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PDB code 2Q94

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 4 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase

  (262/262 = 100%)
(Escherichia coli (strain K12))
BDBM50175458
PNG
(5-(2-(trifluoromethoxy)phenyl)furan-2-carboxylic a...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1OC(F)(F)F
Show InChI InChI=1S/C12H7F3O4/c13-12(14,15)19-9-4-2-1-3-7(9)8-5-6-10(18-8)11(16)17/h1-6H,(H,16,17)
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n/an/a 368n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Mn(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase

  (262/262 = 100%)
(Escherichia coli (strain K12))
BDBM50175458
PNG
(5-(2-(trifluoromethoxy)phenyl)furan-2-carboxylic a...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1OC(F)(F)F
Show InChI InChI=1S/C12H7F3O4/c13-12(14,15)19-9-4-2-1-3-7(9)8-5-6-10(18-8)11(16)17/h1-6H,(H,16,17)
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Article
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n/an/a 1.70E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Co(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase

  (262/262 = 100%)
(Escherichia coli (strain K12))
BDBM50175458
PNG
(5-(2-(trifluoromethoxy)phenyl)furan-2-carboxylic a...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1OC(F)(F)F
Show InChI InChI=1S/C12H7F3O4/c13-12(14,15)19-9-4-2-1-3-7(9)8-5-6-10(18-8)11(16)17/h1-6H,(H,16,17)
PDB
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KEGG

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Article
PubMed
n/an/a 1.91E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Fe(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase

  (262/262 = 100%)
(Escherichia coli (strain K12))
BDBM50175458
PNG
(5-(2-(trifluoromethoxy)phenyl)furan-2-carboxylic a...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1OC(F)(F)F
Show InChI InChI=1S/C12H7F3O4/c13-12(14,15)19-9-4-2-1-3-7(9)8-5-6-10(18-8)11(16)17/h1-6H,(H,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

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PDB
Article
PubMed
n/an/a 1.97E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Ni(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output