Affinity Data by PDB ID

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PDB code 2IEH

Identical Ligands in BindingDB

Found 4 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kinesin-like protein KIF11 (367/367 = 100%)^† (Homo sapiens (Human))	BDBM50260279 ((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Commissariat à l'Energie Atomique-Université Joseph Fourier Curated by ChEMBL					Assay Description Inhibition of basal ATPase activity of human Eg5				J Biol Chem 282: 9740-7 (2007) Article DOI: 10.1074/jbc.M608883200 BindingDB Entry DOI: 10.7270/Q2K64HVW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (367/367 = 100%)^† (Homo sapiens (Human))	BDBM50260279 ((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of Eg5 basal ATPase activity (unknown origin)				Eur J Med Chem 62: 614-31 (2013) Article DOI: 10.1016/j.ejmech.2013.01.031 BindingDB Entry DOI: 10.7270/Q2KH0PP9
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (367/367 = 100%)^† (Homo sapiens (Human))	BDBM50260279 ((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)				Eur J Med Chem 62: 614-31 (2013) Article DOI: 10.1016/j.ejmech.2013.01.031 BindingDB Entry DOI: 10.7270/Q2KH0PP9
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (367/367 = 100%)^† (Homo sapiens (Human))	BDBM50260279 ((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Commissariat à l'Energie Atomique-Université Joseph Fourier Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated human Eg5 ATPase activity				J Biol Chem 282: 9740-7 (2007) Article DOI: 10.1074/jbc.M608883200 BindingDB Entry DOI: 10.7270/Q2K64HVW
					More data for this Ligand-Target Pair				3D Structure (crystal)

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_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output