Affinity Data by PDB ID

PDB code 1GI6

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine protease 1 (223/223 = 100%)^† (Bos taurus (bovine))	BDBM13942 (2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE \| A...) Show SMILES NC(=[NH2+])c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	1.70E+3	-32.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Axys Pharmaceuticals Corporation					Assay Description Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...				J Mol Biol 307: 1451-86 (2001) Article DOI: 10.1006/jmbi.2001.4516 BindingDB Entry DOI: 10.7270/Q2FX77PG
Axys Pharmaceuticals Corporation					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output