Affinity Data by Patent

Patent code US9394291

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238166 (US10017502, Example 7 \| US9394291, 7) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238167 (US10017502, Example 8 \| US9394291, 8 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238163 (US10017502, Example 6 \| US9394291, 6 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238161 (US10017502, Example 5a \| US9394291, 5a) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238167 (US10017502, Example 8 \| US9394291, 8 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238163 (US10017502, Example 6 \| US9394291, 6 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238163 (US10017502, Example 6 \| US9394291, 6 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238159 (US10017502, Example 4b \| US9394291, 4a) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238158 (US10017502, Example 4 \| US9394291, 4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238152 (US10017502, Example 2 \| US9394291, 2 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238159 (US10017502, Example 4b \| US9394291, 4a) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238155 (US10017502, Example 3 \| US9394291, 3 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238155 (US10017502, Example 3 \| US9394291, 3 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238158 (US10017502, Example 4 \| US9394291, 4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	740	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238151 (US10017502, Example 1 \| US9394291, 1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238167 (US10017502, Example 8 \| US9394291, 8 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238152 (US10017502, Example 2 \| US9394291, 2 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238163 (US10017502, Example 6 \| US9394291, 6 \| US9394291, ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238151 (US10017502, Example 1 \| US9394291, 1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair
Mineralocorticoid receptor [729-984] (Homo sapiens (Human))	BDBM238162 (US10017502, Example 5b \| US9394291, 5b) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...				US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS
AstraZeneca AB US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%