Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-dependent protein kinase catalytic subunit alpha (347/351 = 99%)† (Bos taurus (bovine)) | BDBM16222 (CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | 7.2 | 22 |
Astex | Assay Description The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P... | J Med Chem 50: 2289-92 (2007) Article DOI: 10.1021/jm0700924 BindingDB Entry DOI: 10.7270/Q2M32T1C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (347/351 = 99%)† (Bos taurus (bovine)) | BDBM16222 (CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | 7.2 | 22 |
Astex | Assay Description The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P... | J Mol Biol 367: 882-94 (2007) Article DOI: 10.1016/j.jmb.2007.01.004 BindingDB Entry DOI: 10.7270/Q29Z934H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (347/351 = 99%)† (Bos taurus (bovine)) | BDBM16222 (CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | 7.2 | 22 |
UK Centre for Cancer Therapeutics | Assay Description The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P... | Bioorg Med Chem 14: 1255-73 (2006) Article DOI: 10.1016/j.bmc.2005.09.055 BindingDB Entry DOI: 10.7270/Q2FN14F2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |