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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251901 (US9475809, 13 | US9918969, 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 34 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251900 (US9475809, 12 | US9918969, 12) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251904 (US9475809, 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 77 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251903 (US9475809, 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 98 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251895 (BDBM376543 | US9475809, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 130 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251902 (US9475809, 14 | US9918969, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251897 (US9475809, 9 | US9918969, 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 170 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251898 (US9475809, 10 | US9918969, 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 190 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251891 (US9475809, 3 | US9918969, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 230 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251893 (US9475809, 5 | US9918969, 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 330 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251890 (US9475809, 2 | US9918969, 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251892 (US9475809, 4 | US9918969, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 420 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251896 (US9475809, 8 | US9918969, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 470 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251894 (US9475809, 6 | US9918969, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251899 (US9475809, 11 | US9918969, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 750 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM251889 (US9475809, 1 | US9918969, 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 930 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ... | US Patent US9475809 (2016) BindingDB Entry DOI: 10.7270/Q2G15ZRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
