Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase   (158/159 > 99%)† (Escherichia coli)	BDBM18052 (3-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)me...) Show SMILES NC(=N)NC(=N)SCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C10H11F3N4S/c11-10(12,13)7-3-1-2-6(4-7)5-18-9(16)17-8(14)15/h1-4H,5H2,(H5,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	7.0	30
University of Prince Edward Island					Assay Description The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...				J Med Chem 49: 6977-86 (2006) Article DOI: 10.1021/jm060570v BindingDB Entry DOI: 10.7270/Q2T43RCM
					More data for this Ligand-Target Pair				3D Structure (crystal)

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