Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chitotriosidase-1 (445/445 = 100%)† (Homo sapiens (Human)) | BDBM10853 ((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | 5.5 | n/a |
University of Dundee | Assay Description Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT. | Chem Biol 15: 295-301 (2008) Article DOI: 10.1016/j.chembiol.2008.02.015 BindingDB Entry DOI: 10.7270/Q2JH3JN1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Chitotriosidase-1 (445/445 = 100%)† (Homo sapiens (Human)) | BDBM10853 ((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | 5.2 | 37 |
University of Dundee | Assay Description The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa... | Chem Biol 12: 65-76 (2005) Article DOI: 10.1016/j.chembiol.2004.10.013 BindingDB Entry DOI: 10.7270/Q23F4MV6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |