Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (395/395 = 100%)† (Homo sapiens (Human)) | BDBM50300239 (3-(3-(((furan-2-ylmethyl)(methyl)amino)methyl)phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of BACE1 by HTRF assay | J Med Chem 53: 942-50 (2010) Article DOI: 10.1021/jm901472u BindingDB Entry DOI: 10.7270/Q2348KDC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |