Affinity Data by Patent

Patent code US9453017

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phospholipase D1 (Homo sapiens (Human))	BDBM247410 (US9453017, 2) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The ability of representative disclosed to block influenza infection was assessed in a cell-based assay using A549 human epithelial cells (ATCC CCL-1...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM247410 (US9453017, 2) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description In vitro PLD activity is measured with an exogenous substrate assay as previously described (Brown, H. A. et al. (1993) Cell 75:1137-1144). Briefly, ...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM247409 (US9453017, 1) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The ability of representative disclosed to block influenza infection was assessed in a cell-based assay using A549 human epithelial cells (ATCC CCL-1...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM87245 (CHEMBL492797 \| ML272 \| N-(2-(4-(2-Oxo-2,3-dihydro-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The ability of representative disclosed to block influenza infection was assessed in a cell-based assay using A549 human epithelial cells (ATCC CCL-1...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM87245 (CHEMBL492797 \| ML272 \| N-(2-(4-(2-Oxo-2,3-dihydro-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description In vitro PLD activity is measured with an exogenous substrate assay as previously described (Brown, H. A. et al. (1993) Cell 75:1137-1144). Briefly, ...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM247409 (US9453017, 1) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description In vitro PLD activity is measured with an exogenous substrate assay as previously described (Brown, H. A. et al. (1993) Cell 75:1137-1144). Briefly, ...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM87245 (CHEMBL492797 \| ML272 \| N-(2-(4-(2-Oxo-2,3-dihydro-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description In vitro PLD activity is measured with an exogenous substrate assay as previously described (Brown, H. A. et al. (1993) Cell 75:1137-1144). Briefly, ...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM87245 (CHEMBL492797 \| ML272 \| N-(2-(4-(2-Oxo-2,3-dihydro-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The ability of representative disclosed to block influenza infection was assessed in a cell-based assay using A549 human epithelial cells (ATCC CCL-1...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM247410 (US9453017, 2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description In vitro PLD activity is measured with an exogenous substrate assay as previously described (Brown, H. A. et al. (1993) Cell 75:1137-1144). Briefly, ...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM247409 (US9453017, 1) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The ability of representative disclosed to block influenza infection was assessed in a cell-based assay using A549 human epithelial cells (ATCC CCL-1...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM247410 (US9453017, 2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The ability of representative disclosed to block influenza infection was assessed in a cell-based assay using A549 human epithelial cells (ATCC CCL-1...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM247409 (US9453017, 1) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description In vitro PLD activity is measured with an exogenous substrate assay as previously described (Brown, H. A. et al. (1993) Cell 75:1137-1144). Briefly, ...				US Patent US9453017 (2016) BindingDB Entry DOI: 10.7270/Q29K495R
Vanderbilt University US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%