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PDB code 2R9S

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10

  (356/356 = 100%)
(Homo sapiens (Human))
BDBM50224009
PNG
(CHEMBL250409 | N-(tert-butyl)-4-[5-(pyridin-2-ylam...)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(cc1)-c1cnc2cccc(Nc3ccccn3)c2c1
Show InChI InChI=1S/C24H24N4O2S/c1-24(2,3)28-31(29,30)19-12-10-17(11-13-19)18-15-20-21(26-16-18)7-6-8-22(20)27-23-9-4-5-14-25-23/h4-16,28H,1-3H3,(H,25,27)
PDB
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NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
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Similars

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Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Scripps Florida

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by HTRF assay


Bioorg Med Chem Lett 17: 6378-82 (2007)


Article DOI: 10.1016/j.bmcl.2007.08.054
BindingDB Entry DOI: 10.7270/Q26M36KX
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output