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PDB code 2EVM

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 4 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase

  (264/264 = 100%)
(Escherichia coli (strain K12))
BDBM50175451
PNG
(5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...)
Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)
PDB
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MCE
MMDB
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PC sid
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PDB
Article
PubMed
n/an/a 693n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Mn(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase

  (264/264 = 100%)
(Escherichia coli (strain K12))
BDBM50175451
PNG
(5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...)
Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

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PDB
Article
PubMed
n/an/a 8.40E+4n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Fe(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase

  (264/264 = 100%)
(Escherichia coli (strain K12))
BDBM50175451
PNG
(5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...)
Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

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MMDB
PDB
Article
PubMed
n/an/a 1.26E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Co(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase

  (264/264 = 100%)
(Escherichia coli (strain K12))
BDBM50175451
PNG
(5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...)
Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Similars

DrugBank
MMDB
PDB
Article
PubMed
n/an/a 1.73E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Ni(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output