Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-dependent protein kinase catalytic subunit alpha (346/350 = 99%)† (Bos taurus (bovine)) | BDBM11818 ((3R,4R)-N-(4-{4-[3-(3,3-dimethylpiperidin-2-yl)-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | 7.2 | 22 |
Max-Planck-Institut fuer Biochemie | Assay Description In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a... | J Med Chem 48: 163-70 (2005) Article DOI: 10.1021/jm049701n BindingDB Entry DOI: 10.7270/Q21C1V3S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |