,;-.95,-2.37,;-2.28,-3.14,;-2.28,-4.68,;-.95,-5.45,;-3.61,-5.45,;-4.95,-4.68,;-4.95,-3.14,;-6.28,-2.37,;-7.61,-3.14,;-6.28,-.83,;-5.03,.07,;-5.51,1.54,;-7.05,1.54,;-7.53,.07,;-8.99,-.4,;-10.46,-.88,;-9.47,1.06,;-8.51,-1.87,;-4.6,2.78,;-5.23,4.19,;-6.76,4.35,;-4.33,5.44,;-2.79,5.27,;-2.17,3.87,;-3.07,2.62,;-2.45,1.21,;.39,-3.14,;1.72,-2.37,)| Show InChI InChI=1S/C28H26Cl2F3N3O5/c29-19-2-1-3-20(30)23(19)27-36-24(25(41-27)28(31,32)33)26(40)34-13-12-21(37)35-18-10-8-17(9-11-18)16-6-4-15(5-7-16)14-22(38)39/h1-3,8-11,15-16H,4-7,12-14H2,(H,34,40)(H,35,37)(H,38,39)/p-1/t15-,16? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223522
(US9321728, 79)Show SMILES [O-]C(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2Cl)cc1 |r,wU:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;$,(9.01,-6.37,;10.34,-5.6,;11.67,-6.37,;10.34,-4.06,;9.01,-3.29,;7.67,-4.06,;6.34,-3.29,;6.34,-1.75,;7.67,-.98,;9.01,-1.75,;5,-.98,;5,.56,;3.67,1.33,;2.34,.56,;1,1.33,;-.33,.56,;-.33,-.98,;-1.66,1.33,;-3,.56,;-4.33,1.33,;-5.66,.56,;-5.66,-.98,;-7,1.33,;-8.41,.7,;-9.44,1.84,;-8.67,3.18,;-7.16,2.86,;-6.02,3.89,;-4.87,4.92,;-7.05,5.03,;-4.98,2.74,;-10.97,1.68,;-11.87,2.93,;-13.4,2.77,;-14.03,1.36,;-13.13,.12,;-11.59,.28,;-10.69,-.97,;2.34,-.98,;3.67,-1.75,)| Show InChI InChI=1S/C28H27ClF3N3O5/c29-21-4-2-1-3-20(21)27-35-24(25(40-27)28(30,31)32)26(39)33-14-13-22(36)34-19-11-9-18(10-12-19)17-7-5-16(6-8-17)15-23(37)38/h1-4,9-12,16-17H,5-8,13-15H2,(H,33,39)(H,34,36)(H,37,38)/p-1/t16-,17? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223508
(US9321728, 41)Show SMILES NC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cc1 |r,wD:4.3,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.47,2.44,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,;-10.42,1.64,;-11.19,.31,;-12.73,.31,;-13.5,1.64,;-12.73,2.98,;-11.19,2.98,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H29F3N4O4/c29-28(30,31)25-24(35-27(39-25)20-4-2-1-3-5-20)26(38)33-15-14-23(37)34-21-12-10-19(11-13-21)18-8-6-17(7-9-18)16-22(32)36/h1-5,10-13,17-18H,6-9,14-16H2,(H2,32,36)(H,33,38)(H,34,37)/t17-,18? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223527
(US9321728, 95)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2Cl)-c2ccccc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;$,(13.5,-4.41,;12.16,-3.64,;12.16,-2.1,;10.83,-4.41,;9.5,-3.64,;9.5,-2.1,;8.16,-1.33,;6.83,-2.1,;6.83,-3.64,;8.16,-4.41,;5.5,-1.33,;4.16,-2.1,;2.83,-1.33,;2.83,.21,;1.49,.98,;.16,.21,;.16,-1.33,;-1.17,.98,;-2.51,.21,;-3.84,.98,;-5.17,.21,;-5.17,-1.33,;-6.51,.98,;-7.97,.5,;-8.88,1.75,;-7.97,2.99,;-6.51,2.52,;-5.17,3.29,;-10.42,1.75,;-11.19,.41,;-12.73,.41,;-13.5,1.75,;-12.73,3.08,;-11.19,3.08,;-10.42,4.41,;4.16,.98,;5.5,.21,)| Show InChI InChI=1S/C27H27Cl2N3O5/c28-21-4-2-1-3-20(21)27-32-24(25(29)37-27)26(36)30-14-13-22(33)31-19-11-9-18(10-12-19)17-7-5-16(6-8-17)15-23(34)35/h1-4,9-12,16-17H,5-8,13-15H2,(H,30,36)(H,31,33)(H,34,35)/t16-,17? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223497
(US9321728, 6)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.51,2.41,;-5.26,3.32,;-4.02,4.22,;-6.17,4.56,;-4.36,2.07,;-10.42,1.64,;-11.19,2.98,;-12.73,2.98,;-13.5,1.64,;-12.73,.31,;-11.19,.31,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H28F3N3O5/c29-28(30,31)25-24(34-27(39-25)20-4-2-1-3-5-20)26(38)32-15-14-22(35)33-21-12-10-19(11-13-21)18-8-6-17(7-9-18)16-23(36)37/h1-5,10-13,17-18H,6-9,14-16H2,(H,32,38)(H,33,35)(H,36,37)/t17-,18? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223496
(US9321728, 4)Show SMILES CCOc1ccc(cc1)C(=O)NCCC(=O)Nc1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:26.28,(-13.34,-3.85,;-12,-3.08,;-10.67,-3.85,;-9.34,-3.08,;-9.34,-1.54,;-8,-.77,;-6.67,-1.54,;-6.67,-3.08,;-8,-3.85,;-5.33,-.77,;-5.33,.77,;-4,-1.54,;-2.67,-.77,;-1.33,-1.54,;,-.77,;,.77,;1.33,-1.54,;2.67,-.77,;4,-1.54,;5.33,-.77,;5.33,.77,;4,1.54,;2.67,.77,;6.67,1.54,;6.67,3.08,;8,3.85,;9.34,3.08,;10.67,3.85,;12,3.08,;13.34,3.85,;12,1.54,;9.34,1.54,;8,.77,)| Show InChI InChI=1S/C26H32N2O5/c1-2-33-23-13-9-21(10-14-23)26(32)27-16-15-24(29)28-22-11-7-20(8-12-22)19-5-3-18(4-6-19)17-25(30)31/h7-14,18-19H,2-6,15-17H2,1H3,(H,27,32)(H,28,29)(H,30,31)/t18-,19? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223525
(US9321728, 93)Show SMILES CCc1ccc(cc1)-c1ccc(cc1)C(=O)NCCC(=O)Nc1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:31.34,$;;;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;$,(-13.75,6.57,;-13.75,5.03,;-12.41,4.26,;-11.03,5,;-9.7,4.23,;-9.7,2.69,;-11.03,1.92,;-12.36,2.69,;-8.18,1.92,;-6.85,2.69,;-5.52,1.92,;-5.52,.38,;-6.85,-.38,;-8.18,.38,;-4.18,-.38,;-4.18,-1.93,;-2.85,.38,;-1.51,-.38,;-.18,.38,;1.15,-.38,;1.15,-1.93,;2.49,.38,;3.82,-.38,;3.82,-1.93,;5.15,-2.69,;6.49,-1.93,;6.49,-.38,;5.15,.38,;7.82,-2.69,;9.16,-1.93,;10.49,-2.69,;10.49,-4.23,;12,-5,;13.52,-4.23,;15.03,-5,;13.52,-2.69,;9.16,-5,;7.82,-4.23,)| Show InChI InChI=1S/C32H36N2O4/c1-2-22-3-7-24(8-4-22)26-11-13-28(14-12-26)32(38)33-20-19-30(35)34-29-17-15-27(16-18-29)25-9-5-23(6-10-25)21-31(36)37/h3-4,7-8,11-18,23,25H,2,5-6,9-10,19-21H2,1H3,(H,33,38)(H,34,35)(H,36,37)/t23-,25? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223526
(US9321728, 94)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2ccc(c(Cl)c2)-c2ccccc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;$,(13.34,-5,;12,-4.23,;12,-2.69,;10.67,-5,;9.34,-4.23,;9.34,-2.69,;8,-1.93,;6.67,-2.69,;6.67,-4.23,;8,-5,;5.33,-1.93,;4,-2.69,;2.67,-1.93,;2.67,-.38,;1.33,.38,;,-.38,;,-1.93,;-1.33,.38,;-2.67,-.38,;-4,.38,;-5.33,-.38,;-5.33,-1.93,;-6.67,.38,;-6.67,1.93,;-8,2.69,;-9.34,1.93,;-9.34,.38,;-10.67,-.38,;-8,-.38,;-10.67,2.69,;-10.67,4.23,;-12,5,;-13.34,4.23,;-13.34,2.69,;-12,1.93,;4,.38,;5.33,-.38,)| Show InChI InChI=1S/C30H31ClN2O4/c31-27-19-24(12-15-26(27)23-4-2-1-3-5-23)30(37)32-17-16-28(34)33-25-13-10-22(11-14-25)21-8-6-20(7-9-21)18-29(35)36/h1-5,10-15,19-21H,6-9,16-18H2,(H,32,37)(H,33,34)(H,35,36)/t20-,21? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223518
(US9321728, 68)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2c(Cl)cccc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.47,2.44,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,;-10.42,1.64,;-11.19,2.98,;-10.42,4.31,;-12.73,2.98,;-13.5,1.64,;-12.73,.31,;-11.19,.31,;-10.42,-1.02,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H26Cl2F3N3O5/c29-19-2-1-3-20(30)23(19)27-36-24(25(41-27)28(31,32)33)26(40)34-13-12-21(37)35-18-10-8-17(9-11-18)16-6-4-15(5-7-16)14-22(38)39/h1-3,8-11,15-16H,4-7,12-14H2,(H,34,40)(H,35,37)(H,38,39)/t15-,16? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223514
(US9321728, 60)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2F)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.47,2.44,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,;-10.42,1.64,;-11.19,.31,;-12.73,.31,;-13.5,1.64,;-12.73,2.98,;-11.19,2.98,;-10.42,4.31,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H27F4N3O5/c29-21-4-2-1-3-20(21)27-35-24(25(40-27)28(30,31)32)26(39)33-14-13-22(36)34-19-11-9-18(10-12-19)17-7-5-16(6-8-17)15-23(37)38/h1-4,9-12,16-17H,5-8,13-15H2,(H,33,39)(H,34,36)(H,37,38)/t16-,17? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223517
(US9321728, 66)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2C(F)(F)F)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;$,(13.5,-5.08,;12.16,-4.31,;12.16,-2.77,;10.83,-5.08,;9.5,-4.31,;9.5,-2.77,;8.16,-2,;6.83,-2.77,;6.83,-4.31,;8.16,-5.08,;5.5,-2,;4.16,-2.77,;2.83,-2,;2.83,-.46,;1.49,.31,;.16,-.46,;.16,-2,;-1.17,.31,;-2.51,-.46,;-3.84,.31,;-5.17,-.46,;-5.17,-2,;-6.51,.31,;-7.97,-.17,;-8.88,1.08,;-7.97,2.33,;-6.47,1.87,;-5.23,2.78,;-3.98,3.68,;-6.13,4.02,;-4.32,1.53,;-10.42,1.08,;-11.19,-.25,;-12.73,-.25,;-13.5,1.08,;-12.73,2.41,;-11.16,2.46,;-10.39,3.79,;-9.62,5.13,;-11.72,4.56,;-9.06,3.02,;4.16,.31,;5.5,-.46,)| Show InChI InChI=1S/C29H27F6N3O5/c30-28(31,32)21-4-2-1-3-20(21)27-38-24(25(43-27)29(33,34)35)26(42)36-14-13-22(39)37-19-11-9-18(10-12-19)17-7-5-16(6-8-17)15-23(40)41/h1-4,9-12,16-17H,5-8,13-15H2,(H,36,42)(H,37,39)(H,40,41)/t16-,17? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223516
(US9321728, 65)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2Br)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.47,2.44,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,;-10.42,1.64,;-11.19,2.98,;-12.73,2.98,;-13.5,1.64,;-12.73,.31,;-11.19,.31,;-10.42,-1.02,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H27BrF3N3O5/c29-21-4-2-1-3-20(21)27-35-24(25(40-27)28(30,31)32)26(39)33-14-13-22(36)34-19-11-9-18(10-12-19)17-7-5-16(6-8-17)15-23(37)38/h1-4,9-12,16-17H,5-8,13-15H2,(H,33,39)(H,34,36)(H,37,38)/t16-,17? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223515
(US9321728, 64)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccc(Cl)cc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;$,(14.27,-4.52,;12.93,-3.75,;12.93,-2.21,;11.6,-4.52,;10.27,-3.75,;10.27,-2.21,;8.93,-1.44,;7.6,-2.21,;7.6,-3.75,;8.93,-4.52,;6.27,-1.44,;4.93,-2.21,;3.6,-1.44,;3.6,.1,;2.26,.87,;.93,.1,;.93,-1.44,;-.4,.87,;-1.74,.1,;-3.07,.87,;-4.4,.1,;-4.4,-1.44,;-5.74,.87,;-7.2,.4,;-8.11,1.64,;-7.2,2.89,;-5.7,2.44,;-4.46,3.34,;-3.21,4.25,;-5.36,4.59,;-3.55,2.1,;-9.65,1.64,;-10.42,2.98,;-11.96,2.98,;-12.73,1.64,;-14.27,1.64,;-11.96,.31,;-10.42,.31,;-9.65,-1.02,;4.93,.87,;6.27,.1,)| Show InChI InChI=1S/C28H26Cl2F3N3O5/c29-18-7-10-20(21(30)14-18)27-36-24(25(41-27)28(31,32)33)26(40)34-12-11-22(37)35-19-8-5-17(6-9-19)16-3-1-15(2-4-16)13-23(38)39/h5-10,14-16H,1-4,11-13H2,(H,34,40)(H,35,37)(H,38,39)/t15-,16? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223528
(US9321728, 105)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2c(Cl)cc(F)cc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;$,(14.27,-4.52,;12.93,-3.75,;12.93,-2.21,;11.6,-4.52,;10.27,-3.75,;10.27,-2.21,;8.93,-1.44,;7.6,-2.21,;7.6,-3.75,;8.93,-4.52,;6.27,-1.44,;4.93,-2.21,;3.6,-1.44,;3.6,.1,;2.26,.87,;.93,.1,;.93,-1.44,;-.4,.87,;-1.74,.1,;-3.07,.87,;-4.4,.1,;-4.4,-1.44,;-5.74,.87,;-7.2,.4,;-8.11,1.64,;-7.2,2.89,;-5.65,2.43,;-4.39,3.32,;-3.13,4.21,;-5.27,4.58,;-3.5,2.06,;-9.65,1.64,;-10.42,2.98,;-9.65,4.31,;-11.96,2.98,;-12.73,1.64,;-14.27,1.64,;-11.96,.31,;-10.42,.31,;-9.65,-1.02,;4.93,.87,;6.27,.1,)| Show InChI InChI=1S/C28H25Cl2F4N3O5/c29-19-12-17(31)13-20(30)23(19)27-37-24(25(42-27)28(32,33)34)26(41)35-10-9-21(38)36-18-7-5-16(6-8-18)15-3-1-14(2-4-15)11-22(39)40/h5-8,12-15H,1-4,9-11H2,(H,35,41)(H,36,38)(H,39,40)/t14-,15? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223502
(US9321728, 21)Show SMILES Cc1ccccc1-c1nc(C(=O)NCCC(=O)Nc2ccc(cc2)C2CC[C@H](CC(O)=O)CC2)c(o1)C(F)(F)F |r,wD:27.29,$;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;$,(-10.42,4.31,;-11.19,2.98,;-12.73,2.98,;-13.5,1.64,;-12.73,.31,;-11.19,.31,;-10.42,1.64,;-8.88,1.64,;-7.97,.4,;-6.51,.87,;-5.17,.1,;-5.17,-1.44,;-3.84,.87,;-2.51,.1,;-1.17,.87,;.16,.1,;.16,-1.44,;1.49,.87,;2.83,.1,;2.83,-1.44,;4.16,-2.21,;5.5,-1.44,;5.5,.1,;4.16,.87,;6.83,-2.21,;8.16,-1.44,;9.5,-2.21,;9.5,-3.75,;10.83,-4.52,;12.16,-3.75,;13.5,-4.52,;12.16,-2.21,;8.16,-4.52,;6.83,-3.75,;-6.47,2.44,;-7.97,2.89,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,)| Show InChI InChI=1S/C29H30F3N3O5/c1-17-4-2-3-5-22(17)28-35-25(26(40-28)29(30,31)32)27(39)33-15-14-23(36)34-21-12-10-20(11-13-21)19-8-6-18(7-9-19)16-24(37)38/h2-5,10-13,18-19H,6-9,14-16H2,1H3,(H,33,39)(H,34,36)(H,37,38)/t18-,19? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223523
(US9321728, 86)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2ccc(cc2)-c2ccccc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;$,(13.7,-5,;12.18,-4.23,;12.18,-2.69,;10.67,-5,;9.16,-4.23,;9.16,-2.69,;7.82,-1.92,;6.49,-2.69,;6.49,-4.23,;7.82,-5,;5.15,-1.92,;3.82,-2.69,;2.49,-1.92,;2.49,-.38,;1.15,.39,;-.18,-.38,;-.18,-1.92,;-1.51,.39,;-2.85,-.38,;-4.18,.39,;-5.52,-.38,;-5.52,-1.92,;-6.85,.39,;-6.85,1.92,;-8.18,2.69,;-9.52,1.92,;-9.52,.39,;-8.18,-.38,;-11.03,2.69,;-12.36,1.92,;-13.7,2.69,;-13.7,4.23,;-12.36,5,;-11.03,4.23,;-9.7,5,;3.82,.39,;5.15,-.38,)| Show InChI InChI=1S/C30H31ClN2O4/c31-27-4-2-1-3-26(27)23-9-11-24(12-10-23)30(37)32-18-17-28(34)33-25-15-13-22(14-16-25)21-7-5-20(6-8-21)19-29(35)36/h1-4,9-16,20-21H,5-8,17-19H2,(H,32,37)(H,33,34)(H,35,36)/t20-,21? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223509
(US9321728, 47)Show SMILES Cc1ccc(cc1)-n1cc(C(=O)NCCC(=O)Nc2ccc(cc2)C2CC[C@H](CC(O)=O)CC2)c(n1)C(F)(F)F |r,wD:27.29,$;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;$,(-14.27,1.64,;-12.73,1.64,;-11.96,.31,;-10.42,.31,;-9.65,1.64,;-10.42,2.98,;-11.96,2.98,;-8.11,1.64,;-7.2,.4,;-5.74,.87,;-4.4,.1,;-4.4,-1.44,;-3.07,.87,;-1.74,.1,;-.4,.87,;.93,.1,;.93,-1.44,;2.26,.87,;3.6,.1,;3.6,-1.44,;4.93,-2.21,;6.27,-1.44,;6.27,.1,;4.93,.87,;7.6,-2.21,;8.93,-1.44,;10.27,-2.21,;10.27,-3.75,;11.6,-4.52,;12.93,-3.75,;14.27,-4.52,;12.93,-2.21,;8.93,-4.52,;7.6,-3.75,;-5.7,2.44,;-7.2,2.89,;-4.46,3.34,;-3.21,4.25,;-5.36,4.59,;-3.55,2.1,)| Show InChI InChI=1S/C29H31F3N4O4/c1-18-2-12-23(13-3-18)36-17-24(27(35-36)29(30,31)32)28(40)33-15-14-25(37)34-22-10-8-21(9-11-22)20-6-4-19(5-7-20)16-26(38)39/h2-3,8-13,17,19-20H,4-7,14-16H2,1H3,(H,33,40)(H,34,37)(H,38,39)/t19-,20? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223520
(US9321728, 73)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2c(F)cccc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.47,2.44,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,;-10.42,1.64,;-11.19,.31,;-10.42,-1.02,;-12.73,.31,;-13.5,1.64,;-12.73,2.98,;-11.19,2.98,;-10.42,4.31,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H26ClF4N3O5/c29-19-2-1-3-20(30)23(19)27-36-24(25(41-27)28(31,32)33)26(40)34-13-12-21(37)35-18-10-8-17(9-11-18)16-6-4-15(5-7-16)14-22(38)39/h1-3,8-11,15-16H,4-7,12-14H2,(H,34,40)(H,35,37)(H,38,39)/t15-,16? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223498
(US9321728, 7)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2cn(nc2C(F)(F)F)-c2ccccc2)cc1 |r,wD:4.3,(12.3,5.78,;10.97,5.01,;10.97,3.47,;9.64,5.78,;8.3,5.01,;6.97,5.78,;5.64,5.01,;5.64,3.47,;6.97,2.7,;8.3,3.47,;4.3,2.7,;4.3,1.16,;2.97,.39,;1.64,1.16,;.3,.39,;-1.03,1.16,;-1.03,2.7,;-2.37,.39,;-3.7,1.16,;-5.03,.39,;-6.37,1.16,;-6.37,2.7,;-7.7,.39,;-7.7,-1.15,;-9.17,-1.63,;-10.07,-.38,;-9.17,.87,;-9.94,2.2,;-10.71,3.53,;-11.27,1.43,;-8.6,2.97,;-9.98,-3.11,;-11.52,-3.1,;-12.3,-4.42,;-11.55,-5.76,;-10.01,-5.78,;-9.22,-4.46,;1.64,2.7,;2.97,3.47,)| Show InChI InChI=1S/C28H29F3N4O4/c29-28(30,31)26-23(17-35(34-26)22-4-2-1-3-5-22)27(39)32-15-14-24(36)33-21-12-10-20(11-13-21)19-8-6-18(7-9-19)16-25(37)38/h1-5,10-13,17-19H,6-9,14-16H2,(H,32,39)(H,33,36)(H,37,38)/t18-,19? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223507
(US9321728, 37)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2sc(nc2C(F)(F)F)-c2ccccc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.47,2.44,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,;-10.42,1.64,;-11.19,.31,;-12.73,.31,;-13.5,1.64,;-12.73,2.98,;-11.19,2.98,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H28F3N3O4S/c29-28(30,31)25-24(39-27(34-25)20-4-2-1-3-5-20)26(38)32-15-14-22(35)33-21-12-10-19(11-13-21)18-8-6-17(7-9-18)16-23(36)37/h1-5,10-13,17-18H,6-9,14-16H2,(H,32,38)(H,33,35)(H,36,37)/t17-,18? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223524
(US9321728, 87)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2Cl)-c2ccccc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;$,(10.16,-5.01,;11.5,-4.24,;12.83,-5.01,;11.5,-2.69,;10.16,-1.93,;10.16,-.38,;8.83,.38,;7.5,-.38,;7.5,-1.93,;8.83,-2.69,;6.16,.38,;4.83,-.38,;3.49,.38,;3.49,1.93,;2.16,2.69,;.83,1.93,;.83,.38,;-.51,2.69,;-1.84,1.93,;-3.17,2.69,;-4.51,1.93,;-4.51,.38,;-5.84,2.69,;-7.31,2.22,;-8.21,3.47,;-7.31,4.71,;-5.84,4.24,;-4.51,5.01,;-9.75,3.47,;-10.52,2.13,;-12.06,2.13,;-12.83,3.47,;-12.06,4.8,;-10.52,4.8,;4.83,2.69,;6.16,1.93,)| Show InChI InChI=1S/C27H28ClN3O5/c28-25-24(31-27(36-25)20-4-2-1-3-5-20)26(35)29-15-14-22(32)30-21-12-10-19(11-13-21)18-8-6-17(7-9-18)16-23(33)34/h1-5,10-13,17-18H,6-9,14-16H2,(H,29,35)(H,30,32)(H,33,34)/t17-,18? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223500
(US9321728, 15)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2oc(nc2C(F)(F)F)-c2ccccc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.51,2.41,;-5.26,3.32,;-4.02,4.22,;-6.17,4.56,;-4.36,2.07,;-10.42,1.64,;-11.19,2.98,;-12.73,2.98,;-13.5,1.64,;-12.73,.31,;-11.19,.31,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H28F3N3O5/c29-28(30,31)25-24(39-27(34-25)20-4-2-1-3-5-20)26(38)32-15-14-22(35)33-21-12-10-19(11-13-21)18-8-6-17(7-9-18)16-23(36)37/h1-5,10-13,17-18H,6-9,14-16H2,(H,32,38)(H,33,35)(H,36,37)/t17-,18? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223510
(US9321728, 49)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2cn(nc2C(F)(F)F)-c2ccc(Cl)cc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;$,(14.27,-4.52,;12.93,-3.75,;12.93,-2.21,;11.6,-4.52,;10.27,-3.75,;10.27,-2.21,;8.93,-1.44,;7.6,-2.21,;7.6,-3.75,;8.93,-4.52,;6.27,-1.44,;4.93,-2.21,;3.6,-1.44,;3.6,.1,;2.26,.87,;.93,.1,;.93,-1.44,;-.4,.87,;-1.74,.1,;-3.07,.87,;-4.4,.1,;-4.4,-1.44,;-5.74,.87,;-7.2,.4,;-8.11,1.64,;-7.2,2.89,;-5.7,2.44,;-4.46,3.34,;-3.21,4.25,;-5.36,4.59,;-3.55,2.1,;-9.65,1.64,;-10.42,.31,;-11.96,.31,;-12.73,1.64,;-14.27,1.64,;-11.96,2.98,;-10.42,2.98,;4.93,.87,;6.27,.1,)| Show InChI InChI=1S/C28H28ClF3N4O4/c29-20-7-11-22(12-8-20)36-16-23(26(35-36)28(30,31)32)27(40)33-14-13-24(37)34-21-9-5-19(6-10-21)18-3-1-17(2-4-18)15-25(38)39/h5-12,16-18H,1-4,13-15H2,(H,33,40)(H,34,37)(H,38,39)/t17-,18? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223511
(US9321728, 51)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2cn(nc2C(F)(F)F)-c2ccccc2Cl)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;$,(13.5,-4.52,;12.16,-3.75,;12.16,-2.21,;10.83,-4.52,;9.5,-3.75,;9.5,-2.21,;8.16,-1.44,;6.83,-2.21,;6.83,-3.75,;8.16,-4.52,;5.5,-1.44,;4.16,-2.21,;2.83,-1.44,;2.83,.1,;1.49,.87,;.16,.1,;.16,-1.44,;-1.17,.87,;-2.51,.1,;-3.84,.87,;-5.17,.1,;-5.17,-1.44,;-6.51,.87,;-7.97,.4,;-8.88,1.64,;-7.97,2.89,;-6.47,2.44,;-5.23,3.34,;-3.98,4.25,;-6.13,4.59,;-4.32,2.1,;-10.42,1.64,;-11.19,.31,;-12.73,.31,;-13.5,1.64,;-12.73,2.98,;-11.19,2.98,;-10.42,4.31,;4.16,.87,;5.5,.1,)| Show InChI InChI=1S/C28H28ClF3N4O4/c29-22-3-1-2-4-23(22)36-16-21(26(35-36)28(30,31)32)27(40)33-14-13-24(37)34-20-11-9-19(10-12-20)18-7-5-17(6-8-18)15-25(38)39/h1-4,9-12,16-18H,5-8,13-15H2,(H,33,40)(H,34,37)(H,38,39)/t17-,18? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223505
(US9321728, 31)Show SMILES Cc1oc(nc1C(=O)NCCC(=O)Nc1ccc(cc1)C1CC[C@H](CC(O)=O)CC1)-c1ccccc1 |r,wD:23.25,$;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;$,(-5.17,3.85,;-6.51,3.08,;-7.97,3.56,;-8.88,2.31,;-7.97,1.06,;-6.51,1.54,;-5.17,.77,;-5.17,-.77,;-3.84,1.54,;-2.51,.77,;-1.17,1.54,;.16,.77,;.16,-.77,;1.49,1.54,;2.83,.77,;2.83,-.77,;4.16,-1.54,;5.5,-.77,;5.5,.77,;4.16,1.54,;6.83,-1.54,;8.16,-.77,;9.5,-1.54,;9.5,-3.08,;10.83,-3.85,;12.16,-3.08,;13.5,-3.85,;12.16,-1.54,;8.16,-3.85,;6.83,-3.08,;-10.42,2.31,;-11.19,3.64,;-12.73,3.64,;-13.5,2.31,;-12.73,.98,;-11.19,.98,)| Show InChI InChI=1S/C28H31N3O5/c1-18-26(31-28(36-18)22-5-3-2-4-6-22)27(35)29-16-15-24(32)30-23-13-11-21(12-14-23)20-9-7-19(8-10-20)17-25(33)34/h2-6,11-14,19-20H,7-10,15-17H2,1H3,(H,29,35)(H,30,32)(H,33,34)/t19-,20? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223501
