Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen (88/88 = 100%)† (Homo sapiens (Human)) | BDBM50357211 (177 J.D. | AMINOCAPROIC ACID | Amicar | Aminocapro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | DrugBank PDB Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Binding affinity to full length Glu-plasminogen in human plasma assessed as inhibition of interaction with fibrin in presence of tPA | ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Plasminogen (88/88 = 100%)† (Homo sapiens (Human)) | BDBM50357211 (177 J.D. | AMINOCAPROIC ACID | Amicar | Aminocapro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | DrugBank PDB Article PubMed | n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Binding affinity to human full length Glu-plasminogen in buffer assessed as inhibition of interaction with fibrin preincubated for 15 mins followed b... | ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |