Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (367/367 = 100%)† (Homo sapiens (Human)) | BDBM50313600 (2-(3-(3,5-dichlorophenyl)ureido)benzoic acid | 2-{...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-aventis Curated by ChEMBL | Assay Description Inhibition of recombinant human DHODH by using blue indicator dye DCIP | Bioorg Med Chem Lett 20: 1981-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.115 BindingDB Entry DOI: 10.7270/Q2CF9Q7R | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |