Identical Ligands in BindingDB

Found 2 hits Enzyme Inhibition Constant Data   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2   (322/322 = 100%)† (Homo sapiens (Human))	BDBM50309182 (4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...) Show SMILES NC(=O)c1ccc(cc1)-c1cc(cnc1N)-c1scc2OCCOc12 Show InChI InChI=1S/C18H15N3O3S/c19-17-13(10-1-3-11(4-2-10)18(20)22)7-12(8-21-17)16-15-14(9-25-16)23-5-6-24-15/h1-4,7-9H,5-6H2,(H2,19,21)(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk2   (322/322 = 100%)† (Homo sapiens (Human))	BDBM50309182 (4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...) Show SMILES NC(=O)c1ccc(cc1)-c1cc(cnc1N)-c1scc2OCCOc12 Show InChI InChI=1S/C18H15N3O3S/c19-17-13(10-1-3-11(4-2-10)18(20)22)7-12(8-21-17)16-15-14(9-25-16)23-5-6-24-15/h1-4,7-9H,5-6H2,(H2,19,21)(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western bloting				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair				3D Structure (crystal)

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