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Patent code US9345700

Compile Data Set for Download or QSAR
Found 53 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231614
PNG
(US9345700, 49)
Show SMILES COC(=O)C1CCN(CC1)C(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C28H23N3O4S/c1-34-28(33)17-8-10-31(11-9-17)27(32)21-15-23(25-3-2-12-35-25)30-22-6-4-18(13-20(21)22)19-5-7-26-24(14-19)29-16-36-26/h2-7,12-17H,8-11H2,1H3
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US Patent
n/an/a 600n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231592
PNG
(US9345700, 27)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(NCCNc3ccccc3)cc12)-c1ccco1
Show InChI InChI=1S/C27H23N5O2/c33-27(31-21-8-4-12-28-18-21)23-17-25(26-9-5-15-34-26)32-24-11-10-20(16-22(23)24)30-14-13-29-19-6-2-1-3-7-19/h1-12,15-18,29-30H,13-14H2,(H,31,33)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231587
PNG
(US9345700, 22)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2ncccc2c1)-c1ccco1
Show InChI InChI=1S/C28H18N4O2/c33-28(31-21-5-2-11-29-17-21)23-16-26(27-6-3-13-34-27)32-25-10-8-19(15-22(23)25)18-7-9-24-20(14-18)4-1-12-30-24/h1-17H,(H,31,33)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231584
PNG
(US9345700, 19)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2ccccc2c1)-c1ccco1
Show InChI InChI=1S/C29H19N3O2/c33-29(31-23-7-3-13-30-18-23)25-17-27(28-8-4-14-34-28)32-26-12-11-22(16-24(25)26)21-10-9-19-5-1-2-6-20(19)15-21/h1-18H,(H,31,33)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231591
PNG
(US9345700, 26)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2[nH]cnc2c1)-c1ccco1
Show InChI InChI=1S/C26H17N5O2/c32-26(30-18-3-1-9-27-14-18)20-13-24(25-4-2-10-33-25)31-21-7-5-16(11-19(20)21)17-6-8-22-23(12-17)29-15-28-22/h1-15H,(H,28,29)(H,30,32)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231571
PNG
(US9345700, 6)
Show SMILES COc1cccc(c1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C26H19N3O3/c1-31-20-7-2-5-17(13-20)18-9-10-23-21(14-18)22(15-24(29-23)25-8-4-12-32-25)26(30)28-19-6-3-11-27-16-19/h2-16H,1H3,(H,28,30)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231572
PNG
(US9345700, 7)
Show SMILES COc1ccc(cc1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C26H19N3O3/c1-31-20-9-6-17(7-10-20)18-8-11-23-21(14-18)22(15-24(29-23)25-5-3-13-32-25)26(30)28-19-4-2-12-27-16-19/h2-16H,1H3,(H,28,30)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231594
PNG
(US9345700, 29)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2ccccc2n1)-c1ccco1
Show InChI InChI=1S/C28H18N4O2/c33-28(30-20-6-3-13-29-17-20)22-16-26(27-8-4-14-34-27)32-25-12-10-19(15-21(22)25)24-11-9-18-5-1-2-7-23(18)31-24/h1-17H,(H,30,33)
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Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231583
PNG
(US9345700, 18)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C26H16N4O2S/c31-26(29-18-3-1-9-27-14-18)20-13-22(24-4-2-10-32-24)30-21-7-5-16(11-19(20)21)17-6-8-25-23(12-17)28-15-33-25/h1-15H,(H,29,31)
PDB
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n/an/a 1.70E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231597
PNG
(US9345700, 32)
Show SMILES CNC(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C22H15N3O2S/c1-23-22(26)16-11-18(20-3-2-8-27-20)25-17-6-4-13(9-15(16)17)14-5-7-21-19(10-14)24-12-28-21/h2-12H,1H3,(H,23,26)
PDB
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n/an/a 1.80E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231605
PNG
(US9345700, 40)
Show SMILES O=C(NC1CC1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C24H17N3O2S/c28-24(26-16-5-6-16)18-12-20(22-2-1-9-29-22)27-19-7-3-14(10-17(18)19)15-4-8-23-21(11-15)25-13-30-23/h1-4,7-13,16H,5-6H2,(H,26,28)
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Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231586
PNG
(US9345700, 21)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2[nH]c(=O)[nH]c2c1)-c1ccco1
Show InChI InChI=1S/C26H17N5O3/c32-25(28-17-3-1-9-27-14-17)19-13-23(24-4-2-10-34-24)29-20-7-5-15(11-18(19)20)16-6-8-21-22(12-16)31-26(33)30-21/h1-14H,(H,28,32)(H2,30,31,33)
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Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231569
PNG
(US9345700, 4)
Show SMILES Fc1cccc(c1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C25H16FN3O2/c26-18-5-1-4-16(12-18)17-8-9-22-20(13-17)21(14-23(29-22)24-7-3-11-31-24)25(30)28-19-6-2-10-27-15-19/h1-15H,(H,28,30)
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n/an/a 1.90E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231603
PNG
(US9345700, 38)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1cn[nH]c1
Show InChI InChI=1S/C24H17N5O/c30-24(28-19-7-4-10-25-15-19)21-12-23(18-13-26-27-14-18)29-22-9-8-17(11-20(21)22)16-5-2-1-3-6-16/h1-15H,(H,26,27)(H,28,30)
PDB
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n/an/a 2.00E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231582
PNG
(US9345700, 17)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2[nH]ncc2c1)-c1ccco1
Show InChI InChI=1S/C26H17N5O2/c32-26(29-19-3-1-9-27-15-19)21-13-24(25-4-2-10-33-25)30-23-8-6-17(12-20(21)23)16-5-7-22-18(11-16)14-28-31-22/h1-15H,(H,28,31)(H,29,32)
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Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231618
PNG
(US9345700, 53)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ncco1
Show InChI InChI=1S/C25H15N5O2S/c31-24(29-17-2-1-7-26-13-17)19-12-22(25-27-8-9-32-25)30-20-5-3-15(10-18(19)20)16-4-6-23-21(11-16)28-14-33-23/h1-14H,(H,29,31)
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n/an/a 2.20E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231581
PNG
(US9345700, 16)
Show SMILES Cn1cnc2cc(ccc12)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C27H19N5O2/c1-32-16-29-23-13-18(7-9-25(23)32)17-6-8-22-20(12-17)21(14-24(31-22)26-5-3-11-34-26)27(33)30-19-4-2-10-28-15-19/h2-16H,1H3,(H,30,33)
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n/an/a 2.20E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231606
PNG
(US9345700, 41)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1nccs1
Show InChI InChI=1S/C24H16N4OS/c29-23(27-18-7-4-10-25-15-18)20-14-22(24-26-11-12-30-24)28-21-9-8-17(13-19(20)21)16-5-2-1-3-6-16/h1-15H,(H,27,29)
PDB
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n/an/a 2.40E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231580
PNG
(US9345700, 15)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2cc[nH]c2c1)-c1ccco1
Show InChI InChI=1S/C27H18N4O2/c32-27(30-20-3-1-10-28-16-20)22-15-25(26-4-2-12-33-26)31-23-8-7-18(13-21(22)23)19-6-5-17-9-11-29-24(17)14-19/h1-16,29H,(H,30,32)
PDB
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n/an/a 2.40E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231617
PNG
(US9345700, 52)
Show SMILES CNC(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ncco1
Show InChI InChI=1S/C21H14N4O2S/c1-22-20(26)15-10-18(21-23-6-7-27-21)25-16-4-2-12(8-14(15)16)13-3-5-19-17(9-13)24-11-28-19/h2-11H,1H3,(H,22,26)
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US Patent
n/an/a 2.50E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231609
PNG
(US9345700, 44)
Show SMILES O=C(Nc1ccncc1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C26H16N4O2S/c31-26(29-18-7-9-27-10-8-18)20-14-22(24-2-1-11-32-24)30-21-5-3-16(12-19(20)21)17-4-6-25-23(13-17)28-15-33-25/h1-15H,(H,27,29,31)
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n/an/a 2.60E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231608
PNG
(US9345700, 43)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1ncco1
Show InChI InChI=1S/C24H16N4O2/c29-23(27-18-7-4-10-25-15-18)20-14-22(24-26-11-12-30-24)28-21-9-8-17(13-19(20)21)16-5-2-1-3-6-16/h1-15H,(H,27,29)
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n/an/a 2.60E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231585
PNG
(US9345700, 20)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1c[nH]c2ccccc12)-c1ccco1
Show InChI InChI=1S/C27H18N4O2/c32-27(30-18-5-3-11-28-15-18)21-14-25(26-8-4-12-33-26)31-24-10-9-17(13-20(21)24)22-16-29-23-7-2-1-6-19(22)23/h1-16,29H,(H,30,32)
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n/an/a 2.80E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231588
PNG
(US9345700, 23)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccn1)-c1ccco1
Show InChI InChI=1S/C24H16N4O2/c29-24(27-17-5-3-10-25-15-17)19-14-22(23-7-4-12-30-23)28-21-9-8-16(13-18(19)21)20-6-1-2-11-26-20/h1-15H,(H,27,29)
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n/an/a 2.80E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231566
PNG
(US9345700, 1)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1ccco1
Show InChI InChI=1S/C25H17N3O2/c29-25(27-19-8-4-12-26-16-19)21-15-23(24-9-5-13-30-24)28-22-11-10-18(14-20(21)22)17-6-2-1-3-7-17/h1-16H,(H,27,29)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231598
PNG
(US9345700, 33)
Show SMILES O=C(Nc1ccccc1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C27H17N3O2S/c31-27(29-19-5-2-1-3-6-19)21-15-23(25-7-4-12-32-25)30-22-10-8-17(13-20(21)22)18-9-11-26-24(14-18)28-16-33-26/h1-16H,(H,29,31)
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n/an/a 3.20E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231602
PNG
(US9345700, 37)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1cnn(c1)C1CCCCO1
Show InChI InChI=1S/C29H25N5O2/c35-29(32-23-9-6-13-30-18-23)25-16-27(22-17-31-34(19-22)28-10-4-5-14-36-28)33-26-12-11-21(15-24(25)26)20-7-2-1-3-8-20/h1-3,6-9,11-13,15-19,28H,4-5,10,14H2,(H,32,35)
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n/an/a 3.30E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231613
PNG
(US9345700, 48)
Show SMILES CN(C(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1)c1cccnc1
Show InChI InChI=1S/C27H18N4O2S/c1-31(19-4-2-10-28-15-19)27(32)21-14-23(25-5-3-11-33-25)30-22-8-6-17(12-20(21)22)18-7-9-26-24(13-18)29-16-34-26/h2-16H,1H3
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n/an/a 3.30E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231612
PNG
(US9345700, 47)
Show SMILES O=C(Nc1ccccn1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C26H16N4O2S/c31-26(30-25-5-1-2-10-27-25)19-14-21(23-4-3-11-32-23)29-20-8-6-16(12-18(19)20)17-7-9-24-22(13-17)28-15-33-24/h1-15H,(H,27,30,31)
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Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231574
PNG
(US9345700, 9)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1cccc(c1)-c1ccccc1)-c1ccco1
Show InChI InChI=1S/C31H21N3O2/c35-31(33-25-11-5-15-32-20-25)27-19-29(30-12-6-16-36-30)34-28-14-13-24(18-26(27)28)23-10-4-9-22(17-23)21-7-2-1-3-8-21/h1-20H,(H,33,35)
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n/an/a 3.70E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231590
PNG
(US9345700, 25)
Show SMILES CN(CCNc1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1)Cc1ccccc1
Show InChI InChI=1S/C29H27N5O2/c1-34(20-21-7-3-2-4-8-21)15-14-31-22-11-12-26-24(17-22)25(18-27(33-26)28-10-6-16-36-28)29(35)32-23-9-5-13-30-19-23/h2-13,16-19,31H,14-15,20H2,1H3,(H,32,35)
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n/an/a 3.80E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231615
PNG
(US9345700, 50)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)N1CCN(CC1)c1ccccc1)-c1ccco1
Show InChI InChI=1S/C29H25N5O2/c35-29(31-21-6-4-12-30-20-21)25-19-27(28-9-5-17-36-28)32-26-11-10-23(18-24(25)26)34-15-13-33(14-16-34)22-7-2-1-3-8-22/h1-12,17-20H,13-16H2,(H,31,35)
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n/an/a 4.60E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231610
PNG
(US9345700, 45)
Show SMILES O=C(Nc1nc2ccccc2s1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C28H16N4O2S2/c33-27(32-28-31-21-4-1-2-6-26(21)36-28)19-14-22(24-5-3-11-34-24)30-20-9-7-16(12-18(19)20)17-8-10-25-23(13-17)29-15-35-25/h1-15H,(H,31,32,33)
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n/an/a 4.80E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231595
PNG
(US9345700, 30)
Show SMILES Cc1ccc(o1)-c1cc(C(=O)Nc2cccnc2)c2cc(ccc2n1)-c1ccccc1
Show InChI InChI=1S/C26H19N3O2/c1-17-9-12-25(31-17)24-15-22(26(30)28-20-8-5-13-27-16-20)21-14-19(10-11-23(21)29-24)18-6-3-2-4-7-18/h2-16H,1H3,(H,28,30)
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n/an/a 4.90E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231616
PNG
(US9345700, 51)
Show SMILES O=C(Nc1nc2ccccc2[nH]1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C28H17N5O2S/c34-27(33-28-31-21-4-1-2-5-22(21)32-28)19-14-23(25-6-3-11-35-25)30-20-9-7-16(12-18(19)20)17-8-10-26-24(13-17)29-15-36-26/h1-15H,(H2,31,32,33,34)
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n/an/a 4.90E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231570
PNG
(US9345700, 5)
Show SMILES Fc1ccc(cc1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C25H16FN3O2/c26-18-8-5-16(6-9-18)17-7-10-22-20(13-17)21(14-23(29-22)24-4-2-12-31-24)25(30)28-19-3-1-11-27-15-19/h1-15H,(H,28,30)
PDB
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n/an/a 5.00E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231599
PNG
(US9345700, 34)
Show SMILES Cc1nn(C)cc1-c1cc(C(=O)Nc2cccnc2)c2cc(ccc2n1)-c1ccccc1
Show InChI InChI=1S/C26H21N5O/c1-17-23(16-31(2)30-17)25-14-22(26(32)28-20-9-6-12-27-15-20)21-13-19(10-11-24(21)29-25)18-7-4-3-5-8-18/h3-16H,1-2H3,(H,28,32)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231579
PNG
(US9345700, 14)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccncc1)-c1ccco1
Show InChI InChI=1S/C24H16N4O2/c29-24(27-18-3-1-9-26-15-18)20-14-22(23-4-2-12-30-23)28-21-6-5-17(13-19(20)21)16-7-10-25-11-8-16/h1-15H,(H,27,29)
PDB
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n/an/a 5.10E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231611
PNG
(US9345700, 46)
Show SMILES COC(=O)C1CCCN(C1)C(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C28H23N3O4S/c1-34-28(33)19-4-2-10-31(15-19)27(32)21-14-23(25-5-3-11-35-25)30-22-8-6-17(12-20(21)22)18-7-9-26-24(13-18)29-16-36-26/h3,5-9,11-14,16,19H,2,4,10,15H2,1H3
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n/an/a 5.30E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231577
PNG
(US9345700, 12)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1cccc(Oc2ccccc2)c1)-c1ccco1
Show InChI InChI=1S/C31H21N3O3/c35-31(33-23-8-5-15-32-20-23)27-19-29(30-12-6-16-36-30)34-28-14-13-22(18-26(27)28)21-7-4-11-25(17-21)37-24-9-2-1-3-10-24/h1-20H,(H,33,35)
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US Patent
n/an/a 6.30E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231607
PNG
(US9345700, 42)
Show SMILES O=C(NC1CCCCC1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C27H23N3O2S/c31-27(29-19-5-2-1-3-6-19)21-15-23(25-7-4-12-32-25)30-22-10-8-17(13-20(21)22)18-9-11-26-24(14-18)28-16-33-26/h4,7-16,19H,1-3,5-6H2,(H,29,31)
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US Patent
n/an/a 6.40E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231578
PNG
(US9345700, 13)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc(Oc2ccccc2)cc1)-c1ccco1
Show InChI InChI=1S/C31H21N3O3/c35-31(33-23-6-4-16-32-20-23)27-19-29(30-9-5-17-36-30)34-28-15-12-22(18-26(27)28)21-10-13-25(14-11-21)37-24-7-2-1-3-8-24/h1-20H,(H,33,35)
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n/an/a 7.20E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231601
PNG
(US9345700, 36)
Show SMILES Cn1cc(cn1)-c1cc(C(=O)Nc2cccnc2)c2cc(ccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H19N5O/c1-30-16-19(14-27-30)24-13-22(25(31)28-20-8-5-11-26-15-20)21-12-18(9-10-23(21)29-24)17-6-3-2-4-7-17/h2-16H,1H3,(H,28,31)
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n/an/a 7.30E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231575
PNG
(US9345700, 10)
Show SMILES COCCOc1cccc(c1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C28H23N3O4/c1-33-13-14-34-22-7-2-5-19(15-22)20-9-10-25-23(16-20)24(17-26(31-25)27-8-4-12-35-27)28(32)30-21-6-3-11-29-18-21/h2-12,15-18H,13-14H2,1H3,(H,30,32)
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n/an/a 7.60E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231573
PNG
(US9345700, 8)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc(cc1)-c1ccccc1)-c1ccco1
Show InChI InChI=1S/C31H21N3O2/c35-31(33-25-8-4-16-32-20-25)27-19-29(30-9-5-17-36-30)34-28-15-14-24(18-26(27)28)23-12-10-22(11-13-23)21-6-2-1-3-7-21/h1-20H,(H,33,35)
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n/an/a 7.70E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231567
PNG
(US9345700, 2)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1cn[nH]c1)-c1ccco1
Show InChI InChI=1S/C22H15N5O2/c28-22(26-16-3-1-7-23-13-16)18-10-20(21-4-2-8-29-21)27-19-6-5-14(9-17(18)19)15-11-24-25-12-15/h1-13H,(H,24,25)(H,26,28)
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n/an/a 8.20E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231568
PNG
(US9345700, 3)
Show SMILES Fc1ccccc1-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C25H16FN3O2/c26-21-7-2-1-6-18(21)16-9-10-22-19(13-16)20(14-23(29-22)24-8-4-12-31-24)25(30)28-17-5-3-11-27-15-17/h1-15H,(H,28,30)
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n/an/a 8.40E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231589
PNG
(US9345700, 24)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(Nc3ccccn3)cc12)-c1ccco1
Show InChI InChI=1S/C24H17N5O2/c30-24(28-17-5-3-10-25-15-17)19-14-21(22-6-4-12-31-22)29-20-9-8-16(13-18(19)20)27-23-7-1-2-11-26-23/h1-15H,(H,26,27)(H,28,30)
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n/an/a 8.60E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231604
PNG
(US9345700, 39)
Show SMILES CN1CCN(CC1)C(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1
Show InChI InChI=1S/C26H22N4O2S/c1-29-8-10-30(11-9-29)26(31)20-15-22(24-3-2-12-32-24)28-21-6-4-17(13-19(20)21)18-5-7-25-23(14-18)27-16-33-25/h2-7,12-16H,8-11H2,1H3
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n/an/a 8.60E+3n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231593
PNG
(US9345700, 28)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2[nH]ccc2c1)-c1ccco1
Show InChI InChI=1S/C27H18N4O2/c32-27(30-20-3-1-10-28-16-20)22-15-25(26-4-2-12-33-26)31-24-8-6-18(14-21(22)24)17-5-7-23-19(13-17)9-11-29-23/h1-16,29H,(H,30,32)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231576
PNG
(US9345700, 11)
Show SMILES COCCOc1ccc(cc1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1
Show InChI InChI=1S/C28H23N3O4/c1-33-14-15-34-22-9-6-19(7-10-22)20-8-11-25-23(16-20)24(17-26(31-25)27-5-3-13-35-27)28(32)30-21-4-2-12-29-18-21/h2-13,16-18H,14-15H2,1H3,(H,30,32)
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n/an/a 1.13E+4n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231596
PNG
(US9345700, 31)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1cc2ccccc2o1
Show InChI InChI=1S/C29H19N3O2/c33-29(31-22-10-6-14-30-18-22)24-17-26(28-16-21-9-4-5-11-27(21)34-28)32-25-13-12-20(15-23(24)25)19-7-2-1-3-8-19/h1-18H,(H,31,33)
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n/an/a 1.23E+4n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM231600
PNG
(US9345700, 35)
Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(NCCOc3ccccc3)cc12)-c1ccco1
Show InChI InChI=1S/C27H22N4O3/c32-27(30-20-6-4-12-28-18-20)23-17-25(26-9-5-14-34-26)31-24-11-10-19(16-22(23)24)29-13-15-33-21-7-2-1-3-8-21/h1-12,14,16-18,29H,13,15H2,(H,30,32)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Eutropics Pharmaceuticals, Inc.

US Patent


Assay Description
A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...

US Patent US9345700 (2016)


BindingDB Entry DOI: 10.7270/Q2J38RD4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%