Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-1 (285/285 = 100%)† (Homo sapiens (Human)) | BDBM50345259 (CHEMBL1782530 | cis-7-(4-aminocyclohexylamino)-5-b...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Zarqa University Curated by ChEMBL | Assay Description Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysis | Bioorg Med Chem 25: 4855-4875 (2017) Article DOI: 10.1016/j.bmc.2017.07.036 BindingDB Entry DOI: 10.7270/Q2BC420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (285/285 = 100%)† (Homo sapiens (Human)) | BDBM50345259 (CHEMBL1782530 | cis-7-(4-aminocyclohexylamino)-5-b...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corp. Curated by ChEMBL | Assay Description Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift method | Bioorg Med Chem Lett 21: 3050-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.030 BindingDB Entry DOI: 10.7270/Q2ZP46GG | |||||||||||
More data for this Ligand-Target Pair |