Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM241947 (US9428466, 4'-hydroxymerbarone) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM241948 (US9428466, 4'-hydroxy-2-oxo-desthiomerbarone) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM46100 (6-hydroxy-2,4-diketo-N-phenyl-1H-pyrimidine-5-carb...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM50016784 (ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Similars | DrugBank US Patent | n/a | n/a | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM241948 (US9428466, 4'-hydroxy-2-oxo-desthiomerbarone) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM241949 (US9428466, Merbarone) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM241947 (US9428466, 4'-hydroxymerbarone) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM241949 (US9428466, Merbarone) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 2.74E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM46100 (6-hydroxy-2,4-diketo-N-phenyl-1H-pyrimidine-5-carb...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:... | US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
