Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 (126/127 > 99%)† (Homo sapiens (Human)) | BDBM50001728 (8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 2.46E+3 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Binding affinity to BRD4-BD1 by isothermal titration calorimetry | Bioorg Med Chem 20: 1878-86 (2012) Article DOI: 10.1016/j.bmc.2011.10.080 BindingDB Entry DOI: 10.7270/Q2NC61PZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |