Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptide deformylase, mitochondrial (180/180 = 100%)† (Homo sapiens (Human)) | BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity of the compound towards Peptide deformylase | Bioorg Med Chem Lett 13: 3273-6 (2003) BindingDB Entry DOI: 10.7270/Q2FN15MQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptide deformylase, mitochondrial (180/180 = 100%)† (Homo sapiens (Human)) | BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description In vitro inhibitory concentration required against peptide deformylase (PDF) | Bioorg Med Chem Lett 13: 3273-6 (2003) BindingDB Entry DOI: 10.7270/Q2FN15MQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptide deformylase, mitochondrial (180/180 = 100%)† (Homo sapiens (Human)) | BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
British Biotech Pharmaceuticals Limited Curated by ChEMBL | Assay Description Antibacterial activity of the compound against E. coli Peptide deformylase. Ni | Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptide deformylase, mitochondrial (180/180 = 100%)† (Homo sapiens (Human)) | BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique Curated by ChEMBL | Assay Description Inhibition of human mitochondrial PDF | J Med Chem 50: 10-20 (2007) Article DOI: 10.1021/jm060910c BindingDB Entry DOI: 10.7270/Q22Z16B7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptide deformylase, mitochondrial (180/180 = 100%)† (Homo sapiens (Human)) | BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Inhibition of human peptide deformylase after 1 hr by fluorescence polarization based competition assay | Bioorg Med Chem Lett 21: 4528-32 (2011) Article DOI: 10.1016/j.bmcl.2011.05.129 BindingDB Entry DOI: 10.7270/Q2VT1SGT | |||||||||||
More data for this Ligand-Target Pair |