Affinity Data by Patent

Patent code US9512082

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM258436 (US9512082, 1) Show SMILES COc1ccc(NC(=O)NCCCn2cncc2C)cc1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	31.2	-43.6	192	n/a	n/a	n/a	n/a	8.0	30
PROBIODRUG AG US Patent					Assay Description For inhibitor testing, the sample composition was the same as described below, except of the putative inhibitory compound added. For a rapid test of ...				US Patent US9512082 (2016) BindingDB Entry DOI: 10.7270/Q2CR5S92
PROBIODRUG AG US Patent					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM258437 (US9512082, 2) Show SMILES COc1ccc(NC(=O)NCCCn2cncc2C)cc1OC1CCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	60	-41.9	343	n/a	n/a	n/a	n/a	8.0	30
PROBIODRUG AG US Patent					Assay Description For inhibitor testing, the sample composition was the same as described below, except of the putative inhibitory compound added. For a rapid test of ...				US Patent US9512082 (2016) BindingDB Entry DOI: 10.7270/Q2CR5S92
PROBIODRUG AG US Patent					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM258442 (US9512082, 7) Show SMILES COc1ccc(CNC(=O)Nc2ccc3[nH]cnc3c2)cc1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	171	-39.3	1.67E+3	n/a	n/a	n/a	n/a	8.0	30
PROBIODRUG AG US Patent					Assay Description For inhibitor testing, the sample composition was the same as described below, except of the putative inhibitory compound added. For a rapid test of ...				US Patent US9512082 (2016) BindingDB Entry DOI: 10.7270/Q2CR5S92
PROBIODRUG AG US Patent					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM258441 (US9512082, 6) Show SMILES COc1ccc(NC(=O)NCc2ccc3nc[nH]c3c2)cc1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	458	-36.8	4.25E+3	n/a	n/a	n/a	n/a	8.0	30
PROBIODRUG AG US Patent					Assay Description For inhibitor testing, the sample composition was the same as described below, except of the putative inhibitory compound added. For a rapid test of ...				US Patent US9512082 (2016) BindingDB Entry DOI: 10.7270/Q2CR5S92
PROBIODRUG AG US Patent					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM258438 (US9512082, 3) Show SMILES COc1ccc(NC(=O)NCCCn2cnc(C)c2)cc1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.77E+3	-33.4	1.40E+4	n/a	n/a	n/a	n/a	8.0	30
PROBIODRUG AG US Patent					Assay Description For inhibitor testing, the sample composition was the same as described below, except of the putative inhibitory compound added. For a rapid test of ...				US Patent US9512082 (2016) BindingDB Entry DOI: 10.7270/Q2CR5S92
PROBIODRUG AG US Patent					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM258440 (US9512082, 5) Show SMILES COc1ccc(NC(=O)Nc2ccc3[nH]cnc3c2)cc1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.98E+3	-32.1	2.62E+4	n/a	n/a	n/a	n/a	8.0	30
PROBIODRUG AG US Patent					Assay Description For inhibitor testing, the sample composition was the same as described below, except of the putative inhibitory compound added. For a rapid test of ...				US Patent US9512082 (2016) BindingDB Entry DOI: 10.7270/Q2CR5S92
PROBIODRUG AG US Patent					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM258439 (US9512082, 4) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.82E+3	n/a	n/a	n/a	n/a	8.0	30
PROBIODRUG AG US Patent					Assay Description For inhibitor testing, the sample composition was the same as described below, except of the putative inhibitory compound added. For a rapid test of ...				US Patent US9512082 (2016) BindingDB Entry DOI: 10.7270/Q2CR5S92
PROBIODRUG AG US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%