Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431246 (CHEMBL2333062 | US9428465, 32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431271 (CHEMBL2333033 | US9428465, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Homo sapiens (Human)) | BDBM241946 (US9428465, 24) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Homo sapiens (Human)) | BDBM50431262 (CHEMBL2333042 | US9428465, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM241944 (US9428465, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431262 (CHEMBL2333042 | US9428465, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 51 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431272 (CHEMBL2333032 | US9428465, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 67 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431263 (CHEMBL2333041 | US9428465, 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 147 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Homo sapiens (Human)) | BDBM50431264 (CHEMBL2333040 | US9428465, 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | US Patent | n/a | n/a | 155 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431264 (CHEMBL2333040 | US9428465, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | US Patent | n/a | n/a | 177 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Homo sapiens (Human)) | BDBM241945 (US9428465, 23) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 270 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431269 (CHEMBL2333035 | US9428465, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 420 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431266 (CHEMBL2333038 | US9428465, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 880 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431268 (CHEMBL2333036 | US9428465, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431265 (CHEMBL2333039 | US9428465, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431261 (CHEMBL2333044 | US9428465, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Rattus norvegicus (Rat)) | BDBM50431267 (CHEMBL2333037 | US9428465, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Fondazione Istituto Italiano Di Technologia US Patent | Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1... | US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB | |||||||||||
More data for this Ligand-Target Pair |