Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (544/545 > 99%)† (Mus musculus (mouse)) | BDBM50443030 (CHEMBL3087808) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University Curated by ChEMBL | Assay Description Inhibition of mouse recombinant AChE using acetylthiocholine iodide as substrate by Ellman's method | J Med Chem 56: 7615-24 (2013) Article DOI: 10.1021/jm400990p BindingDB Entry DOI: 10.7270/Q24M95Z3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Acetylcholinesterase (544/545 > 99%)† (Mus musculus (mouse)) | BDBM50443030 (CHEMBL3087808) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a | n/a |
Ume£ University Curated by ChEMBL | Assay Description Binding affinity to mouse AChE by isothermal titration calorimetry | J Med Chem 56: 7615-24 (2013) Article DOI: 10.1021/jm400990p BindingDB Entry DOI: 10.7270/Q24M95Z3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |