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Patent code US9409866

Compile Data Set for Download or QSAR

Found 620 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240289
PNG
(US9409866, 4)
Show SMILES NC(=O)[C@H](CC1CC1)NC(=O)c1cc(OCC2CC2)c(Cl)cn1 |r|
Show InChI InChI=1S/C16H20ClN3O3/c17-11-7-19-13(6-14(11)23-8-10-3-4-10)16(22)20-12(15(18)21)5-9-1-2-9/h6-7,9-10,12H,1-5,8H2,(H2,18,21)(H,20,22)/t12-/m0/s1
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n/an/an/an/a 115n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240294
PNG
(US9409866, 9)
Show SMILES CC(C)C[C@H](NC(=O)c1cc(OCC2CC2)c(Br)cn1)C(N)=O |r|
Show InChI InChI=1S/C16H22BrN3O3/c1-9(2)5-12(15(18)21)20-16(22)13-6-14(11(17)7-19-13)23-8-10-3-4-10/h6-7,9-10,12H,3-5,8H2,1-2H3,(H2,18,21)(H,20,22)/t12-/m0/s1
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n/an/an/an/a 32.9n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240312
PNG
(US9409866, 27)
Show SMILES CC(C)C[C@@](C)(CO)NC(=O)c1cc(OCC2CC2)c(Cl)cn1 |r|
Show InChI InChI=1S/C17H25ClN2O3/c1-11(2)7-17(3,10-21)20-16(22)14-6-15(13(18)8-19-14)23-9-12-4-5-12/h6,8,11-12,21H,4-5,7,9-10H2,1-3H3,(H,20,22)/t17-/m0/s1
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n/an/an/an/a 22.4n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240336
PNG
(US9409866, 51)
Show SMILES FC(F)(F)COc1cc(ncc1C1CC1)C(=O)NC(c1ccccn1)C(F)(F)F
Show InChI InChI=1S/C18H15F6N3O2/c19-17(20,21)9-29-14-7-13(26-8-11(14)10-4-5-10)16(28)27-15(18(22,23)24)12-3-1-2-6-25-12/h1-3,6-8,10,15H,4-5,9H2,(H,27,28)
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n/an/an/an/a 12.2n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240339
PNG
(US9409866, 54)
Show SMILES CCC(CC)(CO)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C17H23F3N2O3/c1-3-16(4-2,9-23)22-15(24)13-7-14(25-10-17(18,19)20)12(8-21-13)11-5-6-11/h7-8,11,23H,3-6,9-10H2,1-2H3,(H,22,24)
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n/an/an/an/a 18.5n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240378
PNG
(US9409866, 93)
Show SMILES Cc1nc(no1)[C@@](C)(CC1CC1)NC(=O)c1cc(OCC(F)(F)F)c(Cl)cn1 |r|
Show InChI InChI=1S/C17H18ClF3N4O3/c1-9-23-15(25-28-9)16(2,6-10-3-4-10)24-14(26)12-5-13(11(18)7-22-12)27-8-17(19,20)21/h5,7,10H,3-4,6,8H2,1-2H3,(H,24,26)/t16-/m1/s1
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n/an/an/an/a 65.1n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240379
PNG
(US9409866, 94)
Show SMILES Cc1nc(no1)[C@](C)(CC1CC1)NC(=O)c1cc(OCC(F)(F)F)c(Cl)cn1 |r|
Show InChI InChI=1S/C17H18ClF3N4O3/c1-9-23-15(25-28-9)16(2,6-10-3-4-10)24-14(26)12-5-13(11(18)7-22-12)27-8-17(19,20)21/h5,7,10H,3-4,6,8H2,1-2H3,(H,24,26)/t16-/m0/s1
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n/an/an/an/a 74.7n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240392
PNG
(US9409866, 107)
Show SMILES CCN(C(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(C)(C)C
Show InChI InChI=1S/C17H23F3N2O2/c1-5-22(16(2,3)4)15(23)13-8-14(24-10-17(18,19)20)12(9-21-13)11-6-7-11/h8-9,11H,5-7,10H2,1-4H3
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n/an/an/an/a 82.2n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240395
PNG
(US9409866, 110 | US9409866, 120 | US9409866, 121)
Show SMILES C[C@H](Oc1cc(ncc1C1CCC1)C(=O)NC(C)(CC1CC1)c1noc(C)n1)C(F)(F)F |r|
Show InChI InChI=1S/C22H27F3N4O3/c1-12(22(23,24)25)31-18-9-17(26-11-16(18)15-5-4-6-15)19(30)28-21(3,10-14-7-8-14)20-27-13(2)32-29-20/h9,11-12,14-15H,4-8,10H2,1-3H3,(H,28,30)/t12-,21?/m0/s1
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n/an/an/an/a 0.800n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240399
PNG
(US9409866, 114)
Show SMILES NC(=O)[C@@H]1CC(F)(F)CN1C(=O)c1cc(OCC2CC2)c(cn1)C1CC1 |r|
Show InChI InChI=1S/C18H21F2N3O3/c19-18(20)6-14(16(21)24)23(9-18)17(25)13-5-15(26-8-10-1-2-10)12(7-22-13)11-3-4-11/h5,7,10-11,14H,1-4,6,8-9H2,(H2,21,24)/t14-/m0/s1
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n/an/an/an/a 1.00E+3n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240413
PNG
(US9409866, 128)
Show SMILES Cc1nc(no1)C(C)(CN1CC(F)(F)C1)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C20H22F5N5O3/c1-11-27-17(29-33-11)18(2,7-30-8-19(21,22)9-30)28-16(31)14-5-15(32-10-20(23,24)25)13(6-26-14)12-3-4-12/h5-6,12H,3-4,7-10H2,1-2H3,(H,28,31)
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n/an/an/an/a 65.3n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240417
PNG
(US9409866, 132 | US9409866, 133)
Show SMILES Cc1nc(no1)C(C)(CS(C)(=O)=O)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1(F)COC1
Show InChI InChI=1S/C18H20F4N4O6S/c1-10-24-15(26-32-10)16(2,9-33(3,28)29)25-14(27)12-4-13(31-8-18(20,21)22)11(5-23-12)17(19)6-30-7-17/h4-5H,6-9H2,1-3H3,(H,25,27)
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n/an/an/an/a 568n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240415
PNG
(US9409866, 130 | US9409866, 137 | US9409866, 138)
Show SMILES C[C@H](Oc1cc(ncc1C1(F)CCC1)C(=O)NC(C)(CS(C)(=O)=O)c1noc(C)n1)C(F)(F)F |r|
Show InChI InChI=1S/C20H24F4N4O5S/c1-11(20(22,23)24)32-15-8-14(25-9-13(15)19(21)6-5-7-19)16(29)27-18(3,10-34(4,30)31)17-26-12(2)33-28-17/h8-9,11H,5-7,10H2,1-4H3,(H,27,29)/t11-,18?/m0/s1
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n/an/an/an/a 10.5n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240398
PNG
(US9409866, 113 | US9409866, 140 | US9409866, 141)
Show SMILES Cc1nc(no1)C(C)(CO)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C17H19F3N4O4/c1-9-22-15(24-28-9)16(2,7-25)23-14(26)12-5-13(27-8-17(18,19)20)11(6-21-12)10-3-4-10/h5-6,10,25H,3-4,7-8H2,1-2H3,(H,23,26)
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n/an/an/an/a 511n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240398
PNG
(US9409866, 113 | US9409866, 140 | US9409866, 141)
Show SMILES Cc1nc(no1)C(C)(CO)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C17H19F3N4O4/c1-9-22-15(24-28-9)16(2,7-25)23-14(26)12-5-13(27-8-17(18,19)20)11(6-21-12)10-3-4-10/h5-6,10,25H,3-4,7-8H2,1-2H3,(H,23,26)
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n/an/an/an/a 96.8n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240429
PNG
(US9409866, 144 | US9409866, 169)
Show SMILES C[C@H](Oc1cc(ncc1C1(F)COC1)C(=O)NC(C)(C1CC1)c1noc(C)n1)C(F)(F)F |r|
Show InChI InChI=1S/C20H22F4N4O4/c1-10(20(22,23)24)31-15-6-14(25-7-13(15)19(21)8-30-9-19)16(29)27-18(3,12-4-5-12)17-26-11(2)32-28-17/h6-7,10,12H,4-5,8-9H2,1-3H3,(H,27,29)/t10-,18?/m0/s1
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n/an/an/an/a 14.1n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240430
PNG
(US9409866, 145 | US9409866, 154 | US9409866, 155)
Show SMILES Cc1nc(no1)C(C)(CC1CC1)NC(=O)c1cc(OCC(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C20H24F2N4O3/c1-11-24-19(26-29-11)20(2,8-12-3-4-12)25-18(27)15-7-16(28-10-17(21)22)14(9-23-15)13-5-6-13/h7,9,12-13,17H,3-6,8,10H2,1-2H3,(H,25,27)
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n/an/an/an/a 3.40n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240449
PNG
(US9409866, 164)
Show SMILES C[N]1=NNN=C1C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(C)(C)C |c:4,t:1|
Show InChI InChI=1S/C18H24F3N6O2/c1-17(2,3)14(15-24-25-26-27(15)4)23-16(28)12-7-13(29-9-18(19,20)21)11(8-22-12)10-5-6-10/h7-8,10,14H,5-6,9H2,1-4H3,(H,23,28)(H,24,25,26)
PDB

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n/an/an/an/a 16.8n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240424
PNG
(US9409866, 139 | US9409866, 166 | US9409866, 167)
Show SMILES Cc1nc(no1)C(C)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1(F)COC1)C1CC1
Show InChI InChI=1S/C19H20F4N4O4/c1-10-25-16(27-31-10)17(2,11-3-4-11)26-15(28)13-5-14(30-9-19(21,22)23)12(6-24-13)18(20)7-29-8-18/h5-6,11H,3-4,7-9H2,1-2H3,(H,26,28)
PDB

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n/an/an/an/a 28.1n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240453
PNG
(US9409866, 168)
Show SMILES C[C@H](Oc1cc(ncc1C1(F)COC1)C(=O)N[C@@](C)(C1CC1)c1noc(C)n1)C(F)(F)F |r|
Show InChI InChI=1S/C20H22F4N4O4/c1-10(20(22,23)24)31-15-6-14(25-7-13(15)19(21)8-30-9-19)16(29)27-18(3,12-4-5-12)17-26-11(2)32-28-17/h6-7,10,12H,4-5,8-9H2,1-3H3,(H,27,29)/t10-,18-/m0/s1
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n/an/an/an/a 281n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240460
PNG
(US9409866, 175)
Show SMILES C[C@H](Oc1cc(ncc1C1(F)COC1)C(=O)NC(c1nnc(C)o1)C(C)(C)C)C(F)(F)F |r|
Show InChI InChI=1S/C20H24F4N4O4/c1-10(20(22,23)24)31-14-6-13(25-7-12(14)19(21)8-30-9-19)16(29)26-15(18(3,4)5)17-28-27-11(2)32-17/h6-7,10,15H,8-9H2,1-5H3,(H,26,29)/t10-,15?/m0/s1
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n/an/an/an/a 95.5n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240466
PNG
(US9409866, 181)
Show SMILES CN(C)C(=O)C(C)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)c1noc(C)n1
Show InChI InChI=1S/C19H22F3N5O4/c1-10-24-16(26-31-10)18(2,17(29)27(3)4)25-15(28)13-7-14(30-9-19(20,21)22)12(8-23-13)11-5-6-11/h7-8,11H,5-6,9H2,1-4H3,(H,25,28)
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n/an/an/an/a 2n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240467
PNG
(US9409866, 182)
Show SMILES Cc1nc(no1)C(C)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(=O)N1CCC1
Show InChI InChI=1S/C20H22F3N5O4/c1-11-25-17(27-32-11)19(2,18(30)28-6-3-7-28)26-16(29)14-8-15(31-10-20(21,22)23)13(9-24-14)12-4-5-12/h8-9,12H,3-7,10H2,1-2H3,(H,26,29)
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n/an/an/an/a 5.40n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240458
PNG
(US9409866, 173 | US9409866, 184 | US9409866, 185)
Show SMILES Cc1nnc(o1)C(C)(CC1CC1)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C20H23F3N4O3/c1-11-26-27-18(30-11)19(2,8-12-3-4-12)25-17(28)15-7-16(29-10-20(21,22)23)14(9-24-15)13-5-6-13/h7,9,12-13H,3-6,8,10H2,1-2H3,(H,25,28)
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n/an/an/an/a 85.6n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240458
PNG
(US9409866, 173 | US9409866, 184 | US9409866, 185)
Show SMILES Cc1nnc(o1)C(C)(CC1CC1)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C20H23F3N4O3/c1-11-26-27-18(30-11)19(2,8-12-3-4-12)25-17(28)15-7-16(29-10-20(21,22)23)14(9-24-15)13-5-6-13/h7,9,12-13H,3-6,8,10H2,1-2H3,(H,25,28)
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n/an/an/an/a 30.2n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240434
PNG
(US9409866, 149 | US9409866, 187 | US9409866, 188)
Show SMILES CNC(=O)C(C)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)c1noc(C)n1
Show InChI InChI=1S/C18H20F3N5O4/c1-9-24-15(26-30-9)17(2,16(28)22-3)25-14(27)12-6-13(29-8-18(19,20)21)11(7-23-12)10-4-5-10/h6-7,10H,4-5,8H2,1-3H3,(H,22,28)(H,25,27)
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n/an/an/an/a 416n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240476
PNG
(US9409866, 191)
Show SMILES Cc1nnc(o1)C(C)(CC1COC1)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C20H23F3N4O4/c1-11-26-27-18(31-11)19(2,6-12-8-29-9-12)25-17(28)15-5-16(30-10-20(21,22)23)14(7-24-15)13-3-4-13/h5,7,12-13H,3-4,6,8-10H2,1-2H3,(H,25,28)
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n/an/an/an/a 707n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240477
PNG
(US9409866, 192 | US9409866, 226 | US9409866, 227)
Show SMILES CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)c1noc(N)n1
Show InChI InChI=1S/C18H22F3N5O3/c1-17(2,3)13(14-25-16(22)29-26-14)24-15(27)11-6-12(28-8-18(19,20)21)10(7-23-11)9-4-5-9/h6-7,9,13H,4-5,8H2,1-3H3,(H,24,27)(H2,22,25,26)
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n/an/an/an/a 4.40n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240481
PNG
(US9409866, 196)
Show SMILES CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(=O)N1CCC1
Show InChI InChI=1S/C20H26F3N3O3/c1-19(2,3)16(18(28)26-7-4-8-26)25-17(27)14-9-15(29-11-20(21,22)23)13(10-24-14)12-5-6-12/h9-10,12,16H,4-8,11H2,1-3H3,(H,25,27)
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n/an/an/an/a 1.20n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240483
PNG
(US9409866, 198)
Show SMILES CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(=O)N1CCC11COC1
Show InChI InChI=1S/C22H28F3N3O4/c1-20(2,3)17(19(30)28-7-6-21(28)10-31-11-21)27-18(29)15-8-16(32-12-22(23,24)25)14(9-26-15)13-4-5-13/h8-9,13,17H,4-7,10-12H2,1-3H3,(H,27,29)
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n/an/an/an/a 36.4n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240484
PNG
(US9409866, 199 | US9409866, 239 | US9409866, 240)
Show SMILES C[C@H](Oc1cc(ncc1C1CC1)C(=O)NC(C(N)=O)C(C)(C)C)C(F)(F)F |r|
Show InChI InChI=1S/C18H24F3N3O3/c1-9(18(19,20)21)27-13-7-12(23-8-11(13)10-5-6-10)16(26)24-14(15(22)25)17(2,3)4/h7-10,14H,5-6H2,1-4H3,(H2,22,25)(H,24,26)/t9-,14?/m0/s1
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n/an/an/an/a 7.80n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240486
PNG
(US9409866, 201)
Show SMILES C[C@H](Oc1cc(ncc1C1CC1)C(=O)NC(C(=O)N(C)C)C(C)(C)C)C(F)(F)F |r|
Show InChI InChI=1S/C20H28F3N3O3/c1-11(20(21,22)23)29-15-9-14(24-10-13(15)12-7-8-12)17(27)25-16(19(2,3)4)18(28)26(5)6/h9-12,16H,7-8H2,1-6H3,(H,25,27)/t11-,16?/m0/s1
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n/an/an/an/a 2.40n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240490
PNG
(US9409866, 205 | US9409866, 206)
Show SMILES Cn1nnnc1C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(C)(C)C
Show InChI InChI=1S/C18H23F3N6O2/c1-17(2,3)14(15-24-25-26-27(15)4)23-16(28)12-7-13(29-9-18(19,20)21)11(8-22-12)10-5-6-10/h7-8,10,14H,5-6,9H2,1-4H3,(H,23,28)
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n/an/an/an/a 39.3n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240450
PNG
(US9409866, 165 | US9409866, 207 | US9409866, 208)
Show SMILES CC(CC1CC1)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)c1noc(N)n1
Show InChI InChI=1S/C19H22F3N5O3/c1-18(7-10-2-3-10,16-25-17(23)30-27-16)26-15(28)13-6-14(29-9-19(20,21)22)12(8-24-13)11-4-5-11/h6,8,10-11H,2-5,7,9H2,1H3,(H,26,28)(H2,23,25,27)
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n/an/an/an/a 8.30n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240450
PNG
(US9409866, 165 | US9409866, 207 | US9409866, 208)
Show SMILES CC(CC1CC1)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)c1noc(N)n1
Show InChI InChI=1S/C19H22F3N5O3/c1-18(7-10-2-3-10,16-25-17(23)30-27-16)26-15(28)13-6-14(29-9-19(20,21)22)12(8-24-13)11-4-5-11/h6,8,10-11H,2-5,7,9H2,1H3,(H,26,28)(H2,23,25,27)
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n/an/an/an/a 9.20n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240509
PNG
(US9409866, 224 | US9409866, 225)
Show SMILES CNC(=O)C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(C)(C)C
Show InChI InChI=1S/C18H24F3N3O3/c1-17(2,3)14(16(26)22-4)24-15(25)12-7-13(27-9-18(19,20)21)11(8-23-12)10-5-6-10/h7-8,10,14H,5-6,9H2,1-4H3,(H,22,26)(H,24,25)
PDB

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n/an/an/an/a 57.3n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240509
PNG
(US9409866, 224 | US9409866, 225)
Show SMILES CNC(=O)C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(C)(C)C
Show InChI InChI=1S/C18H24F3N3O3/c1-17(2,3)14(16(26)22-4)24-15(25)12-7-13(27-9-18(19,20)21)11(8-23-12)10-5-6-10/h7-8,10,14H,5-6,9H2,1-4H3,(H,22,26)(H,24,25)
PDB

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n/an/an/an/a 0.400n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240520
PNG
(US9409866, 235)
Show SMILES CCC(CC)(NC(=O)c1cc(OCC2(C)COC2)c(cn1)C1CC1)C(=O)NCC(F)CCl
Show InChI InChI=1S/C23H33ClFN3O4/c1-4-23(5-2,21(30)27-10-16(25)9-24)28-20(29)18-8-19(17(11-26-18)15-6-7-15)32-14-22(3)12-31-13-22/h8,11,15-16H,4-7,9-10,12-14H2,1-3H3,(H,27,30)(H,28,29)
PDB

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n/an/an/an/a 293n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240514
PNG
(US9409866, 229 | US9409866, 241 | US9409866, 242)
Show SMILES CNC(=O)CC(C)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C1CC1
Show InChI InChI=1S/C19H24F3N3O3/c1-18(12-5-6-12,8-16(26)23-2)25-17(27)14-7-15(28-10-19(20,21)22)13(9-24-14)11-3-4-11/h7,9,11-12H,3-6,8,10H2,1-2H3,(H,23,26)(H,25,27)
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n/an/an/an/a 11.9n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240515
PNG
(US9409866, 230 | US9409866, 243 | US9409866, 244)
Show SMILES CC(CC(N)=O)(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C1CC1
Show InChI InChI=1S/C18H22F3N3O3/c1-17(7-15(22)25,11-4-5-11)24-16(26)13-6-14(27-9-18(19,20)21)12(8-23-13)10-2-3-10/h6,8,10-11H,2-5,7,9H2,1H3,(H2,22,25)(H,24,26)
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n/an/an/an/a 0.5n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240533
PNG
(US9409866, 248 | US9409866, 258 | US9409866, 259)
Show SMILES C[C@H](Oc1cc(ncc1C1CC1)C(=O)NC(C)(CC(N)=O)C1CC1)C(F)(F)F |r|
Show InChI InChI=1S/C19H24F3N3O3/c1-10(19(20,21)22)28-15-7-14(24-9-13(15)11-3-4-11)17(27)25-18(2,8-16(23)26)12-5-6-12/h7,9-12H,3-6,8H2,1-2H3,(H2,23,26)(H,25,27)/t10-,18?/m0/s1
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n/an/an/an/a 0.900n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240532
PNG
(US9409866, 247 | US9409866, 249 | US9409866, 250)
Show SMILES CNC(=O)CC(C)(NC(=O)c1cc(O[C@@H](C)C(F)(F)F)c(cn1)C1CC1)C1CC1 |r|
Show InChI InChI=1S/C20H26F3N3O3/c1-11(20(21,22)23)29-16-8-15(25-10-14(16)12-4-5-12)18(28)26-19(2,13-6-7-13)9-17(27)24-3/h8,10-13H,4-7,9H2,1-3H3,(H,24,27)(H,26,28)/t11-,19?/m0/s1
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n/an/an/an/a 33.2n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240533
PNG
(US9409866, 248 | US9409866, 258 | US9409866, 259)
Show SMILES C[C@H](Oc1cc(ncc1C1CC1)C(=O)NC(C)(CC(N)=O)C1CC1)C(F)(F)F |r|
Show InChI InChI=1S/C19H24F3N3O3/c1-10(19(20,21)22)28-15-7-14(24-9-13(15)11-3-4-11)17(27)25-18(2,8-16(23)26)12-5-6-12/h7,9-12H,3-6,8H2,1-2H3,(H2,23,26)(H,25,27)/t10-,18?/m0/s1
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n/an/an/an/a 13n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240553
PNG
(US9409866, 268 | US9409866, 269)
Show SMILES CC1(COC1)C(NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1)C(N)=O
Show InChI InChI=1S/C17H20F3N3O4/c1-16(6-26-7-16)13(14(21)24)23-15(25)11-4-12(27-8-17(18,19)20)10(5-22-11)9-2-3-9/h4-5,9,13H,2-3,6-8H2,1H3,(H2,21,24)(H,23,25)
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n/an/an/an/a 771n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240567
PNG
(US9409866, 282)
Show SMILES CNC(=O)CC1(CS(=O)(=O)C1)NC(=O)c1cc(OCC(F)(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C17H20F3N3O5S/c1-21-14(24)5-16(8-29(26,27)9-16)23-15(25)12-4-13(28-7-17(18,19)20)11(6-22-12)10-2-3-10/h4,6,10H,2-3,5,7-9H2,1H3,(H,21,24)(H,23,25)
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n/an/an/an/a 659n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240568
PNG
(US9409866, 283 | US9409866, 284)
Show SMILES Cc1nc(no1)C(C)(CS(C)(=O)=O)NC(=O)c1cc(OCC(F)F)c(cn1)C1CC1
Show InChI InChI=1S/C18H22F2N4O5S/c1-10-22-17(24-29-10)18(2,9-30(3,26)27)23-16(25)13-6-14(28-8-15(19)20)12(7-21-13)11-4-5-11/h6-7,11,15H,4-5,8-9H2,1-3H3,(H,23,25)
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n/an/an/an/a 53.3n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM240576
PNG
(US9409866, 291 | US9409866, 292)
Show SMILES CC(CF)Oc1cc(ncc1C1CC1)C(=O)NC1(CC(N)=O)CS(=O)(=O)C1
Show InChI InChI=1S/C17H22FN3O5S/c1-10(6-18)26-14-4-13(20-7-12(14)11-2-3-11)16(23)21-17(5-15(19)22)8-27(24,25)9-17/h4,7,10-11H,2-3,5-6,8-9H2,1H3,(H2,19,22)(H,21,23)
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n/an/an/an/a 0.300n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM240290
PNG
(US9409866, 5)
Show SMILES OC1(CNC(=O)c2cc(OCC3CC3)c(Cl)cn2)CCCCC1
Show InChI InChI=1S/C17H23ClN2O3/c18-13-9-19-14(8-15(13)23-10-12-4-5-12)16(21)20-11-17(22)6-2-1-3-7-17/h8-9,12,22H,1-7,10-11H2,(H,20,21)
PDB

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n/an/an/an/a>1.00E+4n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM240292
PNG
(US9409866, 7)
Show SMILES CC(C)C[C@@H](CO)NC(=O)c1cc(OCC2CC2)c(Cl)cn1 |r|
Show InChI InChI=1S/C16H23ClN2O3/c1-10(2)5-12(8-20)19-16(21)14-6-15(13(17)7-18-14)22-9-11-3-4-11/h6-7,10-12,20H,3-5,8-9H2,1-2H3,(H,19,21)/t12-/m0/s1
PDB

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n/an/an/an/a>1.00E+4n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM240293
PNG
(US9409866, 8)
Show SMILES CC(C)(NC(=O)c1cc(OCC2CC2)c(Cl)cn1)C#N
Show InChI InChI=1S/C14H16ClN3O2/c1-14(2,8-16)18-13(19)11-5-12(10(15)6-17-11)20-7-9-3-4-9/h5-6,9H,3-4,7H2,1-2H3,(H,18,19)
PDB

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n/an/an/an/a>1.00E+4n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...

US Patent US9409866 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78BD
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%