BindingDB logo
myBDB logout

Patent code US9487462

Compile Data Set for Download or QSAR
Found 114 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

US Patent
n/an/a 0.100n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

US Patent
n/an/a 0.200n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

US Patent
n/an/a 0.5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

US Patent
n/an/a 1n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256139
PNG
(US9487462, 22)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OC(c3ccccc3)c3ccccc3)cc2)n1
Show InChI InChI=1S/C32H28FN3O3/c33-27-15-11-23(12-16-27)20-36(22-30-34-19-29(35-30)32(37)38)21-24-13-17-28(18-14-24)39-31(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-19,31H,20-22H2,(H,34,35)(H,37,38)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 280n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256127
PNG
(US9487462, 9)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-5-1-18(2-6-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-3-7-22(8-4-19)32-16-20-9-11-27-12-10-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.24E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256131
PNG
(US9487462, 13)
Show SMILES OC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-20-10-12-26-13-11-20)14-19-6-8-22(9-7-19)31-17-21-4-2-1-3-5-21/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256128
PNG
(US9487462, 10)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-19-3-1-9-25-11-19)13-18-5-7-21(8-6-18)31-16-20-4-2-10-26-12-20/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256125
PNG
(US9487462, 6)
Show SMILES OC(=O)c1csc(CN(CC(c2ccccc2)c2ccccc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C33H30N2O3S/c36-33(37)31-24-39-32(34-31)22-35(21-30(27-12-6-2-7-13-27)28-14-8-3-9-15-28)20-25-16-18-29(19-17-25)38-23-26-10-4-1-5-11-26/h1-19,24,30H,20-23H2,(H,36,37)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.76E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.76E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256120
PNG
(US9487462, 1)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-7-3-18(4-8-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-5-9-22(10-6-19)32-16-20-2-1-11-27-12-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256133
PNG
(US9487462, 15)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C25H21FN2O2S/c26-22-12-8-19(9-13-22)15-28(16-24-27-23(17-31-24)25(29)30)14-18-6-10-21(11-7-18)20-4-2-1-3-5-20/h1-13,17H,14-16H2,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256126
PNG
(US9487462, 7)
Show SMILES OC(=O)c1csc(CN(Cc2ccccc2)Cc2ccccc2)n1
Show InChI InChI=1S/C19H18N2O2S/c22-19(23)17-14-24-18(20-17)13-21(11-15-7-3-1-4-8-15)12-16-9-5-2-6-10-16/h1-10,14H,11-13H2,(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.20E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.30E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256121
PNG
(US9487462, 2)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-5-9-23(28)10-6-20)16-21-7-11-24(12-8-21)34-18-22-4-3-13-29-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.70E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.90E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256124
PNG
(US9487462, 5)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccc(F)c2)n1
Show InChI InChI=1S/C26H23FN2O3S/c27-22-8-4-7-21(13-22)15-29(16-25-28-24(18-33-25)26(30)31)14-19-9-11-23(12-10-19)32-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.70E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256134
PNG
(US9487462, 16)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-23-9-6-14-28-15-23)16-21-10-12-24(13-11-21)33-19-22-7-4-3-5-8-22/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256120
PNG
(US9487462, 1)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-7-3-18(4-8-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-5-9-22(10-6-19)32-16-20-2-1-11-27-12-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.70E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256124
PNG
(US9487462, 5)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccc(F)c2)n1
Show InChI InChI=1S/C26H23FN2O3S/c27-22-8-4-7-21(13-22)15-29(16-25-28-24(18-33-25)26(30)31)14-19-9-11-23(12-10-19)32-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 6.60E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256138
PNG
(US9487462, 20)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-22-12-14-28-15-13-22)16-21-8-10-24(11-9-21)33-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256127
PNG
(US9487462, 9)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-5-1-18(2-6-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-3-7-22(8-4-19)32-16-20-9-11-27-12-10-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256139
PNG
(US9487462, 22)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OC(c3ccccc3)c3ccccc3)cc2)n1
Show InChI InChI=1S/C32H28FN3O3/c33-27-15-11-23(12-16-27)20-36(22-30-34-19-29(35-30)32(37)38)21-24-13-17-28(18-14-24)39-31(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-19,31H,20-22H2,(H,34,35)(H,37,38)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256132
PNG
(US9487462, 14)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-21-7-4-12-26-13-21)14-19-8-10-22(11-9-19)31-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256130
PNG
(US9487462, 12)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-20-2-1-9-26-12-20)13-18-3-5-21(6-4-18)31-16-19-7-10-25-11-8-19/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256127
PNG
(US9487462, 9)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-5-1-18(2-6-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-3-7-22(8-4-19)32-16-20-9-11-27-12-10-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.80E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256124
PNG
(US9487462, 5)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccc(F)c2)n1
Show InChI InChI=1S/C26H23FN2O3S/c27-22-8-4-7-21(13-22)15-29(16-25-28-24(18-33-25)26(30)31)14-19-9-11-23(12-10-19)32-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.80E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256126
PNG
(US9487462, 7)
Show SMILES OC(=O)c1csc(CN(Cc2ccccc2)Cc2ccccc2)n1
Show InChI InChI=1S/C19H18N2O2S/c22-19(23)17-14-24-18(20-17)13-21(11-15-7-3-1-4-8-15)12-16-9-5-2-6-10-16/h1-10,14H,11-13H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256125
PNG
(US9487462, 6)
Show SMILES OC(=O)c1csc(CN(CC(c2ccccc2)c2ccccc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C33H30N2O3S/c36-33(37)31-24-39-32(34-31)22-35(21-30(27-12-6-2-7-13-27)28-14-8-3-9-15-28)20-25-16-18-29(19-17-25)38-23-26-10-4-1-5-11-26/h1-19,24,30H,20-23H2,(H,36,37)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256142
PNG
(US9487462, 31)
Show SMILES OC(=O)c1c[nH]c(CNCc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C18H18N4O3/c23-18(24)16-10-21-17(22-16)11-20-8-13-3-5-15(6-4-13)25-12-14-2-1-7-19-9-14/h1-7,9-10,20H,8,11-12H2,(H,21,22)(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256126
PNG
(US9487462, 7)
Show SMILES OC(=O)c1csc(CN(Cc2ccccc2)Cc2ccccc2)n1
Show InChI InChI=1S/C19H18N2O2S/c22-19(23)17-14-24-18(20-17)13-21(11-15-7-3-1-4-8-15)12-16-9-5-2-6-10-16/h1-10,14H,11-13H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256136
PNG
(US9487462, 18)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-3-7-23(28)8-4-20)16-21-5-9-24(10-6-21)34-18-22-11-13-29-14-12-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.30E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256126
PNG
(US9487462, 7)
Show SMILES OC(=O)c1csc(CN(Cc2ccccc2)Cc2ccccc2)n1
Show InChI InChI=1S/C19H18N2O2S/c22-19(23)17-14-24-18(20-17)13-21(11-15-7-3-1-4-8-15)12-16-9-5-2-6-10-16/h1-10,14H,11-13H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.30E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.30E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.50E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256139
PNG
(US9487462, 22)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OC(c3ccccc3)c3ccccc3)cc2)n1
Show InChI InChI=1S/C32H28FN3O3/c33-27-15-11-23(12-16-27)20-36(22-30-34-19-29(35-30)32(37)38)21-24-13-17-28(18-14-24)39-31(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-19,31H,20-22H2,(H,34,35)(H,37,38)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.60E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256133
PNG
(US9487462, 15)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C25H21FN2O2S/c26-22-12-8-19(9-13-22)15-28(16-24-27-23(17-31-24)25(29)30)14-18-6-10-21(11-7-18)20-4-2-1-3-5-20/h1-13,17H,14-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256137
PNG
(US9487462, 19)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-22-4-3-11-28-14-22)15-20-5-7-23(8-6-20)33-18-21-9-12-27-13-10-21/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256135
PNG
(US9487462, 17)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-21-5-3-11-27-13-21)15-20-7-9-23(10-8-20)33-18-22-6-4-12-28-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256133
PNG
(US9487462, 15)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C25H21FN2O2S/c26-22-12-8-19(9-13-22)15-28(16-24-27-23(17-31-24)25(29)30)14-18-6-10-21(11-7-18)20-4-2-1-3-5-20/h1-13,17H,14-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256124
PNG
(US9487462, 5)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccc(F)c2)n1
Show InChI InChI=1S/C26H23FN2O3S/c27-22-8-4-7-21(13-22)15-29(16-25-28-24(18-33-25)26(30)31)14-19-9-11-23(12-10-19)32-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.50E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256125
PNG
(US9487462, 6)
Show SMILES OC(=O)c1csc(CN(CC(c2ccccc2)c2ccccc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C33H30N2O3S/c36-33(37)31-24-39-32(34-31)22-35(21-30(27-12-6-2-7-13-27)28-14-8-3-9-15-28)20-25-16-18-29(19-17-25)38-23-26-10-4-1-5-11-26/h1-19,24,30H,20-23H2,(H,36,37)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.60E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256125
PNG
(US9487462, 6)
Show SMILES OC(=O)c1csc(CN(CC(c2ccccc2)c2ccccc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C33H30N2O3S/c36-33(37)31-24-39-32(34-31)22-35(21-30(27-12-6-2-7-13-27)28-14-8-3-9-15-28)20-25-16-18-29(19-17-25)38-23-26-10-4-1-5-11-26/h1-19,24,30H,20-23H2,(H,36,37)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.60E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256129
PNG
(US9487462, 11)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C28H27FN2O3S/c1-2-33-28(32)26-20-35-27(30-26)18-31(16-21-8-12-24(29)13-9-21)17-22-10-14-25(15-11-22)34-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.70E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256133
PNG
(US9487462, 15)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C25H21FN2O2S/c26-22-12-8-19(9-13-22)15-28(16-24-27-23(17-31-24)25(29)30)14-18-6-10-21(11-7-18)20-4-2-1-3-5-20/h1-13,17H,14-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256143
PNG
(US9487462, 32)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C27H25FN2O2S/c1-2-32-27(31)25-19-33-26(29-25)18-30(17-21-10-14-24(28)15-11-21)16-20-8-12-23(13-9-20)22-6-4-3-5-7-22/h3-15,19H,2,16-18H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.10E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.30E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256140
PNG
(US9487462, 26)
Show SMILES Cn1cc(nc1CN(Cc1ccc(F)cc1)Cc1ccc(OCc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C27H25F4N3O/c1-33-17-25(27(29,30)31)32-26(33)18-34(15-20-7-11-23(28)12-8-20)16-21-9-13-24(14-10-21)35-19-22-5-3-2-4-6-22/h2-14,17H,15-16,18-19H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.40E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256139
PNG
(US9487462, 22)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OC(c3ccccc3)c3ccccc3)cc2)n1
Show InChI InChI=1S/C32H28FN3O3/c33-27-15-11-23(12-16-27)20-36(22-30-34-19-29(35-30)32(37)38)21-24-13-17-28(18-14-24)39-31(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-19,31H,20-22H2,(H,34,35)(H,37,38)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.50E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256120
PNG
(US9487462, 1)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-7-3-18(4-8-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-5-9-22(10-6-19)32-16-20-2-1-11-27-12-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.70E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256127
PNG
(US9487462, 9)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-5-1-18(2-6-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-3-7-22(8-4-19)32-16-20-9-11-27-12-10-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.70E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256120
PNG
(US9487462, 1)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-7-3-18(4-8-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-5-9-22(10-6-19)32-16-20-2-1-11-27-12-20/h1-12,17H,13-16H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.10E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256131
PNG
(US9487462, 13)
Show SMILES OC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-20-10-12-26-13-11-20)14-19-6-8-22(9-7-19)31-17-21-4-2-1-3-5-21/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.40E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256147
PNG
(US9487462, 38)
Show SMILES O=C(N1CCCC1)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C16H19N3O/c20-16(19-10-4-5-11-19)14-12-17-15(18-14)9-8-13-6-2-1-3-7-13/h1-3,6-7,12H,4-5,8-11H2,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.40E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256147
PNG
(US9487462, 38)
Show SMILES O=C(N1CCCC1)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C16H19N3O/c20-16(19-10-4-5-11-19)14-12-17-15(18-14)9-8-13-6-2-1-3-7-13/h1-3,6-7,12H,4-5,8-11H2,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.20E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256146
PNG
(US9487462, 37)
Show SMILES COC(=O)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C13H14N2O2/c1-17-13(16)11-9-14-12(15-11)8-7-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 6.60E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256147
PNG
(US9487462, 38)
Show SMILES O=C(N1CCCC1)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C16H19N3O/c20-16(19-10-4-5-11-19)14-12-17-15(18-14)9-8-13-6-2-1-3-7-13/h1-3,6-7,12H,4-5,8-11H2,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256132
PNG
(US9487462, 14)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-21-7-4-12-26-13-21)14-19-8-10-22(11-9-19)31-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256143
PNG
(US9487462, 32)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C27H25FN2O2S/c1-2-32-27(31)25-19-33-26(29-25)18-30(17-21-10-14-24(28)15-11-21)16-20-8-12-23(13-9-20)22-6-4-3-5-7-22/h3-15,19H,2,16-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.00E+4n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256121
PNG
(US9487462, 2)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-5-9-23(28)10-6-20)16-21-7-11-24(12-8-21)34-18-22-4-3-13-29-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.05E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256131
PNG
(US9487462, 13)
Show SMILES OC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-20-10-12-26-13-11-20)14-19-6-8-22(9-7-19)31-17-21-4-2-1-3-5-21/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.15E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50329857
PNG
(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Show SMILES OC(=O)c1cnc([nH]1)-c1ccccc1
Show InChI InChI=1S/C10H8N2O2/c13-10(14)8-6-11-9(12-8)7-4-2-1-3-5-7/h1-6H,(H,11,12)(H,13,14)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
MMDB
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 1.37E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256129
PNG
(US9487462, 11)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C28H27FN2O3S/c1-2-33-28(32)26-20-35-27(30-26)18-31(16-21-8-12-24(29)13-9-21)17-22-10-14-25(15-11-22)34-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256146
PNG
(US9487462, 37)
Show SMILES COC(=O)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C13H14N2O2/c1-17-13(16)11-9-14-12(15-11)8-7-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.45E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256121
PNG
(US9487462, 2)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-5-9-23(28)10-6-20)16-21-7-11-24(12-8-21)34-18-22-4-3-13-29-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.63E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50329857
PNG
(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Show SMILES OC(=O)c1cnc([nH]1)-c1ccccc1
Show InChI InChI=1S/C10H8N2O2/c13-10(14)8-6-11-9(12-8)7-4-2-1-3-5-7/h1-6H,(H,11,12)(H,13,14)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
MMDB
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 1.65E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256121
PNG
(US9487462, 2)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-5-9-23(28)10-6-20)16-21-7-11-24(12-8-21)34-18-22-4-3-13-29-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.85E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256137
PNG
(US9487462, 19)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-22-4-3-11-28-14-22)15-20-5-7-23(8-6-20)33-18-21-9-12-27-13-10-21/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256135
PNG
(US9487462, 17)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-21-5-3-11-27-13-21)15-20-7-9-23(10-8-20)33-18-22-6-4-12-28-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.95E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256137
PNG
(US9487462, 19)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-22-4-3-11-28-14-22)15-20-5-7-23(8-6-20)33-18-21-9-12-27-13-10-21/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256135
PNG
(US9487462, 17)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-21-5-3-11-27-13-21)15-20-7-9-23(10-8-20)33-18-22-6-4-12-28-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256143
PNG
(US9487462, 32)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C27H25FN2O2S/c1-2-32-27(31)25-19-33-26(29-25)18-30(17-21-10-14-24(28)15-11-21)16-20-8-12-23(13-9-20)22-6-4-3-5-7-22/h3-15,19H,2,16-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256136
PNG
(US9487462, 18)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-3-7-23(28)8-4-20)16-21-5-9-24(10-6-21)34-18-22-11-13-29-14-12-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.30E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256135
PNG
(US9487462, 17)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-21-5-3-11-27-13-21)15-20-7-9-23(10-8-20)33-18-22-6-4-12-28-14-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.30E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256142
PNG
(US9487462, 31)
Show SMILES OC(=O)c1c[nH]c(CNCc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C18H18N4O3/c23-18(24)16-10-21-17(22-16)11-20-8-13-3-5-15(6-4-13)25-12-14-2-1-7-19-9-14/h1-7,9-10,20H,8,11-12H2,(H,21,22)(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.35E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256132
PNG
(US9487462, 14)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-21-7-4-12-26-13-21)14-19-8-10-22(11-9-19)31-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM50329857
PNG
(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Show SMILES OC(=O)c1cnc([nH]1)-c1ccccc1
Show InChI InChI=1S/C10H8N2O2/c13-10(14)8-6-11-9(12-8)7-4-2-1-3-5-7/h1-6H,(H,11,12)(H,13,14)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
MMDB
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 2.50E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256134
PNG
(US9487462, 16)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-23-9-6-14-28-15-23)16-21-10-12-24(13-11-21)33-19-22-7-4-3-5-8-22/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.80E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256129
PNG
(US9487462, 11)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C28H27FN2O3S/c1-2-33-28(32)26-20-35-27(30-26)18-31(16-21-8-12-24(29)13-9-21)17-22-10-14-25(15-11-22)34-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.80E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256145
PNG
(US9487462, 36)
Show SMILES OC(=O)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C12H12N2O2/c15-12(16)10-8-13-11(14-10)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,13,14)(H,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256138
PNG
(US9487462, 20)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-22-12-14-28-15-13-22)16-21-8-10-24(11-9-21)33-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.25E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256134
PNG
(US9487462, 16)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-23-9-6-14-28-15-23)16-21-10-12-24(13-11-21)33-19-22-7-4-3-5-8-22/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.40E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256148
PNG
(US9487462, 39)
Show SMILES FC(F)(F)c1cnc([nH]1)-c1ccccc1
Show InChI InChI=1S/C10H7F3N2/c11-10(12,13)8-6-14-9(15-8)7-4-2-1-3-5-7/h1-6H,(H,14,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 3.40E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256138
PNG
(US9487462, 20)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-22-12-14-28-15-13-22)16-21-8-10-24(11-9-21)33-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256130
PNG
(US9487462, 12)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-20-2-1-9-26-12-20)13-18-3-5-21(6-4-18)31-16-19-7-10-25-11-8-19/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256140
PNG
(US9487462, 26)
Show SMILES Cn1cc(nc1CN(Cc1ccc(F)cc1)Cc1ccc(OCc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C27H25F4N3O/c1-33-17-25(27(29,30)31)32-26(33)18-34(15-20-7-11-23(28)12-8-20)16-21-9-13-24(14-10-21)35-19-22-5-3-2-4-6-22/h2-14,17H,15-16,18-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256142
PNG
(US9487462, 31)
Show SMILES OC(=O)c1c[nH]c(CNCc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C18H18N4O3/c23-18(24)16-10-21-17(22-16)11-20-8-13-3-5-15(6-4-13)25-12-14-2-1-7-19-9-14/h1-7,9-10,20H,8,11-12H2,(H,21,22)(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256137
PNG
(US9487462, 19)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C26H26N4O3S/c1-2-32-26(31)24-19-34-25(29-24)17-30(16-22-4-3-11-28-14-22)15-20-5-7-23(8-6-20)33-18-21-9-12-27-13-10-21/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256140
PNG
(US9487462, 26)
Show SMILES Cn1cc(nc1CN(Cc1ccc(F)cc1)Cc1ccc(OCc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C27H25F4N3O/c1-33-17-25(27(29,30)31)32-26(33)18-34(15-20-7-11-23(28)12-8-20)16-21-9-13-24(14-10-21)35-19-22-5-3-2-4-6-22/h2-14,17H,15-16,18-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256148
PNG
(US9487462, 39)
Show SMILES FC(F)(F)c1cnc([nH]1)-c1ccccc1
Show InChI InChI=1S/C10H7F3N2/c11-10(12,13)8-6-14-9(15-8)7-4-2-1-3-5-7/h1-6H,(H,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256129
PNG
(US9487462, 11)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C28H27FN2O3S/c1-2-33-28(32)26-20-35-27(30-26)18-31(16-21-8-12-24(29)13-9-21)17-22-10-14-25(15-11-22)34-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256143
PNG
(US9487462, 32)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C27H25FN2O2S/c1-2-32-27(31)25-19-33-26(29-25)18-30(17-21-10-14-24(28)15-11-21)16-20-8-12-23(13-9-20)22-6-4-3-5-7-22/h3-15,19H,2,16-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256146
PNG
(US9487462, 37)
Show SMILES COC(=O)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C13H14N2O2/c1-17-13(16)11-9-14-12(15-11)8-7-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,14,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256136
PNG
(US9487462, 18)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-3-7-23(28)8-4-20)16-21-5-9-24(10-6-21)34-18-22-11-13-29-14-12-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256138
PNG
(US9487462, 20)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-22-12-14-28-15-13-22)16-21-8-10-24(11-9-21)33-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256144
PNG
(US9487462, 35)
Show SMILES FC(F)(F)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C12H11F3N2/c13-12(14,15)10-8-16-11(17-10)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256144
PNG
(US9487462, 35)
Show SMILES FC(F)(F)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C12H11F3N2/c13-12(14,15)10-8-16-11(17-10)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256132
PNG
(US9487462, 14)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-21-7-4-12-26-13-21)14-19-8-10-22(11-9-19)31-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256142
PNG
(US9487462, 31)
Show SMILES OC(=O)c1c[nH]c(CNCc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C18H18N4O3/c23-18(24)16-10-21-17(22-16)11-20-8-13-3-5-15(6-4-13)25-12-14-2-1-7-19-9-14/h1-7,9-10,20H,8,11-12H2,(H,21,22)(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256128
PNG
(US9487462, 10)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-19-3-1-9-25-11-19)13-18-5-7-21(8-6-18)31-16-20-4-2-10-26-12-20/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256140
PNG
(US9487462, 26)
Show SMILES Cn1cc(nc1CN(Cc1ccc(F)cc1)Cc1ccc(OCc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C27H25F4N3O/c1-33-17-25(27(29,30)31)32-26(33)18-34(15-20-7-11-23(28)12-8-20)16-21-9-13-24(14-10-21)35-19-22-5-3-2-4-6-22/h2-14,17H,15-16,18-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256130
PNG
(US9487462, 12)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-20-2-1-9-26-12-20)13-18-3-5-21(6-4-18)31-16-19-7-10-25-11-8-19/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256134
PNG
(US9487462, 16)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-23-9-6-14-28-15-23)16-21-10-12-24(13-11-21)33-19-22-7-4-3-5-8-22/h3-15,20H,2,16-19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256130
PNG
(US9487462, 12)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-20-2-1-9-26-12-20)13-18-3-5-21(6-4-18)31-16-19-7-10-25-11-8-19/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256136
PNG
(US9487462, 18)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-3-7-23(28)8-4-20)16-21-5-9-24(10-6-21)34-18-22-11-13-29-14-12-22/h3-14,19H,2,15-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256128
PNG
(US9487462, 10)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-19-3-1-9-25-11-19)13-18-5-7-21(8-6-18)31-16-20-4-2-10-26-12-20/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256145
PNG
(US9487462, 36)
Show SMILES OC(=O)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C12H12N2O2/c15-12(16)10-8-13-11(14-10)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,13,14)(H,15,16)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256144
PNG
(US9487462, 35)
Show SMILES FC(F)(F)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C12H11F3N2/c13-12(14,15)10-8-16-11(17-10)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256131
PNG
(US9487462, 13)
Show SMILES OC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-20-10-12-26-13-11-20)14-19-6-8-22(9-7-19)31-17-21-4-2-1-3-5-21/h1-13,18H,14-17H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256128
PNG
(US9487462, 10)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-19-3-1-9-25-11-19)13-18-5-7-21(8-6-18)31-16-20-4-2-10-26-12-20/h1-12,17H,13-16H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256148
PNG
(US9487462, 39)
Show SMILES FC(F)(F)c1cnc([nH]1)-c1ccccc1
Show InChI InChI=1S/C10H7F3N2/c11-10(12,13)8-6-14-9(15-8)7-4-2-1-3-5-7/h1-6H,(H,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256145
PNG
(US9487462, 36)
Show SMILES OC(=O)c1cnc(CCc2ccccc2)[nH]1
Show InChI InChI=1S/C12H12N2O2/c15-12(16)10-8-13-11(14-10)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,13,14)(H,15,16)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%