Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 2 (298/298 = 100%)† (Homo sapiens (Human)) | BDBM92562 (Hit compound, 3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Moffitt Cancer Center and Research Institute | Assay Description The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA) | Chembiochem 13: 2128-36 (2012) Article DOI: 10.1002/cbic.201200316 BindingDB Entry DOI: 10.7270/Q2154FN2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |