Found 4 hits Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Calcium/calmodulin-dependent protein kinase kinase 2
(291/291 = 100%)† (Homo sapiens (Human)) | BDBM92455
(CHEMBL265470 | STO-609)Show InChI InChI=1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee
Curated by ChEMBL
| Assay Description Inhibition of CAMKKbeta in the presence of 20uM ATP |
Biochem J 408: 297-315 (2007)
Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Calcium/calmodulin-dependent protein kinase kinase 2
(291/291 = 100%)† (Homo sapiens (Human)) | BDBM92455
(CHEMBL265470 | STO-609)Show InChI InChI=1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of CaM-KKbeta |
Proc Natl Acad Sci USA 104: 20523-8 (2007)
Checked by Author Article DOI: 10.1073/pnas.0708800104 BindingDB Entry DOI: 10.7270/Q2DB82RH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Calcium/calmodulin-dependent protein kinase kinase 2
(291/291 = 100%)† (Homo sapiens (Human)) | BDBM92455
(CHEMBL265470 | STO-609)Show InChI InChI=1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | 7.5 | 30 |
RIKEN Systems and Structural Biology Center
| Assay Description The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio... |
J Biol Chem 286: 22570-9 (2011)
Article DOI: 10.1074/jbc.M111.251710 BindingDB Entry DOI: 10.7270/Q2445K3H |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Calcium/calmodulin-dependent protein kinase kinase 2 [ P274E]
(290/291 > 99%)† (Homo sapiens (Human)) | BDBM92455
(CHEMBL265470 | STO-609)Show InChI InChI=1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 2.42E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
RIKEN Systems and Structural Biology Center
| Assay Description The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio... |
J Biol Chem 286: 22570-9 (2011)
Article DOI: 10.1074/jbc.M111.251710 BindingDB Entry DOI: 10.7270/Q2445K3H |
More data for this Ligand-Target Pair | 3D Structure (crystal) |