BindingDB logo
myBDB logout

PDB code 3I7I

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Collagenase 3

  (171/171 = 100%)
(Homo sapiens (Human))
BDBM32396
PNG
(furan-2-carboxamide deriv., 2)
Show SMILES CNC(=O)[C@@H](NC(=O)c1ccc(o1)-c1ccc(NC(=O)c2cc3ccccc3o2)cc1)C1CCCCC1 |r|
Show InChI InChI=1S/C29H29N3O5/c1-30-29(35)26(19-7-3-2-4-8-19)32-27(33)24-16-15-23(36-24)18-11-13-21(14-12-18)31-28(34)25-17-20-9-5-6-10-22(20)37-25/h5-6,9-17,19,26H,2-4,7-8H2,1H3,(H,30,35)(H,31,34)(H,32,33)/t26-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

MMDB
PDB
Article
PubMed
n/an/a 620n/an/an/an/a7.537



Boehringer Ingelheim Pharmaceuticals



Assay Description
MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...


Bioorg Med Chem Lett 19: 5321-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.151
BindingDB Entry DOI: 10.7270/Q22B8WCD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output