Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orotidine-5'-phosphate decarboxylase (323/323 = 100%)† (Plasmodium falciparum (malaria parasite P. falcipa...) | BDBM21338 (6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.10E+3 | -33.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Toronto General Research Institute | Assay Description An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p... | J Med Chem 51: 439-48 (2008) Article DOI: 10.1021/jm7010673 BindingDB Entry DOI: 10.7270/Q27H1GWS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |