Affinity Data by PDB ID

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PDB code 3VOB

Identical Ligands in BindingDB

Found 4 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cell division protein FtsZ (306/307 > 99%)^† (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein FtsZ (306/307 > 99%)^† (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Prolysis Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Science 321: 1673-5 (2008) Article DOI: 10.1126/science.1159961 BindingDB Entry DOI: 10.7270/Q2HX1GG1
Prolysis Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein FtsZ (306/307 > 99%)^† (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0
Stony Brook University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein FtsZ (306/307 > 99%)^† (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Activation of Staphylococcus aureus FtsZ GTPase activity				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
University of California at Davis Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

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_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output