Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase (247/247 = 100%)† (Methanosarcina thermophila) | BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL | Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay | Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase (247/247 = 100%)† (Methanosarcina thermophila) | BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Bioscienze e Biorisorse Curated by ChEMBL | Assay Description Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assay | Bioorg Med Chem 23: 4405-9 (2015) Article DOI: 10.1016/j.bmc.2015.06.021 BindingDB Entry DOI: 10.7270/Q2JD4ZJ0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase (247/247 = 100%)† (Methanosarcina thermophila) | BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Italy; Universit£ degliStudi di Firenze Curated by ChEMBL | Assay Description Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin... | Bioorg Med Chem 25: 575-580 (2017) Article DOI: 10.1016/j.bmc.2016.11.021 BindingDB Entry DOI: 10.7270/Q2M047FF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase (247/247 = 100%)† (Methanosarcina thermophila) | BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory constant against Zn-Cam (Methanosarcina thermophila) | Bioorg Med Chem Lett 14: 4563-7 (2004) Article DOI: 10.1016/j.bmcl.2004.06.073 BindingDB Entry DOI: 10.7270/Q2H995ZD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase (247/247 = 100%)† (Methanosarcina thermophila) | BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory constant against Zn-Cam (Methanosarcina thermophila) | Bioorg Med Chem Lett 14: 4563-7 (2004) Article DOI: 10.1016/j.bmcl.2004.06.073 BindingDB Entry DOI: 10.7270/Q2H995ZD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |