Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 [42-168] (Homo sapiens (Human)) | BDBM254914 (US9493483, 402) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Constellation Pharmaceuticals, Inc. US Patent | Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ... | US Patent US9493483 (2016) BindingDB Entry DOI: 10.7270/Q26D5RXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [42-168] (Homo sapiens (Human)) | BDBM50158612 (CHEMBL3787075 | US9493483, 401) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Constellation Pharmaceuticals, Inc. US Patent | Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ... | US Patent US9493483 (2016) BindingDB Entry DOI: 10.7270/Q26D5RXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [42-168] (Homo sapiens (Human)) | BDBM50158612 (CHEMBL3787075 | US9493483, 401) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Constellation Pharmaceuticals, Inc. US Patent | Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ... | US Patent US9493483 (2016) BindingDB Entry DOI: 10.7270/Q26D5RXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [42-168] (Homo sapiens (Human)) | BDBM254915 (US9493483, 403) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Constellation Pharmaceuticals, Inc. US Patent | Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ... | US Patent US9493483 (2016) BindingDB Entry DOI: 10.7270/Q26D5RXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [42-168] (Homo sapiens (Human)) | BDBM254917 (US9493483, 405) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 175 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Constellation Pharmaceuticals, Inc. US Patent | Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ... | US Patent US9493483 (2016) BindingDB Entry DOI: 10.7270/Q26D5RXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [42-168] (Homo sapiens (Human)) | BDBM254916 (US9493483, 404) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 270 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Constellation Pharmaceuticals, Inc. US Patent | Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ... | US Patent US9493483 (2016) BindingDB Entry DOI: 10.7270/Q26D5RXQ | |||||||||||
More data for this Ligand-Target Pair |