Affinity Data by Patent

Patent code US9447132

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM246468 (US9447132, Formula IV) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
Achillion Pharmaceuticals, Inc. US Patent					Assay Description NS5B RNA polymerase reactions for IC50 determination were performed in 96-well microtiter plates in 20 μL reactions containing assay buffer (50 ...				US Patent US9447132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X2V
Achillion Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM64587 (US9447132, GS-7977 \| sofosbuvir) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
Achillion Pharmaceuticals, Inc. US Patent					Assay Description NS5B RNA polymerase reactions for IC50 determination were performed in 96-well microtiter plates in 20 μL reactions containing assay buffer (50 ...				US Patent US9447132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X2V
Achillion Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair

* indicates data uncertainty>20%