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Patent code US9422243

Compile Data Set for Download or QSAR
Found 55 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240715
PNG
(US9422243, 13)
Show SMILES Cc1cc(ccc1Cl)-c1[nH]c(=O)c2cc(F)ccc2c1OCCN
Show InChI InChI=1S/C18H16ClFN2O2/c1-10-8-11(2-5-15(10)19)16-17(24-7-6-21)13-4-3-12(20)9-14(13)18(23)22-16/h2-5,8-9H,6-7,21H2,1H3,(H,22,23)
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US Patent
n/an/a 0.200n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240716
PNG
(US9422243, 14)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H13Cl2FN2O2/c18-13-4-1-9(7-14(13)19)15-16(24-6-5-21)11-3-2-10(20)8-12(11)17(23)22-15/h1-4,7-8H,5-6,21H2,(H,22,23)
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US Patent
n/an/a 1n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240721
PNG
(US9422243, 21)
Show SMILES COc1ccc(cc1F)-c1[nH]c(=O)c2cc(F)ccc2c1OCCN
Show InChI InChI=1S/C18H16F2N2O3/c1-24-15-5-2-10(8-14(15)20)16-17(25-7-6-21)12-4-3-11(19)9-13(12)18(23)22-16/h2-5,8-9H,6-7,21H2,1H3,(H,22,23)
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US Patent
n/an/a 6n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240711
PNG
(US9422243, 8)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H14ClFN2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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US Patent
n/an/a 10n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240713
PNG
(US9422243, 11)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(c1)C#N
Show InChI InChI=1S/C18H14FN3O2/c19-13-4-5-14-15(9-13)18(23)22-16(17(14)24-7-6-20)12-3-1-2-11(8-12)10-21/h1-5,8-9H,6-7,20H2,(H,22,23)
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US Patent
n/an/a 10n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240704
PNG
(US9422243, 1)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C17H14BrFN2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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n/an/a 10n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240707
PNG
(US9422243, 4)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCOCC2)c(Br)c1
Show InChI InChI=1S/C21H21BrFN3O3/c22-17-11-13(1-4-18(17)26-6-9-28-10-7-26)19-20(29-8-5-24)15-3-2-14(23)12-16(15)21(27)25-19/h1-4,11-12H,5-10,24H2,(H,25,27)
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n/an/a 20n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240714
PNG
(US9422243, 12)
Show SMILES NCCOc1c([nH]c(=O)c2c(F)c(F)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C17H13BrF2N2O2/c18-10-3-1-9(2-4-10)15-16(24-8-7-21)11-5-6-12(19)14(20)13(11)17(23)22-15/h1-6H,7-8,21H2,(H,22,23)
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n/an/a 20n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240705
PNG
(US9422243, 2)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H14F4N2O2/c19-12-4-5-13-14(9-12)17(25)24-15(16(13)26-7-6-23)10-2-1-3-11(8-10)18(20,21)22/h1-5,8-9H,6-7,23H2,(H,24,25)
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n/an/a 30n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240712
PNG
(US9422243, 10)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C17H14F2N2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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US Patent
n/an/a 60n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240719
PNG
(US9422243, 19)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc2OCCOc2c1
Show InChI InChI=1S/C19H17FN2O4/c20-12-2-3-13-14(10-12)19(23)22-17(18(13)26-6-5-21)11-1-4-15-16(9-11)25-8-7-24-15/h1-4,9-10H,5-8,21H2,(H,22,23)
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US Patent
n/an/a 70n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240720
PNG
(US9422243, 20)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C18H15FN2O4/c19-11-2-3-12-13(8-11)18(22)21-16(17(12)23-6-5-20)10-1-4-14-15(7-10)25-9-24-14/h1-4,7-8H,5-6,9,20H2,(H,21,22)
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n/an/a 80n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240708
PNG
(US9422243, 5)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(Br)c1
Show InChI InChI=1S/C17H14BrFN2O2/c18-11-3-1-2-10(8-11)15-16(23-7-6-20)13-5-4-12(19)9-14(13)17(22)21-15/h1-5,8-9H,6-7,20H2,(H,21,22)
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n/an/a 100n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240717
PNG
(US9422243, 15)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(F)c(F)c1
Show InChI InChI=1S/C17H13F3N2O2/c18-10-2-3-11-12(8-10)17(23)22-15(16(11)24-6-5-21)9-1-4-13(19)14(20)7-9/h1-4,7-8H,5-6,21H2,(H,22,23)
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n/an/a 130n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240718
PNG
(US9422243, 18)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCCC2)c(Br)c1
Show InChI InChI=1S/C21H21BrFN3O2/c22-17-11-13(3-6-18(17)26-8-1-2-9-26)19-20(28-10-7-24)15-5-4-14(23)12-16(15)21(27)25-19/h3-6,11-12H,1-2,7-10,24H2,(H,25,27)
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n/an/a 130n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240710
PNG
(US9422243, 7)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H22FN3O2/c22-15-5-8-17-18(13-15)21(26)24-19(20(17)27-12-9-23)14-3-6-16(7-4-14)25-10-1-2-11-25/h3-8,13H,1-2,9-12,23H2,(H,24,26)
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n/an/a 210n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240722
PNG
(US9422243, Ref. compound A)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C23H19FN2O3/c24-16-8-11-19-20(14-16)23(27)26-21(22(19)28-13-12-25)15-6-9-18(10-7-15)29-17-4-2-1-3-5-17/h1-11,14H,12-13,25H2,(H,26,27)
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n/an/a 230n/an/an/an/an/a37



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 2


(Homo sapiens (Human))
BDBM240710
PNG
(US9422243, 7)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H22FN3O2/c22-15-5-8-17-18(13-15)21(26)24-19(20(17)27-12-9-23)14-3-6-16(7-4-14)25-10-1-2-11-25/h3-8,13H,1-2,9-12,23H2,(H,24,26)
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n/an/an/a 1.19E+3n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240707
PNG
(US9422243, 4)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCOCC2)c(Br)c1
Show InChI InChI=1S/C21H21BrFN3O3/c22-17-11-13(1-4-18(17)26-6-9-28-10-7-26)19-20(29-8-5-24)15-3-2-14(23)12-16(15)21(27)25-19/h1-4,11-12H,5-10,24H2,(H,25,27)
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n/an/an/a 90n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240715
PNG
(US9422243, 13)
Show SMILES Cc1cc(ccc1Cl)-c1[nH]c(=O)c2cc(F)ccc2c1OCCN
Show InChI InChI=1S/C18H16ClFN2O2/c1-10-8-11(2-5-15(10)19)16-17(24-7-6-21)13-4-3-12(20)9-14(13)18(23)22-16/h2-5,8-9H,6-7,21H2,1H3,(H,22,23)
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n/an/an/a 34n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240717
PNG
(US9422243, 15)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(F)c(F)c1
Show InChI InChI=1S/C17H13F3N2O2/c18-10-2-3-11-12(8-10)17(23)22-15(16(11)24-6-5-21)9-1-4-13(19)14(20)7-9/h1-4,7-8H,5-6,21H2,(H,22,23)
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n/an/an/a 20n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240718
PNG
(US9422243, 18)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCCC2)c(Br)c1
Show InChI InChI=1S/C21H21BrFN3O2/c22-17-11-13(3-6-18(17)26-8-1-2-9-26)19-20(28-10-7-24)15-5-4-14(23)12-16(15)21(27)25-19/h3-6,11-12H,1-2,7-10,24H2,(H,25,27)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240709
PNG
(US9422243, 6)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C18H14FN3O2/c19-13-5-6-14-15(9-13)18(23)22-16(17(14)24-8-7-20)12-3-1-11(10-21)2-4-12/h1-6,9H,7-8,20H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240711
PNG
(US9422243, 8)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H14ClFN2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240713
PNG
(US9422243, 11)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(c1)C#N
Show InChI InChI=1S/C18H14FN3O2/c19-13-4-5-14-15(9-13)18(23)22-16(17(14)24-7-6-20)12-3-1-2-11(8-12)10-21/h1-5,8-9H,6-7,20H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240715
PNG
(US9422243, 13)
Show SMILES Cc1cc(ccc1Cl)-c1[nH]c(=O)c2cc(F)ccc2c1OCCN
Show InChI InChI=1S/C18H16ClFN2O2/c1-10-8-11(2-5-15(10)19)16-17(24-7-6-21)13-4-3-12(20)9-14(13)18(23)22-16/h2-5,8-9H,6-7,21H2,1H3,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240720
PNG
(US9422243, 20)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C18H15FN2O4/c19-11-2-3-12-13(8-11)18(22)21-16(17(12)23-6-5-20)10-1-4-14-15(7-10)25-9-24-14/h1-4,7-8H,5-6,9,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 2


(Homo sapiens (Human))
BDBM240706
PNG
(US9422243, 3)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C21H22FN3O3/c22-15-3-6-17-18(13-15)21(26)24-19(20(17)28-10-7-23)14-1-4-16(5-2-14)25-8-11-27-12-9-25/h1-6,13H,7-12,23H2,(H,24,26)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 2


(Homo sapiens (Human))
BDBM240707
PNG
(US9422243, 4)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCOCC2)c(Br)c1
Show InChI InChI=1S/C21H21BrFN3O3/c22-17-11-13(1-4-18(17)26-6-9-28-10-7-26)19-20(29-8-5-24)15-3-2-14(23)12-16(15)21(27)25-19/h1-4,11-12H,5-10,24H2,(H,25,27)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240705
PNG
(US9422243, 2)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H14F4N2O2/c19-12-4-5-13-14(9-12)17(25)24-15(16(13)26-7-6-23)10-2-1-3-11(8-10)18(20,21)22/h1-5,8-9H,6-7,23H2,(H,24,25)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240711
PNG
(US9422243, 8)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H14ClFN2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240714
PNG
(US9422243, 12)
Show SMILES NCCOc1c([nH]c(=O)c2c(F)c(F)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C17H13BrF2N2O2/c18-10-3-1-9(2-4-10)15-16(24-8-7-21)11-5-6-12(19)14(20)13(11)17(23)22-15/h1-6H,7-8,21H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240710
PNG
(US9422243, 7)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H22FN3O2/c22-15-5-8-17-18(13-15)21(26)24-19(20(17)27-12-9-23)14-3-6-16(7-4-14)25-10-1-2-11-25/h3-8,13H,1-2,9-12,23H2,(H,24,26)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240712
PNG
(US9422243, 10)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C17H14F2N2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 2


(Homo sapiens (Human))
BDBM240704
PNG
(US9422243, 1)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C17H14BrFN2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 2


(Homo sapiens (Human))
BDBM240709
PNG
(US9422243, 6)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C18H14FN3O2/c19-13-5-6-14-15(9-13)18(23)22-16(17(14)24-8-7-20)12-3-1-11(10-21)2-4-12/h1-6,9H,7-8,20H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240713
PNG
(US9422243, 11)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(c1)C#N
Show InChI InChI=1S/C18H14FN3O2/c19-13-4-5-14-15(9-13)18(23)22-16(17(14)24-7-6-20)12-3-1-2-11(8-12)10-21/h1-5,8-9H,6-7,20H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240719
PNG
(US9422243, 19)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc2OCCOc2c1
Show InChI InChI=1S/C19H17FN2O4/c20-12-2-3-13-14(10-12)19(23)22-17(18(13)26-6-5-21)11-1-4-15-16(9-11)25-8-7-24-15/h1-4,9-10H,5-8,21H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240718
PNG
(US9422243, 18)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCCC2)c(Br)c1
Show InChI InChI=1S/C21H21BrFN3O2/c22-17-11-13(3-6-18(17)26-8-1-2-9-26)19-20(28-10-7-24)15-5-4-14(23)12-16(15)21(27)25-19/h3-6,11-12H,1-2,7-10,24H2,(H,25,27)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240716
PNG
(US9422243, 14)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H13Cl2FN2O2/c18-13-4-1-9(7-14(13)19)15-16(24-6-5-21)11-3-2-10(20)8-12(11)17(23)22-15/h1-4,7-8H,5-6,21H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240707
PNG
(US9422243, 4)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCOCC2)c(Br)c1
Show InChI InChI=1S/C21H21BrFN3O3/c22-17-11-13(1-4-18(17)26-6-9-28-10-7-26)19-20(29-8-5-24)15-3-2-14(23)12-16(15)21(27)25-19/h1-4,11-12H,5-10,24H2,(H,25,27)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240721
PNG
(US9422243, 21)
Show SMILES COc1ccc(cc1F)-c1[nH]c(=O)c2cc(F)ccc2c1OCCN
Show InChI InChI=1S/C18H16F2N2O3/c1-24-15-5-2-10(8-14(15)20)16-17(25-7-6-21)12-4-3-11(19)9-13(12)18(23)22-16/h2-5,8-9H,6-7,21H2,1H3,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240716
PNG
(US9422243, 14)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H13Cl2FN2O2/c18-13-4-1-9(7-14(13)19)15-16(24-6-5-21)11-3-2-10(20)8-12(11)17(23)22-15/h1-4,7-8H,5-6,21H2,(H,22,23)
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n/an/an/a 10n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 2


(Homo sapiens (Human))
BDBM240705
PNG
(US9422243, 2)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H14F4N2O2/c19-12-4-5-13-14(9-12)17(25)24-15(16(13)26-7-6-23)10-2-1-3-11(8-10)18(20,21)22/h1-5,8-9H,6-7,23H2,(H,24,25)
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n/an/an/a 1.96E+3n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240704
PNG
(US9422243, 1)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C17H14BrFN2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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n/an/an/a<10n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240720
PNG
(US9422243, 20)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C18H15FN2O4/c19-11-2-3-12-13(8-11)18(22)21-16(17(12)23-6-5-20)10-1-4-14-15(7-10)25-9-24-14/h1-4,7-8H,5-6,9,20H2,(H,21,22)
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n/an/an/a<10n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240719
PNG
(US9422243, 19)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc2OCCOc2c1
Show InChI InChI=1S/C19H17FN2O4/c20-12-2-3-13-14(10-12)19(23)22-17(18(13)26-6-5-21)11-1-4-15-16(9-11)25-8-7-24-15/h1-4,9-10H,5-8,21H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240712
PNG
(US9422243, 10)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C17H14F2N2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240717
PNG
(US9422243, 15)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(F)c(F)c1
Show InChI InChI=1S/C17H13F3N2O2/c18-10-2-3-11-12(8-10)17(23)22-15(16(11)24-6-5-21)9-1-4-13(19)14(20)7-9/h1-4,7-8H,5-6,21H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240714
PNG
(US9422243, 12)
Show SMILES NCCOc1c([nH]c(=O)c2c(F)c(F)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C17H13BrF2N2O2/c18-10-3-1-9(2-4-10)15-16(24-8-7-21)11-5-6-12(19)14(20)13(11)17(23)22-15/h1-6H,7-8,21H2,(H,22,23)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240706
PNG
(US9422243, 3)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C21H22FN3O3/c22-15-3-6-17-18(13-15)21(26)24-19(20(17)28-10-7-23)14-1-4-16(5-2-14)25-8-11-27-12-9-25/h1-6,13H,7-12,23H2,(H,24,26)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H]


(Homo sapiens (Human))
BDBM240704
PNG
(US9422243, 1)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C17H14BrFN2O2/c18-11-3-1-10(2-4-11)15-16(23-8-7-20)13-6-5-12(19)9-14(13)17(22)21-15/h1-6,9H,7-8,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 2


(Homo sapiens (Human))
BDBM240708
PNG
(US9422243, 5)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(Br)c1
Show InChI InChI=1S/C17H14BrFN2O2/c18-11-3-1-2-10(8-11)15-16(23-7-6-20)13-5-4-12(19)9-14(13)17(22)21-15/h1-5,8-9H,6-7,20H2,(H,21,22)
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n/an/an/a 1.00E+3n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240708
PNG
(US9422243, 5)
Show SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1cccc(Br)c1
Show InChI InChI=1S/C17H14BrFN2O2/c18-11-3-1-2-10(8-11)15-16(23-7-6-20)13-5-4-12(19)9-14(13)17(22)21-15/h1-5,8-9H,6-7,20H2,(H,21,22)
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NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM240721
PNG
(US9422243, 21)
Show SMILES COc1ccc(cc1F)-c1[nH]c(=O)c2cc(F)ccc2c1OCCN
Show InChI InChI=1S/C18H16F2N2O3/c1-24-15-5-2-10(8-14(15)20)16-17(25-7-6-21)12-4-3-11(19)9-13(12)18(23)22-16/h2-5,8-9H,6-7,21H2,1H3,(H,22,23)
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n/an/an/a<10n/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L. a corporation

US Patent


Assay Description
The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...


US Patent US9422243 (2016)


BindingDB Entry DOI: 10.7270/Q2T72GBH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%