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Patent code US9447106

Compile Data Set for Download or QSAR

Found 218 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250014
PNG
(US10005782, Compound 136 | US9447106, 136 | US9556...)
Show SMILES NC(=O)c1c(nn2c(c[nH]c12)C1CCN(CC1)C(=O)C=C)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C26H25N5O3/c1-2-22(32)30-14-12-17(13-15-30)21-16-28-26-23(25(27)33)24(29-31(21)26)18-8-10-20(11-9-18)34-19-6-4-3-5-7-19/h2-11,16-17,28H,1,12-15H2,(H2,27,33)
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n/an/a 0.130n/an/an/an/an/a25



BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249925
PNG
(US10005782, Compound 52 | US9447106, 52 | US955618...)
Show SMILES NC(=O)c1c(nn2c3CN(CCc3[nH]c12)C(=O)C=C)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C24H21N5O3/c1-2-20(30)28-13-12-18-19(14-28)29-24(26-18)21(23(25)31)22(27-29)15-8-10-17(11-9-15)32-16-6-4-3-5-7-16/h2-11,26H,1,12-14H2,(H2,25,31)
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n/an/a 0.140n/an/an/an/an/a25



BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250047
PNG
(US10005782, Compound 169 | US9447106, 169 | US9556...)
Show SMILES COc1c(Cl)cc(cc1Cl)-c1nn2C(CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C
Show InChI InChI=1S/C23H21Cl2N5O3/c1-3-18(31)28-16-7-5-4-6-13(16)17-8-9-27-23-19(22(26)32)20(29-30(17)23)12-10-14(24)21(33-2)15(25)11-12/h3-7,10-11,17,27H,1,8-9H2,2H3,(H2,26,32)(H,28,31)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249997
PNG
(US10005782, Compound 123 | US9447106, 123 | US9556...)
Show SMILES NC(=O)c1c(nn2c3CN(CCCc3[nH]c12)C(=O)C=C)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C25H23N5O3/c1-2-21(31)29-14-6-9-19-20(15-29)30-25(27-19)22(24(26)32)23(28-30)16-10-12-18(13-11-16)33-17-7-4-3-5-8-17/h2-5,7-8,10-13,27H,1,6,9,14-15H2,(H2,26,32)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249935
PNG
(US10005782, Compound 64 | US9447106, 64 | US955618...)
Show SMILES CN(C)C\C=C\C(=O)N1CCc2c(C1)[nH]c1c(C(N)=O)c(nn21)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C27H28N6O3/c1-31(2)15-6-9-23(34)32-16-14-22-21(17-32)29-27-24(26(28)35)25(30-33(22)27)18-10-12-20(13-11-18)36-19-7-4-3-5-8-19/h3-13,29H,14-17H2,1-2H3,(H2,28,35)/b9-6+
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249934
PNG
(US10005782, Compound 63 | US9447106, 63 | US955618...)
Show SMILES NC(=O)c1c(nn2c3CCN(Cc3[nH]c12)C(=O)C=C)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C24H21N5O3/c1-2-20(30)28-13-12-19-18(14-28)26-24-21(23(25)31)22(27-29(19)24)15-8-10-17(11-9-15)32-16-6-4-3-5-7-16/h2-11,26H,1,12-14H2,(H2,25,31)
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n/an/a 0.180n/an/an/an/an/a25



BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249927
PNG
(US10005782, Compound 54 | US9447106, 54 | US955618...)
Show SMILES CN(C)C\C=C\C(=O)N1CCc2[nH]c3c(C(N)=O)c(nn3c2C1)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C27H28N6O3/c1-31(2)15-6-9-23(34)32-16-14-21-22(17-32)33-27(29-21)24(26(28)35)25(30-33)18-10-12-20(13-11-18)36-19-7-4-3-5-8-19/h3-13,29H,14-17H2,1-2H3,(H2,28,35)/b9-6+
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n/an/a 0.190n/an/an/an/an/a25



BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250008
PNG
(US9447106, 133a (peak 1))
Show SMILES COc1cc(ccc1C)-c1nn2[C@H](CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C |r|
Show InChI InChI=1S/C24H25N5O3/c1-4-20(30)27-17-8-6-5-7-16(17)18-11-12-26-24-21(23(25)31)22(28-29(18)24)15-10-9-14(2)19(13-15)32-3/h4-10,13,18,26H,1,11-12H2,2-3H3,(H2,25,31)(H,27,30)/t18-/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249938
PNG
(US10005782, Compound 67 | US9447106, 67 | US955618...)
Show SMILES NC(=O)c1c(nn2c3cc(NC(=O)C=C)ccc3[nH]c12)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C25H19N5O3/c1-2-21(31)27-16-10-13-19-20(14-16)30-25(28-19)22(24(26)32)23(29-30)15-8-11-18(12-9-15)33-17-6-4-3-5-7-17/h2-14,28H,1H2,(H2,26,32)(H,27,31)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250081
PNG
(US9447106, 27a (peak 1) | US9556188, Compound 27b)
Show SMILES NC(=O)c1c2NCC[C@H](C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m1/s1
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n/an/a 0.330n/an/an/an/an/a25



BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249995
PNG
(US10005782, Compound 121 | US9447106, 121 | US9556...)
Show SMILES NC(=O)c1c(nn2c3CCN(CCc3[nH]c12)C(=O)C=C)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C25H23N5O3/c1-2-21(31)29-14-12-19-20(13-15-29)30-25(27-19)22(24(26)32)23(28-30)16-8-10-18(11-9-16)33-17-6-4-3-5-7-17/h2-11,27H,1,12-15H2,(H2,26,32)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250035
PNG
(US10005782, Compound 157 | US9447106, 157 | US9556...)
Show SMILES Cc1cc(ccc1F)-c1nn2C(CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C
Show InChI InChI=1S/C23H22FN5O2/c1-3-19(30)27-17-7-5-4-6-15(17)18-10-11-26-23-20(22(25)31)21(28-29(18)23)14-8-9-16(24)13(2)12-14/h3-9,12,18,26H,1,10-11H2,2H3,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250013
PNG
(US10005782, Compound 135 | US9447106, 135 | US9556...)
Show SMILES NC(=O)c1c2NCCC(C3CN(C3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2C#N)cc1
Show InChI InChI=1S/C26H24N6O3/c1-2-22(33)31-14-18(15-31)20-11-12-29-26-23(25(28)34)24(30-32(20)26)16-7-9-19(10-8-16)35-21-6-4-3-5-17(21)13-27/h2-10,18,20,29H,1,11-12,14-15H2,(H2,28,34)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250075
PNG
(US9447106, 6a (peak 1) | US9556188, Compound 6b)
Show SMILES NC(=O)c1c2NCC[C@H](c3ccccc3NC(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C28H25N5O3/c1-2-24(34)31-22-11-7-6-10-21(22)23-16-17-30-28-25(27(29)35)26(32-33(23)28)18-12-14-20(15-13-18)36-19-8-4-3-5-9-19/h2-15,23,30H,1,16-17H2,(H2,29,35)(H,31,34)/t23-/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250083
PNG
(US9447106, 29a (peak 1) | US9556188, Compound 29b)
Show SMILES NC(=O)c1c2NCC[C@H](C3CN(C3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C25H25N5O3/c1-2-21(31)29-14-17(15-29)20-12-13-27-25-22(24(26)32)23(28-30(20)25)16-8-10-19(11-9-16)33-18-6-4-3-5-7-18/h2-11,17,20,27H,1,12-15H2,(H2,26,32)/t20-/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249930
PNG
(US10005782, Compound 58 | US9447106, 58 | US955618...)
Show SMILES CC=CC(=O)N1CCc2[nH]c3c(C(N)=O)c(nn3c2C1)-c1ccc(Oc2ccccc2)cc1 |w:1.0|
Show InChI InChI=1S/C25H23N5O3/c1-2-6-21(31)29-14-13-19-20(15-29)30-25(27-19)22(24(26)32)23(28-30)16-9-11-18(12-10-16)33-17-7-4-3-5-8-17/h2-12,27H,13-15H2,1H3,(H2,26,32)/b6-2+
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250017
PNG
(US10005782, Compound 139 | US9447106, 139 | US9556...)
Show SMILES NC(=O)c1c2NCCC(C3CN(C3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C25H24ClN5O3/c1-2-21(32)30-13-16(14-30)19-10-11-28-25-22(24(27)33)23(29-31(19)25)15-8-9-20(18(26)12-15)34-17-6-4-3-5-7-17/h2-9,12,16,19,28H,1,10-11,13-14H2,(H2,27,33)
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n/an/a 0.440n/an/an/an/an/a25



BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249902
PNG
(US10005782, Compound 29b | US9447106, 119 | US9447...)
Show SMILES NC(=O)c1c2NCCC(C3CN(C3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C25H25N5O3/c1-2-21(31)29-14-17(15-29)20-12-13-27-25-22(24(26)32)23(28-30(20)25)16-8-10-19(11-9-16)33-18-6-4-3-5-7-18/h2-11,17,20,27H,1,12-15H2,(H2,26,32)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249981
PNG
(US10005782, Compound 107 | US9447106, 107 | US9556...)
Show SMILES NC(=O)c1c2NCCC(C3CN(C3)C(=O)C=C)n2nc1-c1ccc(Oc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C25H24ClN5O3/c1-2-21(32)30-13-16(14-30)20-10-11-28-25-22(24(27)33)23(29-31(20)25)15-6-8-18(9-7-15)34-19-5-3-4-17(26)12-19/h2-9,12,16,20,28H,1,10-11,13-14H2,(H2,27,33)
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n/an/a 0.480n/an/an/an/an/a25



BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250038
PNG
(US10005782, Compound 160 | US9447106, 160 | US9556...)
Show SMILES COc1cc(ccc1Cl)-c1nn2C(CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C
Show InChI InChI=1S/C23H22ClN5O3/c1-3-19(30)27-16-7-5-4-6-14(16)17-10-11-26-23-20(22(25)31)21(28-29(17)23)13-8-9-15(24)18(12-13)32-2/h3-9,12,17,26H,1,10-11H2,2H3,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250077
PNG
(US9447106, 10a (peak 1) | US9556188, Compound 10b)
Show SMILES NC(=O)c1c2NCC[C@H](c3ccccc3NC(=O)C=C)n2nc1-c1ccc(OCc2ccccc2)cc1 |r|
Show InChI InChI=1S/C29H27N5O3/c1-2-25(35)32-23-11-7-6-10-22(23)24-16-17-31-29-26(28(30)36)27(33-34(24)29)20-12-14-21(15-13-20)37-18-19-8-4-3-5-9-19/h2-15,24,31H,1,16-18H2,(H2,30,36)(H,32,35)/t24-/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250007
PNG
(US10005782, Compound 133b | US9447106, 133 | US955...)
Show SMILES COc1cc(ccc1C)-c1nn2C(CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C
Show InChI InChI=1S/C24H25N5O3/c1-4-20(30)27-17-8-6-5-7-16(17)18-11-12-26-24-21(23(25)31)22(28-29(18)24)15-10-9-14(2)19(13-15)32-3/h4-10,13,18,26H,1,11-12H2,2-3H3,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250034
PNG
(US10005782, Compound 156 | US9447106, 156 | US9556...)
Show SMILES NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H19Cl2N5O2/c1-2-18(30)27-16-6-4-3-5-13(16)17-9-10-26-22-19(21(25)31)20(28-29(17)22)12-7-8-14(23)15(24)11-12/h2-8,11,17,26H,1,9-10H2,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250087
PNG
(US9447106, 33a (peak 1) | US9556188, Compound 33b)
Show SMILES NC(=O)c1c2NCC[C@H](CNC(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C23H23N5O3/c1-2-19(29)26-14-16-12-13-25-23-20(22(24)30)21(27-28(16)23)15-8-10-18(11-9-15)31-17-6-4-3-5-7-17/h2-11,16,25H,1,12-14H2,(H2,24,30)(H,26,29)/t16-/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249998
PNG
(US10005782, Compound 124 | US9447106, 124 | US9556...)
Show SMILES CN(C)C\C=C\C(=O)N1CCCc2[nH]c3c(C(N)=O)c(nn3c2C1)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C28H30N6O3/c1-32(2)16-7-11-24(35)33-17-6-10-22-23(18-33)34-28(30-22)25(27(29)36)26(31-34)19-12-14-21(15-13-19)37-20-8-4-3-5-9-20/h3-5,7-9,11-15,30H,6,10,16-18H2,1-2H3,(H2,29,36)/b11-7+
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250011
PNG
(US9447106, 134a (peak 1))
Show SMILES NC(=O)c1c2NCC[C@H](c3ccccc3NC(=O)C=C)n2nc1-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C22H20ClN5O2/c1-2-18(29)26-16-6-4-3-5-15(16)17-11-12-25-22-19(21(24)30)20(27-28(17)22)13-7-9-14(23)10-8-13/h2-10,17,25H,1,11-12H2,(H2,24,30)(H,26,29)/t17-/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250085
PNG
(US10005782, Compound 30a | US9447106, 30a (peak 1))
Show SMILES NC(=O)c1c2NC[C@@H]3CN(CC[C@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C |r|
Show InChI InChI=1S/C25H25N5O3/c1-2-21(31)29-13-12-20-17(15-29)14-27-25-22(24(26)32)23(28-30(20)25)16-8-10-19(11-9-16)33-18-6-4-3-5-7-18/h2-11,17,20,27H,1,12-15H2,(H2,26,32)/t17-,20-/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250066
PNG
(US10005782, Compound 191 | US9447106, 191 | US9556...)
Show SMILES NC(=O)c1c2NCC[C@@H](C3CCN(CC3)C(=O)C#CCO)n2nc1-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C28H29N5O4/c29-27(36)25-26(20-8-10-22(11-9-20)37-21-5-2-1-3-6-21)31-33-23(12-15-30-28(25)33)19-13-16-32(17-14-19)24(35)7-4-18-34/h1-3,5-6,8-11,19,23,30,34H,12-18H2,(H2,29,36)/t23-/m0/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249879
PNG
(US10005782, Compound 6b | US9447106, 6 | US9556188...)
Show SMILES NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C28H25N5O3/c1-2-24(34)31-22-11-7-6-10-21(22)23-16-17-30-28-25(27(29)35)26(32-33(23)28)18-12-14-20(15-13-18)36-19-8-4-3-5-9-19/h2-15,23,30H,1,16-17H2,(H2,29,35)(H,31,34)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250010
PNG
(US10005782, Compound 134b | US9447106, 134 | US955...)
Show SMILES NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H20ClN5O2/c1-2-18(29)26-16-6-4-3-5-15(16)17-11-12-25-22-19(21(24)30)20(27-28(17)22)13-7-9-14(23)10-8-13/h2-10,17,25H,1,11-12H2,(H2,24,30)(H,26,29)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249996
PNG
(US10005782, Compound 122 | US9447106, 122 | US9556...)
Show SMILES CN(C)C\C=C\C(=O)N1CCc2[nH]c3c(C(N)=O)c(nn3c2CC1)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C28H30N6O3/c1-32(2)16-6-9-24(35)33-17-14-22-23(15-18-33)34-28(30-22)25(27(29)36)26(31-34)19-10-12-21(13-11-19)37-20-7-4-3-5-8-20/h3-13,30H,14-18H2,1-2H3,(H2,29,36)/b9-6+
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250051
PNG
(US10005782, Compound 173 | US9447106, 173 | US9556...)
Show SMILES NC(=O)c1c2NCCC(C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C27H28ClN5O3/c1-2-23(34)32-14-11-17(12-15-32)21-10-13-30-27-24(26(29)35)25(31-33(21)27)18-8-9-22(20(28)16-18)36-19-6-4-3-5-7-19/h2-9,16-17,21,30H,1,10-15H2,(H2,29,35)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250021
PNG
(US10005782, Compound 143 | US9447106, 143 | US9556...)
Show SMILES CC1(CNC(=O)C=C)CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C24H25N5O3/c1-3-19(30)27-15-24(2)13-14-26-23-20(22(25)31)21(28-29(23)24)16-9-11-18(12-10-16)32-17-7-5-4-6-8-17/h3-12,26H,1,13-15H2,2H3,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249906
PNG
(US10005782, Compound 33b | US9447106, 33 | US95561...)
Show SMILES NC(=O)c1c2NCCC(CNC(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C23H23N5O3/c1-2-19(29)26-14-16-12-13-25-23-20(22(24)30)21(27-28(16)23)15-8-10-18(11-9-15)31-17-6-4-3-5-7-17/h2-11,16,25H,1,12-14H2,(H2,24,30)(H,26,29)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250067
PNG
(US10005782, Compound 192 | US9447106, 192 | US9556...)
Show SMILES COCC#CC(=O)N1CCC(CC1)[C@@H]1CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C29H31N5O4/c1-37-19-5-8-25(35)33-17-14-20(15-18-33)24-13-16-31-29-26(28(30)36)27(32-34(24)29)21-9-11-23(12-10-21)38-22-6-3-2-4-7-22/h2-4,6-7,9-12,20,24,31H,13-19H2,1H3,(H2,30,36)/t24-/m0/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250033
PNG
(US10005782, Compound 155 | US9447106, 155 | US9556...)
Show SMILES NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1cccc(Cl)c1
Show InChI InChI=1S/C22H20ClN5O2/c1-2-18(29)26-16-9-4-3-8-15(16)17-10-11-25-22-19(21(24)30)20(27-28(17)22)13-6-5-7-14(23)12-13/h2-9,12,17,25H,1,10-11H2,(H2,24,30)(H,26,29)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250037
PNG
(US10005782, Compound 159 | US9447106, 159 | US9556...)
Show SMILES COc1cc(ccc1F)-c1nn2C(CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C
Show InChI InChI=1S/C23H22FN5O3/c1-3-19(30)27-16-7-5-4-6-14(16)17-10-11-26-23-20(22(25)31)21(28-29(17)23)13-8-9-15(24)18(12-13)32-2/h3-9,12,17,26H,1,10-11H2,2H3,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250016
PNG
(US10005782, Compound 138 | US9447106, 138 | US9556...)
Show SMILES CC1(CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1)C1CCN(CC1)C(=O)C=C
Show InChI InChI=1S/C28H31N5O3/c1-3-23(34)32-17-13-20(14-18-32)28(2)15-16-30-27-24(26(29)35)25(31-33(27)28)19-9-11-22(12-10-19)36-21-7-5-4-6-8-21/h3-12,20,30H,1,13-18H2,2H3,(H2,29,35)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249900
PNG
(US10005782, Compound 27b | US9447106, 27 | US95561...)
Show SMILES NC(=O)c1c2NCCC(C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249990
PNG
(US9447106, 116 | US9556188, Compound 116)
Show SMILES NC(=O)c1c2NC[C@@H]3CN(C[C@@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C |r|
Show InChI InChI=1S/C24H23N5O3/c1-2-20(30)28-13-16-12-26-24-21(23(25)31)22(27-29(24)19(16)14-28)15-8-10-18(11-9-15)32-17-6-4-3-5-7-17/h2-11,16,19,26H,1,12-14H2,(H2,25,31)/t16-,19+/m1/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249903
PNG
(US9447106, 30 | US9556188, Compound 30)
Show SMILES NC(=O)c1c2NCC3CN(CCC3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C
Show InChI InChI=1S/C25H25N5O3/c1-2-21(31)29-13-12-20-17(15-29)14-27-25-22(24(26)32)23(28-30(20)25)16-8-10-19(11-9-16)33-18-6-4-3-5-7-18/h2-11,17,20,27H,1,12-15H2,(H2,26,32)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250071
PNG
(US10005782, Compound 196 | US9447106, 196 | US9556...)
Show SMILES NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C22H19ClFN5O2/c1-2-18(30)27-16-6-4-3-5-13(16)17-9-10-26-22-19(21(25)31)20(28-29(17)22)12-7-8-15(24)14(23)11-12/h2-8,11,17,26H,1,9-10H2,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249908
PNG
(US10005782, Compound 35 | US9447106, 35 | US955618...)
Show SMILES CN(CC1CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1)C(=O)C=C
Show InChI InChI=1S/C24H25N5O3/c1-3-20(30)28(2)15-17-13-14-26-24-21(23(25)31)22(27-29(17)24)16-9-11-19(12-10-16)32-18-7-5-4-6-8-18/h3-12,17,26H,1,13-15H2,2H3,(H2,25,31)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249966
PNG
(US10005782, Compound 92 | US9447106, 92 | US955618...)
Show SMILES CN(C)C\C=C\C(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C31H32N6O3/c1-36(2)20-8-13-27(38)34-25-12-7-6-11-24(25)26-18-19-33-31-28(30(32)39)29(35-37(26)31)21-14-16-23(17-15-21)40-22-9-4-3-5-10-22/h3-17,26,33H,18-20H2,1-2H3,(H2,32,39)(H,34,38)/b13-8+
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250050
PNG
(US10005782, Compound 172 | US9447106, 172 | US9556...)
Show SMILES COc1cc(ccc1Oc1ccccc1)-c1nn2C(CCNc2c1C(N)=O)C1CCN(CC1)C(=O)C=C
Show InChI InChI=1S/C28H31N5O4/c1-3-24(34)32-15-12-18(13-16-32)21-11-14-30-28-25(27(29)35)26(31-33(21)28)19-9-10-22(23(17-19)36-2)37-20-7-5-4-6-8-20/h3-10,17-18,21,30H,1,11-16H2,2H3,(H2,29,35)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250063
PNG
(US10005782, Compound 188 | US9447106, 188 | US9556...)
Show SMILES CN(C)CC#CC(=O)N1CCC(CC1)[C@@H]1CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C30H34N6O3/c1-34(2)18-6-9-26(37)35-19-15-21(16-20-35)25-14-17-32-30-27(29(31)38)28(33-36(25)30)22-10-12-24(13-11-22)39-23-7-4-3-5-8-23/h3-5,7-8,10-13,21,25,32H,14-20H2,1-2H3,(H2,31,38)/t25-/m0/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250061
PNG
(US10005782, Compound 186 | US9447106, 186 | US9556...)
Show SMILES CCC#CC(=O)N1CCC(CC1)[C@@H]1CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C29H31N5O3/c1-2-3-9-25(35)33-18-15-20(16-19-33)24-14-17-31-29-26(28(30)36)27(32-34(24)29)21-10-12-23(13-11-21)37-22-7-5-4-6-8-22/h4-8,10-13,20,24,31H,2,14-19H2,1H3,(H2,30,36)/t24-/m0/s1
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249977
PNG
(US10005782, Compound 103 | US9447106, 103 | US9556...)
Show SMILES NC(=O)c1c2NCCC(C3CCCN3C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C26H27N5O3/c1-2-22(32)30-16-6-9-20(30)21-14-15-28-26-23(25(27)33)24(29-31(21)26)17-10-12-19(13-11-17)34-18-7-4-3-5-8-18/h2-5,7-8,10-13,20-21,28H,1,6,9,14-16H2,(H2,27,33)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM249971
PNG
(US10005782, Compound 97 | US9447106, 97 | US955618...)
Show SMILES NC(=O)c1c2NCCC(c3ccc(Cl)c(NC(=O)C=C)c3)n2nc1-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C28H24ClN5O3/c1-2-24(35)32-22-16-18(10-13-21(22)29)23-14-15-31-28-25(27(30)36)26(33-34(23)28)17-8-11-20(12-9-17)37-19-6-4-3-5-7-19/h2-13,16,23,31H,1,14-15H2,(H2,30,36)(H,32,35)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM250030
PNG
(US10005782, Compound 152 | US9447106, 152 | US9556...)
Show SMILES NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1ccc(F)c(Br)c1
Show InChI InChI=1S/C22H19BrFN5O2/c1-2-18(30)27-16-6-4-3-5-13(16)17-9-10-26-22-19(21(25)31)20(28-29(17)22)12-7-8-15(24)14(23)11-12/h2-8,11,17,26H,1,9-10H2,(H2,25,31)(H,27,30)
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BeiGene, Ltd.

US Patent


Assay Description
Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...

US Patent US9447106 (2016)


BindingDB Entry DOI: 10.7270/Q21Z439C
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 218 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%