Affinity Data by PDB ID

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PDB code 1ZNC

Identical Ligands in BindingDB

Found 5 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 4 (266/266 = 100%)^† (Homo sapiens (Human))	BDBM26992 (CHEMBL183495 \| SO4(2-) \| SODIUM SULFATE \| sulfate ...) Show SMILES [O-]S([O-])(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	9.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				Bioorg Med Chem Lett 19: 1155-8 (2009) Article DOI: 10.1016/j.bmcl.2008.12.082 BindingDB Entry DOI: 10.7270/Q2KD1W79
Universita degli Studi di Firenze					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 4 (266/266 = 100%)^† (Homo sapiens (Human))	BDBM26992 (CHEMBL183495 \| SO4(2-) \| SODIUM SULFATE \| sulfate ...) Show SMILES [O-]S([O-])(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	9.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against human Carbonic anhydrase IV				Bioorg Med Chem Lett 15: 567-71 (2005) Article DOI: 10.1016/j.bmcl.2004.11.056 BindingDB Entry DOI: 10.7270/Q22R3SDV
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 4 (266/266 = 100%)^† (Homo sapiens (Human))	BDBM26992 (CHEMBL183495 \| SO4(2-) \| SODIUM SULFATE \| sulfate ...) Show SMILES [O-]S([O-])(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	9.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ondokuz Mayis University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curves				Bioorg Med Chem 19: 744-8 (2011) Article DOI: 10.1016/j.bmc.2010.12.033 BindingDB Entry DOI: 10.7270/Q2ST7QT4
Ondokuz Mayis University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 4 (266/266 = 100%)^† (Homo sapiens (Human))	BDBM26992 (CHEMBL183495 \| SO4(2-) \| SODIUM SULFATE \| sulfate ...) Show SMILES [O-]S([O-])(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	9.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 4 (266/266 = 100%)^† (Homo sapiens (Human))	BDBM26992 (CHEMBL183495 \| SO4(2-) \| SODIUM SULFATE \| sulfate ...) Show SMILES [O-]S([O-])(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.40E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory constant against carbonic anhydrase IV				Bioorg Med Chem Lett 14: 4563-7 (2004) Article DOI: 10.1016/j.bmcl.2004.06.073 BindingDB Entry DOI: 10.7270/Q2H995ZD
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

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_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output