(US9321728, 19)Show SMILES Cc1ccc(cc1)-c1nc(C(=O)NCCC(=O)Nc2ccc(cc2)C2CC[C@H](CC(O)=O)CC2)c(o1)C(F)(F)F |r,wD:27.29,$;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;$,(-14.27,1.64,;-12.73,1.64,;-11.96,.31,;-10.42,.31,;-9.65,1.64,;-10.42,2.98,;-11.96,2.98,;-8.11,1.64,;-7.2,.4,;-5.74,.87,;-4.4,.1,;-4.4,-1.44,;-3.07,.87,;-1.74,.1,;-.4,.87,;.93,.1,;.93,-1.44,;2.26,.87,;3.6,.1,;3.6,-1.44,;4.93,-2.21,;6.27,-1.44,;6.27,.1,;4.93,.87,;7.6,-2.21,;8.93,-1.44,;10.27,-2.21,;10.27,-3.75,;11.6,-4.52,;12.93,-3.75,;14.27,-4.52,;12.93,-2.21,;8.93,-4.52,;7.6,-3.75,;-5.7,2.44,;-7.2,2.89,;-4.46,3.34,;-3.21,4.25,;-5.36,4.59,;-3.55,2.1,)| Show InChI InChI=1S/C29H30F3N3O5/c1-17-2-6-21(7-3-17)28-35-25(26(40-28)29(30,31)32)27(39)33-15-14-23(36)34-22-12-10-20(11-13-22)19-8-4-18(5-9-19)16-24(37)38/h2-3,6-7,10-13,18-19H,4-5,8-9,14-16H2,1H3,(H,33,39)(H,34,36)(H,37,38)/t18-,19? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223504
(US9321728, 27)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccc(Br)cc2)cc1 |r,wD:4.3,(12.93,2.21,;12.93,3.75,;14.27,4.52,;11.6,4.52,;10.27,3.75,;8.93,4.52,;7.6,3.75,;7.6,2.21,;8.93,1.44,;10.27,2.21,;6.27,1.44,;4.93,2.21,;3.6,1.44,;3.6,-.1,;2.26,-.87,;.93,-.1,;.93,1.44,;-.4,-.87,;-1.74,-.1,;-3.07,-.87,;-4.4,-.1,;-4.4,1.44,;-5.74,-.87,;-7.2,-.4,;-8.11,-1.64,;-7.2,-2.89,;-5.65,-2.43,;-4.39,-3.32,;-3.13,-4.21,;-5.27,-4.58,;-3.5,-2.06,;-9.65,-1.64,;-10.42,-.31,;-11.96,-.31,;-12.73,-1.64,;-14.27,-1.64,;-11.96,-2.98,;-10.42,-2.98,;4.93,-.87,;6.27,-.1,)| Show InChI InChI=1S/C28H27BrF3N3O5/c29-20-9-5-19(6-10-20)27-35-24(25(40-27)28(30,31)32)26(39)33-14-13-22(36)34-21-11-7-18(8-12-21)17-3-1-16(2-4-17)15-23(37)38/h5-12,16-17H,1-4,13-15H2,(H,33,39)(H,34,36)(H,37,38)/t16-,17? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223521
(US9321728, 75)Show SMILES Cc1cccc(C)c1-c1ccc(cc1)C(=O)NCCC(=O)Nc1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:31.34,$;;;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;$,(-9.34,5.01,;-10.67,4.24,;-12,5.01,;-13.34,4.24,;-13.34,2.7,;-12,1.93,;-12,.39,;-10.67,2.7,;-9.34,1.93,;-8,2.7,;-6.67,1.93,;-6.67,.39,;-8,-.39,;-9.34,.39,;-5.33,-.39,;-5.33,-1.93,;-4,.39,;-2.67,-.39,;-1.33,.39,;,-.39,;,-1.93,;1.33,.39,;2.67,-.39,;2.67,-1.93,;4,-2.7,;5.33,-1.93,;5.33,-.39,;4,.39,;6.67,-2.7,;8,-1.93,;9.34,-2.7,;9.34,-4.24,;10.67,-5.01,;12,-4.24,;13.34,-5.01,;12,-2.7,;8,-5.01,;6.67,-4.24,)| Show InChI InChI=1S/C32H36N2O4/c1-21-4-3-5-22(2)31(21)26-10-12-27(13-11-26)32(38)33-19-18-29(35)34-28-16-14-25(15-17-28)24-8-6-23(7-9-24)20-30(36)37/h3-5,10-17,23-24H,6-9,18-20H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)/t23-,24? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223506
(US9321728, 33)Show SMILES Cc1nc(sc1C(=O)NCCC(=O)Nc1ccc(cc1)C1CC[C@H](CC(O)=O)CC1)-c1ccccc1 |r,wD:23.25,$;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;$,(-5.25,3.85,;-6.59,3.08,;-8.05,3.56,;-8.96,2.31,;-8.05,1.06,;-6.59,1.54,;-5.25,.77,;-5.25,-.77,;-3.92,1.54,;-2.59,.77,;-1.25,1.54,;.08,.77,;.08,-.77,;1.42,1.54,;2.75,.77,;2.75,-.77,;4.08,-1.54,;5.42,-.77,;5.42,.77,;4.08,1.54,;6.75,-1.54,;8.08,-.77,;9.42,-1.54,;9.42,-3.08,;10.75,-3.85,;12.09,-3.08,;13.42,-3.85,;12.09,-1.54,;8.08,-3.85,;6.75,-3.08,;-10.44,1.91,;-11.53,3,;-13.02,2.6,;-13.42,1.11,;-12.33,.03,;-10.84,.42,)| Show InChI InChI=1S/C28H31N3O4S/c1-18-26(36-28(30-18)22-5-3-2-4-6-22)27(35)29-16-15-24(32)31-23-13-11-21(12-14-23)20-9-7-19(8-10-20)17-25(33)34/h2-6,11-14,19-20H,7-10,15-17H2,1H3,(H,29,35)(H,31,32)(H,33,34)/t19-,20? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223503
