Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor VII (57/57 = 100%)† (Homo sapiens (Human)) | BDBM13552 ((2S)-2-[(2R)-2-[4-(benzyloxy)-3-methoxyphenyl]-2-[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | 4 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
F. Hoffmann-La Roche Ltd. | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | Bioorg Med Chem Lett 15: 817-22 (2005) Article DOI: 10.1016/j.bmcl.2004.10.092 BindingDB Entry DOI: 10.7270/Q2SF2TFR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor VII (57/57 = 100%)† (Homo sapiens (Human)) | BDBM13552 ((2S)-2-[(2R)-2-[4-(benzyloxy)-3-methoxyphenyl]-2-[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | 4 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
F. Hoffmann-La Roche Ltd. | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | Bioorg Med Chem Lett 15: 5344-52 (2005) Article DOI: 10.1016/j.bmcl.2005.04.079 BindingDB Entry DOI: 10.7270/Q2X63K6X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |