Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227471 (US9334268, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227465 (US9334268, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM60954 (US9334268, 1-[2-(2-Aminoethoxy)ethyl]-2-(ethoxymet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227466 (US9334268, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227472 (US9334268, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 256 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227463 (US9334268, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 223 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227464 (US9334268, 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227471 (US9334268, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 139 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227475 (US9334268, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM60954 (US9334268, 1-[2-(2-Aminoethoxy)ethyl]-2-(ethoxymet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227459 (US9334268, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 580 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227465 (US9334268, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227479 (US9334268, 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227478 (US9334268, 10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 152 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | PDB US Patent | n/a | n/a | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227466 (US9334268, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 195 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227479 (US9334268, 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227463 (US9334268, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | PDB US Patent | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227459 (US9334268, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227472 (US9334268, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 134 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227462 (US9334268, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 80 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227475 (US9334268, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 54 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM227478 (US9334268, 10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM227462 (US9334268, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo... | US Patent US9334268 (2016) BindingDB Entry DOI: 10.7270/Q2SX6C37 | |||||||||||
More data for this Ligand-Target Pair |