(US9321728, 22)Show SMILES FC(F)(F)c1oc(nc1C(=O)NCCC(=O)Nc1ccc(cc1)C1CC[C@H](CC(=O)O[Na])CC1)-c1ccccc1 |r,wU:26.28,$;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;$,(-9.29,-2.88,;-8.97,-1.38,;-10.47,-1.06,;-7.46,-1.7,;-8.65,.13,;-9.68,1.27,;-8.91,2.61,;-7.4,2.29,;-7.24,.76,;-5.91,-.01,;-5.91,-1.55,;-4.57,.76,;-3.24,-.01,;-1.9,.76,;-.57,-.01,;-.57,-1.55,;.76,.76,;2.1,-.01,;3.43,.76,;4.76,-.01,;4.76,-1.55,;3.43,-2.32,;2.1,-1.55,;6.1,-2.32,;6.1,-3.86,;7.43,-4.63,;8.76,-3.86,;10.1,-4.63,;11.43,-3.86,;11.43,-2.32,;12.77,-4.63,;14.1,-3.86,;8.76,-2.32,;7.43,-1.55,;-9.53,4.02,;-8.63,5.26,;-9.25,6.67,;-10.79,6.83,;-11.69,5.58,;-11.06,4.18,)| Show InChI InChI=1S/C28H28F3N3O5.Na/c29-28(30,31)25-24(34-27(39-25)20-4-2-1-3-5-20)26(38)32-15-14-22(35)33-21-12-10-19(11-13-21)18-8-6-17(7-9-18)16-23(36)37;/h1-5,10-13,17-18H,6-9,14-16H2,(H,32,38)(H,33,35)(H,36,37);/q;+1/p-1/t17-,18?; | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223513
(US9321728, 58)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2ccc(OCC3CC3)cc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;$,(14.11,-4.52,;12.77,-3.75,;12.77,-2.21,;11.44,-4.52,;10.11,-3.75,;10.11,-2.21,;8.77,-1.44,;7.44,-2.21,;7.44,-3.75,;8.77,-4.52,;6.1,-1.44,;4.77,-2.21,;3.44,-1.44,;3.44,.1,;2.1,.87,;.77,.1,;.77,-1.44,;-.56,.87,;-1.9,.1,;-3.23,.87,;-4.56,.1,;-4.56,-1.44,;-5.9,.87,;-7.23,.1,;-8.57,.87,;-8.57,2.41,;-9.9,3.18,;-11.23,2.41,;-12.57,3.18,;-14.11,3.18,;-13.34,4.52,;-7.23,3.18,;-5.9,2.41,;4.77,.87,;6.1,.1,)| Show InChI InChI=1S/C28H34N2O5/c31-26(15-16-29-28(34)23-9-13-25(14-10-23)35-18-20-1-2-20)30-24-11-7-22(8-12-24)21-5-3-19(4-6-21)17-27(32)33/h7-14,19-21H,1-6,15-18H2,(H,29,34)(H,30,31)(H,32,33)/t19-,21? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM223512
(US9321728, 56)Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2nc(oc2C(F)(F)F)-c2ccc(F)cc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;;;;$,(14.27,-4.52,;12.93,-3.75,;12.93,-2.21,;11.6,-4.52,;10.27,-3.75,;10.27,-2.21,;8.93,-1.44,;7.6,-2.21,;7.6,-3.75,;8.93,-4.52,;6.27,-1.44,;4.93,-2.21,;3.6,-1.44,;3.6,.1,;2.26,.87,;.93,.1,;.93,-1.44,;-.4,.87,;-1.74,.1,;-3.07,.87,;-4.4,.1,;-4.4,-1.44,;-5.74,.87,;-7.2,.4,;-8.11,1.64,;-7.2,2.89,;-5.7,2.44,;-4.46,3.34,;-3.21,4.25,;-5.36,4.59,;-3.55,2.1,;-9.65,1.64,;-10.42,.31,;-11.96,.31,;-12.73,1.64,;-14.27,1.64,;-11.96,2.98,;-10.42,2.98,;4.93,.87,;6.27,.1,)| Show InChI InChI=1S/C28H27F4N3O5/c29-20-9-5-19(6-10-20)27-35-24(25(40-27)28(30,31)32)26(39)33-14-13-22(36)34-21-11-7-18(8-12-21)17-3-1-16(2-4-17)15-23(37)38/h5-12,16-17H,1-4,13-15H2,(H,33,39)(H,34,36)(H,37,38)/t16-,17? | PDB
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KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD.
US Patent
| Assay Description
Human DGAT-1 activity was determined as follows: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2, 0.04% BSA] containing 500 μM of enzyme substr... |
US Patent US9321728 (2016)
BindingDB Entry DOI: 10.7270/Q2FX789Z |
More data for this
Ligand-Target Pair | |
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