Identical Ligands in BindingDB

Found 2 hits Enzyme Inhibition Constant Data   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1   (321/322 > 99%)† (Homo sapiens (Human))	BDBM50321564 (5-acetyl-2-(2-fluoro-4-iodophenylamino)-N-(2-hydro...) Show SMILES CC(=O)c1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)n1C Show InChI InChI=1S/C16H17FIN3O4/c1-9(23)14-8-11(16(24)20-25-6-5-22)15(21(14)2)19-13-4-3-10(18)7-12(13)17/h3-4,7-8,19,22H,5-6H2,1-2H3,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Curated by ChEMBL					Assay Description Inhibition of MEK1-mediated ERK1 phosphorylation using IPTTPITTYFFFK-5FAM-COOH as substrate by fluorescent polarization assay				Bioorg Med Chem Lett 22: 2411-4 (2012) Article DOI: 10.1016/j.bmcl.2012.02.026 BindingDB Entry DOI: 10.7270/Q2BR8T5H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dual specificity mitogen-activated protein kinase kinase 1   (321/322 > 99%)† (Homo sapiens (Human))	BDBM50321564 (5-acetyl-2-(2-fluoro-4-iodophenylamino)-N-(2-hydro...) Show SMILES CC(=O)c1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)n1C Show InChI InChI=1S/C16H17FIN3O4/c1-9(23)14-8-11(16(24)20-25-6-5-22)15(21(14)2)19-13-4-3-10(18)7-12(13)17/h3-4,7-8,19,22H,5-6H2,1-2H3,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego Curated by ChEMBL					Assay Description Inhibition of MEK1 by cascade assay method				Bioorg Med Chem Lett 20: 4156-8 (2010) Article DOI: 10.1016/j.bmcl.2010.05.058 BindingDB Entry DOI: 10.7270/Q2SF2X4Z
					More data for this Ligand-Target Pair				3D Structure (crystal)

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