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Patent code US9469653

Compile Data Set for Download or QSAR
Found 23 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251807
PNG
(US9469653, 5-47)
Show SMILES Brc1ccc(cc1)-c1nc2ccc(nc2o1)N1CCCCC1
Show InChI InChI=1S/C17H16BrN3O/c18-13-6-4-12(5-7-13)16-19-14-8-9-15(20-17(14)22-16)21-10-2-1-3-11-21/h4-9H,1-3,10-11H2
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US Patent
n/an/a 96n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251804
PNG
(US9469653, 5-40)
Show SMILES Fc1cccc(c1)-c1nc2ccc(nc2o1)N1CCCCC1
Show InChI InChI=1S/C17H16FN3O/c18-13-6-4-5-12(11-13)16-19-14-7-8-15(20-17(14)22-16)21-9-2-1-3-10-21/h4-8,11H,1-3,9-10H2
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n/an/a 270n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251796
PNG
(US9469653, 5-30)
Show SMILES C1CCN(C1)c1ccc2nc(oc2n1)-c1ccccc1
Show InChI InChI=1S/C16H15N3O/c1-2-6-12(7-3-1)15-17-13-8-9-14(18-16(13)20-15)19-10-4-5-11-19/h1-3,6-9H,4-5,10-11H2
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n/an/a 410n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251808
PNG
(US9469653, 5-49)
Show SMILES COc1ccc(cc1)-c1nc2ccc(nc2o1)N1CCCCC1
Show InChI InChI=1S/C18H19N3O2/c1-22-14-7-5-13(6-8-14)17-19-15-9-10-16(20-18(15)23-17)21-11-3-2-4-12-21/h5-10H,2-4,11-12H2,1H3
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n/an/a 1.52E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251801
PNG
(US9469653, 5-37)
Show SMILES C1CCN(CC1)c1ccc2nc(oc2n1)-c1ccccc1
Show InChI InChI=1S/C17H17N3O/c1-3-7-13(8-4-1)16-18-14-9-10-15(19-17(14)21-16)20-11-5-2-6-12-20/h1,3-4,7-10H,2,5-6,11-12H2
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n/an/a 2.00E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251815
PNG
(US9469653, 5-76)
Show SMILES CNc1ccc2nc(oc2n1)-c1cccc(Cl)c1
Show InChI InChI=1S/C13H10ClN3O/c1-15-11-6-5-10-13(17-11)18-12(16-10)8-3-2-4-9(14)7-8/h2-7H,1H3,(H,15,17)
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n/an/a 2.99E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251816
PNG
(US9469653, 5-77)
Show SMILES CNc1ccc2nc(oc2n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C13H10ClN3O/c1-15-11-7-6-10-13(17-11)18-12(16-10)8-2-4-9(14)5-3-8/h2-7H,1H3,(H,15,17)
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n/an/a 3.02E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251812
PNG
(US9469653, 5-68)
Show SMILES CN(Cc1ccccc1)c1ccc2nc(oc2n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H16ClN3O/c1-24(13-14-5-3-2-4-6-14)18-12-11-17-20(23-18)25-19(22-17)15-7-9-16(21)10-8-15/h2-12H,13H2,1H3
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n/an/a 5.08E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251797
PNG
(US9469653, 5-31)
Show SMILES C1CCN(C1)c1ccc2nc(sc2n1)-c1ccccc1
Show InChI InChI=1S/C16H15N3S/c1-2-6-12(7-3-1)15-17-13-8-9-14(18-16(13)20-15)19-10-4-5-11-19/h1-3,6-9H,4-5,10-11H2
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n/an/a 7.30E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251802
PNG
(US9469653, 5-38)
Show SMILES C1CCN(CC1)c1ccc2nc(sc2n1)-c1ccccc1
Show InChI InChI=1S/C17H17N3S/c1-3-7-13(8-4-1)16-18-14-9-10-15(19-17(14)21-16)20-11-5-2-6-12-20/h1,3-4,7-10H,2,5-6,11-12H2
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n/an/a 8.30E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251800
PNG
(US9469653, 5-34)
Show SMILES Fc1ccc(cc1)-c1nc2ccc(nc2o1)N1CCCC1
Show InChI InChI=1S/C16H14FN3O/c17-12-5-3-11(4-6-12)15-18-13-7-8-14(19-16(13)21-15)20-9-1-2-10-20/h3-8H,1-2,9-10H2
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n/an/a 8.70E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251817
PNG
(US9469653, 5-80)
Show SMILES C1CCC(CC1)Nc1ccc2nc(oc2n1)-c1ccccc1
Show InChI InChI=1S/C18H19N3O/c1-3-7-13(8-4-1)17-20-15-11-12-16(21-18(15)22-17)19-14-9-5-2-6-10-14/h1,3-4,7-8,11-12,14H,2,5-6,9-10H2,(H,19,21)
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n/an/a 8.72E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r|
Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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US Patent
n/an/a 9.70E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251814
PNG
(US9469653, 5-75)
Show SMILES CNc1ccc2nc(oc2n1)-c1cccc(F)c1
Show InChI InChI=1S/C13H10FN3O/c1-15-11-6-5-10-13(17-11)18-12(16-10)8-3-2-4-9(14)7-8/h2-7H,1H3,(H,15,17)
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n/an/a 9.86E+3n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251806
PNG
(US9469653, 5-45)
Show SMILES Fc1ccc(cc1)-c1nc2ccc(nc2o1)N1CCCCC1
Show InChI InChI=1S/C17H16FN3O/c18-13-6-4-12(5-7-13)16-19-14-8-9-15(20-17(14)22-16)21-10-2-1-3-11-21/h4-9H,1-3,10-11H2
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n/an/a 1.01E+4n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251803
PNG
(US9469653, 5-39)
Show SMILES Clc1ccccc1-c1nc2ccc(nc2o1)N1CCCCC1
Show InChI InChI=1S/C17H16ClN3O/c18-13-7-3-2-6-12(13)16-19-14-8-9-15(20-17(14)22-16)21-10-4-1-5-11-21/h2-3,6-9H,1,4-5,10-11H2
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n/an/a 1.32E+4n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251813
PNG
(US9469653, 5-74)
Show SMILES CNc1ccc2nc(sc2n1)-c1ccccc1
Show InChI InChI=1S/C13H11N3S/c1-14-11-8-7-10-13(16-11)17-12(15-10)9-5-3-2-4-6-9/h2-8H,1H3,(H,14,16)
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n/an/a 1.57E+4n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251799
PNG
(US9469653, 5-33)
Show SMILES Clc1cccc(c1)-c1nc2ccc(nc2o1)N1CCCC1
Show InChI InChI=1S/C16H14ClN3O/c17-12-5-3-4-11(10-12)15-18-13-6-7-14(19-16(13)21-15)20-8-1-2-9-20/h3-7,10H,1-2,8-9H2
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n/an/a 1.63E+4n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251805
PNG
(US9469653, 5-41)
Show SMILES Clc1cccc(c1)-c1nc2ccc(nc2o1)N1CCCCC1
Show InChI InChI=1S/C17H16ClN3O/c18-13-6-4-5-12(11-13)16-19-14-7-8-15(20-17(14)22-16)21-9-2-1-3-10-21/h4-8,11H,1-3,9-10H2
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n/an/a 3.84E+4n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251811
PNG
(US9469653, 5-67)
Show SMILES CN(Cc1ccccc1)c1ccc2nc(oc2n1)-c1cccc(Cl)c1
Show InChI InChI=1S/C20H16ClN3O/c1-24(13-14-6-3-2-4-7-14)18-11-10-17-20(23-18)25-19(22-17)15-8-5-9-16(21)12-15/h2-12H,13H2,1H3
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n/an/a 6.82E+4n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251798
PNG
(US9469653, 5-32)
Show SMILES Clc1ccccc1-c1nc2ccc(nc2o1)N1CCCC1
Show InChI InChI=1S/C16H14ClN3O/c17-12-6-2-1-5-11(12)15-18-13-7-8-14(19-16(13)21-15)20-9-3-4-10-20/h1-2,5-8H,3-4,9-10H2
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n/an/a 1.12E+5n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251809
PNG
(US9469653, 5-58)
Show SMILES C(Nc1ccc2nc(sc2n1)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C19H15N3S/c1-3-7-14(8-4-1)13-20-17-12-11-16-19(22-17)23-18(21-16)15-9-5-2-6-10-15/h1-12H,13H2,(H,20,22)
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n/an/a 1.90E+6n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM251810
PNG
(US9469653, 5-63)
Show SMILES CN(Cc1ccccc1)c1ccc2nc(oc2n1)-c1ccccc1
Show InChI InChI=1S/C20H17N3O/c1-23(14-15-8-4-2-5-9-15)18-13-12-17-20(22-18)24-19(21-17)16-10-6-3-7-11-16/h2-13H,14H2,1H3
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n/an/a 5.20E+7n/an/an/an/an/an/a



KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent


Assay Description
A stock solution was prepared using a human MAO-B enzyme (purchased from Aldrich) and a Amplex Red monoamine oxidase assay kit according to a prepara...


US Patent US9469653 (2016)


BindingDB Entry DOI: 10.7270/Q2V9870D
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%